Search results for "Diol"

showing 10 items of 11756 documents

Co-activation and tension-regulating phenomena during isokinetic knee extension in sedentary and highly skilled humans.

1996

The aim of this study was to examine isokinetic torque produced by highly skilled (HS) and sedentary (S) human subjects, during knee extension, during maximal voluntary and superimposed electrical activation. To verify the level of activation of agonist (vastus lateralis, VL, and vastus medialis, VM) and antagonist muscles (semi-tendineous, ST), during maximal voluntary activation, their myo-electrical activities were detected and quantified as root mean square (rms) amplitude. Ten HS and ten S subjects performed voluntary and superimposed isometric actions and isokinetic knee extensions at 14 angular velocities (from -120 to 300 degrees*s(-1)). The rms amplitude of each muscle was normaliz…

AdultMaleVolitionmedicine.medical_specialtygenetic structuresPhysiologyVastus medialisIsometric exerciseConcentricRoot mean squarePhysiology (medical)Internal medicinemedicineTorqueEccentricHumansOrthopedics and Sports MedicineKneeMuscle SkeletalPhysicsPhysical Education and TrainingPublic Health Environmental and Occupational HealthGeneral MedicineAnatomyElectric StimulationElectrophysiologyAmplitudeTorqueCardiologymedicine.symptomMuscle contractionMuscle ContractionEuropean journal of applied physiology and occupational physiology
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Increased plasma xanthine oxidase activity is related to nuclear factor kappa beta activation and inflammatory markers in familial combined hyperlipi…

2010

Abstract Background and aims Xanthine oxidase (XO) has been described as one of the major enzymes producing free radicals in blood. Oxidative stress and inflammatory processes have been implicated in the pathogenesis of endothelial dysfunction and the progression of atherosclerosis but until now, there is little data about the influence of vascular prooxidant systems and inflammation in familial combined hyperlipidemia (FCH). Our goal was to evaluate whether XO activity was altered in FCH and if it was related to the inflammatory process represented by NFkB, IL-6 and hsCRP, and assessing the correlation between XO activity and insulin resistance (IR). Method and results 40 Non-related subje…

AdultMaleXanthine Oxidasemedicine.medical_specialtyFree RadicalsEndocrinology Diabetes and Metabolismmedicine.medical_treatmentHyperlipidemia Familial CombinedMedicine (miscellaneous)Inflammationmedicine.disease_causechemistry.chemical_compoundInsulin resistanceMalondialdehydeInternal medicineHyperlipidemiamedicineHumansXanthine oxidaseInflammationNutrition and Dieteticsmedicine.diagnostic_testInterleukin-6business.industryInsulinNF-kappa BMiddle AgedAtherosclerosismedicine.diseaseLipidsOxidative StressC-Reactive ProteinLogistic ModelsEndocrinologychemistryMultivariate AnalysisUric acidFemaleEndothelium VascularLipid PeroxidationInsulin Resistancemedicine.symptomCardiology and Cardiovascular MedicineLipid profilebusinessBiomarkersOxidative stressNutrition, Metabolism and Cardiovascular Diseases
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Posterior interosseous nerve of the elbow at the arcade of Frohse: Ultrasound appearance in asymptomatic subjects

2019

PURPOSE To assess the normal values of the antero-posterior (AP) diameter of the posterior interosseous nerve (PIN) of the elbow as it passes beneath the arcade of Frohse and to search for PIN-diameter differences between the upstream, entry point and downstream of the arcade. MATERIAL AND METHODS Thirty asymptomatic patients prospectively underwent bilateral B-mode ultrasound of the PIN of the elbow. There were 15 men and 15 women with a mean age of 30.2±5.31 (SD) years (range: 26-43 years). Of these, 23 patients were right-handers (23/30; 77%) and 7 were left handers (7/30; 23%). AP diameter of the PIN was measured in long axis at three different locations including the entry point of the…

AdultMale[SDV]Life Sciences [q-bio]ElbowNormal valuesAsymptomatic030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineElbowmedicineHumansSupinator muscleRadiology Nuclear Medicine and imagingProspective StudiesUltrasonographyLeft handedRadiological and Ultrasound Technologybusiness.industryNerve Compression SyndromesUltrasoundPeripheral Nervous System DiseasesMean ageGeneral MedicineAnatomyPosterior interosseous nervemedicine.anatomical_structure030220 oncology & carcinogenesisAsymptomatic DiseasesFemaleRadial Nervemedicine.symptombusiness
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Patterned functional network disruption in amyotrophic lateral sclerosis

2019

Abstract Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease primarily affecting motor function, with additional evidence of extensive nonmotor involvement. Despite increasing recognition of the disease as a multisystem network disorder characterised by impaired connectivity, the precise neuroelectric characteristics of impaired cortical communication remain to be fully elucidated. Here, we characterise changes in functional connectivity using beamformer source analysis on resting‐state electroencephalography recordings from 74 ALS patients and 47 age‐matched healthy controls. Spatiospectral characteristics of network changes in the ALS patient group were quantifi…

AdultMaleamyotrophic lateral sclerosisNeuropsychological TestsElectroencephalographyBiology050105 experimental psychologyFunctional networksCorrelationmotor neurone disease03 medical and health sciencesCognition0302 clinical medicinemedicineHumanssource localisation0501 psychology and cognitive sciencesRadiology Nuclear Medicine and imagingEEGTheta RhythmAmyotrophic lateral sclerosisresting stateResearch ArticlesAgedCerebral CortexBrain MappingRadiological and Ultrasound TechnologyResting state fMRImedicine.diagnostic_testFunctional connectivityfunctional connectivity05 social sciencesElectroencephalographyCognitionMiddle Agedmedicine.diseaseMagnetic Resonance ImagingDelta RhythmNeurologyFemaleNeurology (clinical)Nerve NetAnatomyBeta RhythmNeuroscienceMotor neurone diseasePsychomotor Performance030217 neurology & neurosurgeryResearch ArticleHuman Brain Mapping
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Diffusion-tensor MR imaging at 1.5 and 3.0 T: initial observations.

2001

Diffusion-tensor MR imaging was compared at 1.5 and 3.0 T. With sufficient signal-to-noise ratio, we found no differences in fractional anisotropy. With a 40% higher signal-to-noise ratio at 3.0 T, higher resolution could be obtained without introduction of noise-related errors, albeit at the cost of increased geometric distortions caused by 3.0-T magnetic field inhomogeneities.

AdultMalebusiness.industryPhantoms ImagingResolution (electron density)BrainMagnetic Resonance ImagingMagnetic fieldNuclear magnetic resonanceSignal-to-noise ratio (imaging)Fractional anisotropySpin echoMedicineHumansRadiology Nuclear Medicine and imagingFemaleTensorDiffusion (business)businessDiffusion MRIRadiology
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Nitric oxide metabolites (nitrite and nitrate) in young patients with recent acute myocardial infarction

2008

Nitric oxide (NO) has a role in the pathophysiology of acute and chronic cardiovascular events. We studied the plasma concentration of NO stable end products (nitrite and nitrate - NO x ) in 43 patients aged <46 years, with recent acute myocardial infarction (AMI). The evaluation was effected at the initial stage, after 3 and 12 months. We subdivided the patients into subgroups according to the number of the main cardiovascular risk factors and to the extent of coronary disease. In the whole group the NO x concentration was initially increased and progressively decreased after 3 and 12 months, remaining at both times significantly higher than in control subjects. The patients with more risk…

AdultMalecardiovascular risk factorsmedicine.medical_specialtyPhysiologyCardiovascular risk factorsMyocardial Infarctionacute myocardial infarctionNitric oxidechemistry.chemical_compoundNitrateRisk FactorsnitratePhysiology (medical)Internal medicinemedicineHumansMyocardial infarctionNitritenitriteNitritesInflammationNitratesbusiness.industryNitric oxideHematologymedicine.diseaseControl subjectsPathophysiologychemistryPlasma concentrationCardiologyFemaleCardiology and Cardiovascular MedicinebusinessClinical Hemorheology and Microcirculation
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Relationship between albumin excretion rate and aortic stiffness in untreated essential hypertensive patients

2004

. Objectives.  To evaluate, in a group of nondiabetic essential hypertensive patients with normal renal function, the relationship between albumin excretion rate (AER) and carotid-femoral pulse wave velocity (PWV), as an index of aortic stiffness. Design.  Cross-sectional study. Setting.  Outpatient hypertension clinic. Subjects.  Seventy patients with mild-to-moderate essential hypertension, aged 42 ± 8 years, never pharmacologically treated. All subjects underwent routine laboratory tests, 24-h ambulatory blood pressure (BP) monitoring, measurement of carotid-femoral PWV, by means of a computerized method, and AER. Results.  Microalbuminuric patients (AER ≥ 20 μg min−1; n = 19), when comp…

AdultMalecardiovascular riskmedicine.medical_specialtyarterial hypertensionAmbulatory blood pressureSettore MED/09 - Medicina Internamicroalbuminuriapulse wave velocityDiastoleEssential hypertensionRisk FactorsInternal medicineInternal MedicinemedicineAlbuminuriaHumansaortic stiffness;arterial hypertension;cardiovascular risk;microalbuminuria;pulse wave velocityRisk factorPulsePulse wave velocityAortaSettore MED/14 - NefrologiaProteinuriabusiness.industryaortic stiffneBlood Pressure Monitoring AmbulatoryMiddle Agedmedicine.diseaseSettore MED/11 - Malattie Dell'Apparato CardiovascolareElasticityFemoral ArteryEndocrinologyCarotid ArteriesCross-Sectional StudiesHypertensionCardiologyRegression AnalysisMicroalbuminuriaFemalemedicine.symptombusinessBody mass indexBlood Flow Velocity
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Static magnetic fields generated by a 0.5T MRI unit affects in vitro expression of activation markers and interleukin release in human peripheral blo…

2001

To investigate the effects of the static magnetic field (SMF) generated by a 0.5 T superconducting MRI unit on in vitro activation marker expression and interleukin release in human peripheral blood mononuclear cell (PBMC) samples from healthy volunteers.PBMC samples were split into two groups: exposed and sham-exposed under isothermal conditions. PBMC were exposed for 2 h at 24 degrees C to the SMF of a 0.5 T superconducting MRI unit. Immediately after exposure, both samples were cultured for 24 h at 37 degrees C with or without mitogenic stimulation by phytohaemagglutinin (PHA). PBMC were examined for expression of CD25, CD69 and CD71 by immunofluorescence analysis and supernatants were a…

AdultMalechemical and pharmacologic phenomenaBiologyLymphocyte ActivationImmunofluorescencePeripheral blood mononuclear cellBlood cellInterferon-gammaMagneticsAntigens CDmedicineHumansRadiology Nuclear Medicine and imagingIL-2 receptorPhytohemagglutininsCells CulturedPhytohaemagglutininRadiological and Ultrasound Technologymedicine.diagnostic_testCD69Interleukinhemic and immune systemsMagnetic Resonance ImagingMolecular biologyStimulation ChemicalIn vitromedicine.anatomical_structureImmunologyLeukocytes Mononuclearbiology.proteinFemaleInterleukin-4BiomarkersInternational Journal of Radiation Biology
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Hamartoma of the urinary bladder: case report and review of the literature.

1999

Bladder hamartoma is a rare benign entity with only eight cases reported in the literature thus far, and whose general imaging features have not, to our knowledge, been previously discussed. The purpose of this report is to review the literature and to discuss the imaging findings in one case of bladder hamartoma where US features were those of an inhomogeneous solid mass with an unechogenic center, which was in accordance with the CT findings of a soft tissue mass with central inhomogeneous enhancement due to central necrosis.

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesPathologymedicine.medical_specialtyHamartomaUrinary BladderCentral necrosisCystectomyDiagnosis DifferentialMedicineSoft tissue massHamartomaHumansRadiology Nuclear Medicine and imagingCt findingsNeuroradiologyUltrasonographyUrinary bladdermedicine.diagnostic_testbusiness.industryUrinary Bladder DiseasesSolid massInterventional radiologyGeneral Medicinemedicine.diseasemedicine.anatomical_structureRadiologybusinessTomography X-Ray ComputedEuropean radiology
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Abnormal Somatosensory Evoked Potentials Indicate Compressive Cervical Myelopathy in Mucopolysaccharidoses

2000

Compressive myelopathy at the cranio-cervical junction is a complication of mucopolysaccharidoses (MPS). To detect cervical myelopathy we recorded median and posterior tibial nerve SEPs in 15 patients aged 2.4 - 33.4 years (median 8.8 years) with MPS I-S (n = 3), MPS IVA (n = 8) and MPS VI (n = 4). In addition to the cortical waveforms we recorded the subcortical median nerve SEPs N13b and P13 generated near the cranio-cervical junction and the lemniscal P30 after posterior tibial nerve stimulation. MRI studies in 13 subjects revealed spinal cord compression at the cranio-cervical junction in 10 patients; 5 patients had an increased signal intensity on the T2-weighted initial MRI indicating…

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesmedicine.medical_specialtyAdolescentSensitivity and SpecificityCentral nervous system diseaseMyelopathySpinal cord compressionEvoked Potentials SomatosensorymedicineHumansChildbusiness.industryGeneral MedicineCervical cord compressionMucopolysaccharidosesmedicine.diseaseSpinal cordMagnetic Resonance ImagingMedian nerveMedian NerveSurgerybody regionsmedicine.anatomical_structureSpinal CordSomatosensory evoked potentialChild PreschoolPediatrics Perinatology and Child HealthFemaleNeurology (clinical)RadiologyTibial NervebusinessSpinal Cord CompressionMyelomalaciaNeckNeuropediatrics
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