Search results for "Diffuse"
showing 10 items of 276 documents
Factors related to the relative survival of patients with diffuse large B-cell lymphoma in a population-based study in France: does socio-economic st…
2017
IF 7.702; International audience; The survival of patients with diffuse large B-cell lymphoma has increased during the last decade as a result of addition of anti-CD20 to anthracycline-based chemotherapy. Although the trend is encouraging, there are persistent differences in survival within and between the USA and European countries suggesting that non-biological factors play a role. Our aim was to investigate the influence of such factors on relative survival of patients with diffuse large B-cell lymphoma. We conducted a retrospective, multicenter, registry-based study in France on 1165 incident cases of diffuse large B-cell lymphoma between 2002 and 2008. Relative survival analyses were p…
Search for low-energy neutrinos from astrophysical sources with Borexino
2019
We report on searches for neutrinos and antineutrinos from astrophysical sources performed with the Borexino detector at the Laboratori Nazionali del Gran Sasso in Italy. Electron antineutrinos ($\bar{\nu}_e$) are detected in an organic liquid scintillator through the inverse $\beta$-decay reaction. In the present work we set model-independent upper limits in the energy range 1.8-16.8 MeV on neutrino fluxes from unknown sources that improve our previous results, on average, by a factor 2.5. Using the same data set, we first obtain experimental constraints on the diffuse supernova $\bar{\nu}_e$ fluxes in the previously unexplored region below 8 MeV. A search for $\bar{\nu}_e$ in the solar ne…
Spectral calibration of hyperspectral imagery using atmospheric absorption features
2006
One of the initial steps in the preprocessing of remote sensing data is the atmospheric correction of the at-sensor radiance images, i.e., radiances recorded at the sensor aperture. Apart from the accuracy in the estimation of the concentrations of the main atmospheric species, the retrieved surface reflectance is also influenced by the spectral calibration of the sensor, especially in those wavelengths mostly affected by gaseous absorptions. In particular, errors in the surface reflectance appear when a systematic shift in the nominal channel positions occurs. A method to assess the spectral calibration of hyperspectral imaging spectrometers from the acquired imagery is presented in this p…
Phantoms Used for Mapping of Skin Chromophores by Multi-spectral Imaging
2014
Skin phantoms can be used for better understanding of diffuse reflectance imaging of skin. In this study, skin phantoms of hemoglobin, bilirubin and melanin were developed and studied for possibilities to calibrate chromophore concentration values.
Measurement of haemodynamics of exercising and non-exercising vastus lateralis muscle with hybrid diffuse optics
2016
We present simultaneous diffuse correlation spectroscopy (DCS) and time resolved spectroscopy (TR NIRS) measurements on exercising and non-exercising vastus lateralis muscle. We discuss the results at two different exercise levels.
Glofitamab (Glofit) in Combination with Polatuzumab Vedotin (Pola): Phase Ib/II Preliminary Data Support Manageable Safety and Encouraging Efficacy i…
2021
Abstract Background: Glofit is a novel, CD20xCD3 T-cell-engaging bispecific antibody that provides monovalent binding to CD3 on T cells and bivalent binding to CD20 on B cells. As monotherapy, Glofit has shown promising response rates with manageable safety in R/R B-cell non-Hodgkin lymphoma (B-NHL) patients (pts; [Carlo-Stella et al. EHA 2021]). Because of their distinct and complementary mechanism of action, there is a rationale for combining Glofit with the anti-CD79b-targeted antibody-drug conjugate, Pola. NP39488 (NCT03533283) is a Phase Ib/II, open-label, multicenter, dose-escalation (DE) and expansion study evaluating Glofit + Pola or atezolizumab in R/R B-NHL pts (Hutchings et al. A…
Ultraviolet radiation protection by a beach umbrella.
2010
A beach umbrella intercepts all direct UV irradiance, but only part of the diffuse component. Using a simple sky view factor model, we have determined the fraction of the hemispheric diffuse irradiance that is not intercepted by the umbrella. Assuming a sensor at the surface and close to the center of the umbrella, isotropic diffuse irradiance and for an umbrella of 80 cm radius and 100 cm high, our results show that approximately 34% of the incident horizontal irradiance is not intercepted by the umbrella. These results agree with irradiance measurements conducted with and without the umbrella. The model is next extended to examine receipt of UV radiation by a human figure in a vertical po…
Non-porous polybutadiene-coated silicas as stationary phases in reversed-phase chromatography
1990
Abstract Non-porous silica of mean particle diameter 1.7 μm (Monospher) was coated with polybutadiene (PBD) following a published procedure. The silicas were prepared with graduated polymer loads up to 8% (w/w). Examination of the PBD-coated packings by means of electron spectroscopy for chemical analysis, scanning electron microscopy, diffuse reflection infrared fourier transform spectroscopy and differential thermal gravimetry indicated that the optimum polymer load was between 1 and 3% (w/w) with regard to a dense coverage corresponding to an average layer thickness of about 4 nm. No silanophilic interactions could be monitored using 1–3% (w/w) coated silicas under reversed-phase conditi…
ChemInform Abstract: In situ DRIFT Spectroscopic Investigation on the Chemical Evolution of Zinc Phosphate Acid-Base Cement.
2010
Diffuse reflectance infrared Fourier transform (DRIFT) spectroscopy has been used to follow the chemical evolution of zinc phosphate acid−base cement (ZPC), which has been prepared from unmodified, as well as from aluminum- and zinc-modified orthophosphoric acid. For the first time, amorphous dizinc cyclotetraphosphate octahydrate, Zn2P4O12·8H2O, although hydrolytically instable, has been observed as precursor phase prior to crystallization of α-hopeite, α-Zn3(PO4)2·4H2O, in both systems. Within minutes from onset of mixing the infrared spectrum of unmodified ZPC is dominated by the characteristic vibrations of α-hopeite, due to matrix crystallization. Setting of modified ZPC is strongly af…
Increased conformational rigidity of humic substances by oxidative biomimetic catalysis
2005
A synthetic water-soluble meso-tetra(2,6-dichloro-3-sulfonatophenyl)porphyrinate of iron(III) chloride, Fe(TDCPPS)Cl, was employed as a biomimetic catalyst in the oxidative coupling of terrestrial humic materials. High-performance size-exclusion chromatography (HPSEC), solid-state nuclear magnetic resonance (CPMAS-(13)C NMR), electron paramagnetic resonance (EPR), and diffuse reflectance infrared spectroscopy (DRIFT) were used to follow conformational and structural changes brought about in different humic materials by the oxidative coupling. Increase in apparent weight-average molecular weight (Mw(a)) occurred invariably for all humic substances with the oxidative polymerization catalyzed …