Search results for "Dome"
showing 10 items of 2031 documents
Sustainable growth of EU economies and Baltic context: Characteristics and modelling
2017
The united general growth strategy for all EU Member States, a common economic and political vision as well as location in the same geographic region provides a necessary basis for the benchmarking modelling of economies. The main objective of this study is determination of the functional regularities and drivers of the growth of EU economies and the context of the Baltic States in line with the general trend of the EU, as well as development of the growth model, which can be used for sustainable planning and prediction. Analysis of several regularly published analytical indexes suggests a thesis on innovation as the real basic driving force for EU economies and outlines Innovation Performa…
Sirenomelia, case report and review of the literature.
2020
We present a case of sirenomelia diagnosed in the first trimester of pregnancy. The ultrasound examination showed fused lower extremities and an anechoic structure in the lower abdomen that is clue in the early diagnosis. The postmortem study showed the existence of a single umbilical artery (vitelline artery), with an origin in the abdominal aorta. This finding not only explained the presence of a vascular steal with subsequent underdeveloped of pelvic organs, but also differentiated this condition from caudal regression syndrome.
Microbial strategies to exploit host cells
2005
The European Research Conference (EURESCO) on Spatial and Temporal Dynamics of the Endomembrane System was held in sunny San Feliu de Guixols, Spain, between 16 and 21 October 2004. The conference was organized by D. Holden and H. Stenmark ![][1] By bringing together scientists from the fields of microbiology and cell biology, the European Research Conference (EURESCO) on ‘Spatial and Temporal Dynamics of the Endomembrane System’ combined the best of both worlds at the intersection where intracellular pathogens and host cells meet. The mixture of studies, which focused on the molecular mechanisms behind endocytic and secretory transport, and the pathogenic microbes that exploit these pathwa…
Aizsardzība pret piespiedu darbu starptautiskajās un Latvijas tiesībās.
2020
Piespiedu darbs ir plaši izplātīts cilvēktiesību aizskārums. Cīņa ar piespiedu darbu ir globāls izaicinājums, jo mūsdienās no šī cilvēktiesību aizskāruma cieš apmēram 25 miljoni cilvēku. Tas nozīme, ka, šobrīd, viens no 300 cilvēkiem ir spiests nodarboties ar piespiedu darbu. Bakalaura darba “Aizsardzība pret piespiedu darbu starptautiskajās un Latvijas tiesībās” mērķis ir izpētīt starptautiskās saistības un starptautiskos dokumentus, kas attiecas uz piespiedu darbu. Noteikt piespiedu darba jēdziena saturu, kā arī izanalizēt Latvijas piespiedu darba regulējumu. Ir svarīgi, lai normatīvais regulējums attīstītos arī turpmāk, lai cilvēku pamattiesību aizsardzība būtu pilnvērtīgāka, bet starpta…
Semantiskās makrostruktūras rakstos par Maltas prezidentūru Eiropas Savienības Padomē
2017
Kognitīvās psiholoģijas pētījumi izceļ tematu kā galveno teksta elementu, ko cilvēka prāts atceras, tādēļ ziņu rakstu par politiski nozīmīgiem notikumiem, kā ES prezidentūra, semantiskās makrostruktūras norāda uz šī notikuma prioritātēm un veido sabiedrības viedokli par apspriestajiem jautājumiem. Šī pētījuma mērķis ir apskatīt ziņu rakstu par Maltas prezidentūru ES Padomē semantiskās makrostruktūras ar diskursa analīzes palīdzību un novērtēt Padomes izvirzīto prioritāšu atbilstību tēmām, kas tiek minētas prezidentūras oficiālajā tīmekļa vietnē publicētajos rakstos. Pētījuma rezultāti liecina, ka vairākums rakstos iekļauto semantisko makrostruktūru attiecas uz ES administrāciju, migrāciju u…
An entropy-based machine learning algorithm for combining macroeconomic forecasts
2019
This paper applies a Machine Learning approach with the aim of providing a single aggregated prediction from a set of individual predictions. Departing from the well-known maximum-entropy inference methodology, a new factor capturing the distance between the true and the estimated aggregated predictions presents a new problem. Algorithms such as ridge, lasso or elastic net help in finding a new methodology to tackle this issue. We carry out a simulation study to evaluate the performance of such a procedure and apply it in order to forecast and measure predictive ability using a dataset of predictions on Spanish gross domestic product.
Gradual caldera collapse at Bardarbunga volcano, Iceland, regulated by lateral magma outflow
2016
Large volcanic eruptions on Earth commonly occur with a collapse of the roof of a crustal magma reservoir, forming a caldera. Only a few such collapses occur per century, and the lack of detailed observations has obscured insight into the mechanical interplay between collapse and eruption.We usemultiparameter geophysical and geochemical data to show that the 110-square kilometer and 65-meter-deep collapse of Bárdarbunga caldera in 2014–2015 was initiated through withdrawal of magma, and lateral migration through a 48-kilometers-long dike, from a 12-kilometers deep reservoir. Interaction between the pressure exerted by the subsiding reservoir roof and the physical properties of the subsurfac…
Simultaneous determination of different classes of antibiotics in fish and livestock by CE-MS
2007
A specific CE-MS method was developed for the simultaneous determination of 12 antibacterial residues (four sulfonamides: sulfamethazine, sulfathiazole, sulfadiazine, and sulfachlorpyridazine; four beta-lactams: amoxicillin, ampicillin, oxacillin, and penicillin V, and four quinolones: danofloxacin, enrofloxacin, ofloxacin, and flumequine) in fish and livestock. Separation conditions, sheath liquid composition and electrospray parameters were optimized to obtain adequate CE separation and a high sensitivity. CE employed a 75 cm long fused-silica capillary (50 cm thermostated plus 25 cm at room temperature) 75 microm id and a 60 mM ammonium acetate separation buffer at pH 8 with 10% of metha…
EGFR signalling is required for Paracentrotus lividus endomesoderm specification
2008
The EGFR pathway is critical for cell fate specification throughout the development of several organisms. Here we identified in sea urchin an EGFR-related antigen maternally expressed and showing a dynamic pattern of localization during development. To investigate the role played by the EGFR in Paracentrotus lividus development we blocked its activity by using the EGFR kinase inhibitor AG1478. This treatment produces decrease of EGFR phosphorylation, and embryos with various defects especially in the endomesoderm territory until to obtain an animalized phenotype. These effects are rescued by the addition of TGF-alpha, an EGFR ligand. The role played by EGFR-like along the animal/vegetal axi…
The effects of ergot and non-ergot-derived dopamine agonists in an experimental mouse model of endometriosis
2011
Implantation of a retrogradely shed endometrium during menstruation requires an adequate blood supply, which allows the growth of endometriotic lesions. This suggests that the development of endometriosis can be impaired by inhibiting angiogenesis. The growth of endometriotic foci is impaired by commercial oncological antiangiogenic drugs used to block vascular endothelial growth factor (VEGF) signaling. The dopamine agonist cabergoline (Cb2) inhibits the growth of established endometriosis lesions by exerting antiangiogenic effects through VEGFR2 inactivation. However, the use of ergot-derived Cb2 is associated with an increased incidence of cardiac valve regurgitation. To evaluate the pot…