Search results for "Dog"

Prymat Papieża

2015

Problematyka teologicznego uzasadnienia urzędu papieskiego obejmuje tradycyjnie trzy pytania: Czy Jezus w osobie Piotra założył urząd uniwersalnej jedności Kościoła (petrinitas)? Czy istnieje sukcesja tego urzędu począwszy od Piotra po dzień dzisiejszy (perpetuitas)? Wjaki sposób urząd Piotra wiąże się z Rzymem jako miejscem jego sprawowania (romanitas)? W artykule przedstawiono nowe koncepcje teologiczne dotyczące prymatu papieża, biorąc pod uwagę obraz Piotra w Nowym Testamencie oraz proces rozwoju urzędu papieskiego w postaci prymatu biskupa Rzymu. Wostatniej części przedłożenia nakreślono perspektywę ekumeniczną, rozpatrywaną na tle teologicznych i magisterialnych wypowiedzi na temat ro…

Early evolutionary colocalization of the nuclear ribosomal 5S and 45S gene families in seed plants: evidence from the living fossil gymnosperm Ginkgo…

2012

In seed plants, the colocalization of the 5S loci within the intergenic spacer (IGS) of the nuclear 45S tandem units is restricted to the phylogenetically derived Asteraceae family. However, fluorescent in situ hybridization (FISH) colocalization of both multigene families has also been observed in other unrelated seed plant lineages. Previous work has identified colocalization of 45S and 5S loci in Ginkgo biloba using FISH, but these observations have not been confirmed recently by sequencing a 1.8 kb IGS. In this work, we report the presence of the 45S–5S linkage in G. biloba, suggesting that in seed plants the molecular events leading to the restructuring of the ribosomal loci are much o…

L’affresco con la Virgo lactans “in maestà” e la Trinità tricefala: un’opera castigliana?

2023

Nel saggio si approfondisce la lettura iconografica di un affresco tardo-gotico dell'ultimo quarto del XV secolo conservato nella chiesa di Santa Maria la Porta di Geraci Siculo (PA). La Madonna che allatta il Bambino, il tipo di trono architettonico in cui è posta e la presenza della rara iconografia della Trinità tricefala suggeriscono una matrice iberica, probabilmente castigliana The essay explores the iconographic interpretation of a late Gothic fresco from the last quarter of the 15th century preserved in the church of Santa Maria la Porta in Geraci Siculo (PA). The Madonna suckling the Child, the type of architectural throne on which she is placed and the presence of the rare iconogr…

Perception of pathogenic or beneficial bacteria and their evasion of host immunity: pattern recognition receptors in the frontline

2015

International audience; Plants are continuously monitoring the presence of microorganisms to establish an adapted response. Plants commonly use pattern recognition receptors (PRRs) to perceive microbe- or pathogen-associated molecular patterns (MAMPs/PAMPs) which are microorganism molecular signatures. Located at the plant plasma membrane, the PRRs are generally receptor-like kinases (RLKs) or receptor-like proteins (RLPs). MAMP detection will lead to the establishment of a plant defense program called MAMP-triggered immunity (MTI). In this review, we overview the RLKs and RLPs that assure early recognition and control of pathogenic or beneficial bacteria. We also highlight the crucial func…

Impact of Platelet Reactivity in ACS Patients on Clinical Outcomes with Triple Antithrombotic Therapy

2021

Optimal antithrombotic therapy after percutaneous coronary intervention (PCI) in patients on oral anticoagulants (OAC) remains a clinical conundrum. In fact, combining an OAC with dual antiplatelet therapy (triple antithrombotic therapy, TAT) increases the risk of bleeding. Clopidogrel is the only thienopyridine recommended in TAT patients. Whether its response plays a relevant role in this setting remains uncertain. We aimed to evaluate the level of platelet reactivity inhibition (PRI) achieved by oral TAT in Acute Coronary Syndrome (ACS) patients undergoing PCI and its relationship with outcomes. We performed a multicenter prospective observational study and assessed PRI by vasodilator-st…

Nuovi scenari della formazione docenti. Atteggiamenti didattico-multimediale: una possibile strategia verso tecniche di inclusione e prevenzione del …

il lavoro si propone di riflettere su come i docenti della scuola odierna possano attivare strategie di inclusione e prevenzione del disagio cybersociale mediante l'applicazione della didattica multimediale e l'interconnessione, attraverso l'uso di nuove modalità relazionali in presenza quali la peer professionals education, il cui risultato sfocia nel rispetto dell'alterità incluisiva

Editoriale

2008

Genome degeneration and adaptation in a nascent stage of symbiosis

2014

Symbiotic associations between animals and microbes are ubiquitous in nature, with an estimated 15% of all insect species harboring intracellular bacterial symbionts. Most bacterial symbionts share many genomic features including small genomes, nucleotide composition bias, high coding density, and a paucity of mobile DNA, consistent with long-term host association. In this study, we focus on the early stages of genome degeneration in a recently derived insect-bacterial mutualistic intracellular association. We present the complete genome sequence and annotation of Sitophilus oryzae primary endosymbiont (SOPE). We also present the finished genome sequence and annotation of strain HS, a close…

Explaining local governments' cost efficiency: Controllable and uncontrollable factors

2020

Abstract Efficient and effective management of public resources is essential at all levels of government. This issue has gained momentum due to the strains that affected public sector finances after the onset of the 2007/08 crisis in many countries, particularly in Europe. In this article, we evaluate the influence of environmental variables that affect local government efficiency in one European country, Spain, during the crisis years (2009–2015). To this end, and considering the possible influence of both controllable and uncontrollable factors, we use an approach that is able to analyse their impact across the conditional distribution of performance, and which controls for the (likely) e…

Rac1 and PAK1 are upstream of IKK-ε and TBK-1 in the viral activation of interferon regulatory factor-3

2004

The anti-viral type I interferon (IFN) response is initiated by the immediate induction of IFN beta, which is mainly controlled by the IFN-regulatory factor-3 (IRF-3). The signaling pathways mediating viral IRF-3 activation are only poorly defined. We show that the Rho GTPase Rac1 is activated upon virus infection and controls IRF-3 phosphorylation and activity. Inhibition of Rac1 leads to reduced IFN beta promoter activity and to enhanced virus production. As a downstream mediator of Rac signaling towards IRF-3, we have identified the kinase p21-activated kinase (PAK1). Furthermore, both Rac1 and PAK1 regulate the recently described IRF-3 activators, I kappa B kinase- and TANK-binding kina…