Search results for "Dons"

showing 10 items of 190 documents

Investigating REPAIRv2 as a Tool to Edit CFTR mRNA with Premature Stop Codons

2020

Cystic fibrosis (CF) is caused by mutations in the gene encoding the transmembrane conductance regulator (CFTR) protein. Some CF patients are compound heterozygous or homozygous for nonsense mutations in the CFTR gene. This implies the presence in the transcript of premature termination codons (PTCs) responsible for a truncated CFTR protein and a more severe form of the disease. Aminoglycoside and PTC124 derivatives have been used for the read-through of PTCs to restore the full-length CFTR protein. However, in a precision medicine framework, the CRISPR/dCas13b-based molecular tool &ldquo

congenital hereditary and neonatal diseases and abnormalitiesRNA editingMutantNonsense mutationSettore BIO/11 - Biologia MolecolareBiologyCRISPR/dCas13bCatalysislcsh:Chemistrycystic fibrosisInorganic ChemistryGuide RNASettore BIO/06 - Anatomia Comparata E CitologiaPhysical and Theoretical Chemistrylcsh:QH301-705.5Molecular BiologyGeneSpectroscopyMessenger RNApremature termination codons (PTCs)Organic ChemistryGeneral Medicinerespiratory systemStop codonTransmembrane proteinrespiratory tract diseasesComputer Science ApplicationsCell biologySettore BIO/18 - Geneticalcsh:Biology (General)lcsh:QD1-999RNA editingInternational Journal of Molecular Sciences
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Communication-Efficient Federated Learning in Channel Constrained Internet of Things

2022

Federated learning (FL) is able to utilize the computing capability and maintain the privacy of the end devices by collecting and aggregating the locally trained learning model parameters while keeping the local personal data. As the most widely-used FL framework,Jederated averaging (FedAvg) suffers an expensive communication cost especially when there are large amounts of devices involving the FL process. Moreover, when considering asynchronous FL, the slowest device becomes the bottleneck for the cask effect and determines the overall latency. In this work, we propose a communication-efficient federated learning framework with partial model aggregation (CE-FedPA) algorithm to utilize comp…

data privacytietosuojatrainingkoneoppiminenfederated learningcostssimulointiesineiden internetsimulationtiedonsiirtoperformance evaluationdata integrity
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Mechanical Coupling Between Muscle-Tendon Units Reduces Peak Stresses

2017

The presence of mechanical linkages between synergistic muscles and their common tendons may distribute forces among the involved structures. We review studies, using humans and other animals, examining muscle and tendon interactions and discuss the hypothesis that connections between muscle bellies and within tendons may serve as a mechanism to distribute forces and mitigate peak stresses. peerReviewed

displacementmusculoskeletal diseasesMaterials scienceinjurylihaksetPhysical Therapy Sports Therapy and RehabilitationStrain (injury)sidekudoksetTendonsjänteet03 medical and health sciencesstrain0302 clinical medicineTendon InjuriesmedicineAnimalsHumansOrthopedics and Sports Medicineskeletal muscleMuscle Skeletalconnective tissuerasitusAchilles tendonforce transmissionSkeletal muscle030229 sport sciencesmusculoskeletal systemmedicine.diseaseTendonCoupling (electronics)Mechanism (engineering)Achilles tendonmedicine.anatomical_structureStress Mechanicalkantajännevammat030217 neurology & neurosurgeryMuscle ContractionBiomedical engineeringExercise and Sport Sciences Reviews
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Imaging of long head biceps tendon. A multimodality pictorial essay

2019

The aim of this article is to provide an imaging review of normal anatomy, most common anatomical variants and pathologies of the long head of the biceps tendon (LHB) encountered during the daily practice. (www.actabiomedica.it).

endocrine systemShoulder JointReviewMRMultimodal ImagingTendon InjurieTendonsArthroscopyTendon InjuriesMR-ArthrographyHumansLHBShoulder InjuriesHuman
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Spectrum and energy efficient solutions for OFDMA collaborative wireless networks

2013

energiatehokkuusradio resource allocationcollaborative mobile cloudspektritehokkuuscooperative communicationsrelaytoistimetspectrum efficiencyOFDMAlangaton tiedonsiirtopilvipalvelutmobiililaitteetenergy efficiencylangattomat verkot
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Transmission Optimization and Resource Allocation for Wireless Powered Dense Vehicle Area Network With Energy Recycling

2022

The wireless-powered communication paradigm brings self-sustainability to the on-vehicle sensors by harvesting the energy from radiated radio frequency (RF) signals. This paper proposes a novel transmission and resource allocation strategy for the scenario where multiple wireless powered vehicle area networks (VAN) co-existed with high density. The considered multi-VAN system consists of a remote master access point (MAP), multiple on-vehicle hybrid access points (HAPs) and sensors. Unlike previous works, we consider that the sensors can recycle the radiated radio frequency energy from all the HAPs when HAPs communicate with MAP, so the dedicated signals for energy harvesting (EH) are unnec…

energy harvestingComputer Networks and Communicationskulkuneuvotekniikkasensoriverkotdense networkAerospace Engineeringresursointienergian kerääminenwireless powered networklangaton tiedonsiirtooptimointithroughput maximizationAutomotive EngineeringElectrical and Electronic Engineeringlangattomat verkotIEEE Transactions on Vehicular Technology
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Tiedonsiirto ennustamalla

2017

Tiedon tuottaminen ja siirto on tulevaisuudessa merkittävässä osassa kaikkea verkkoliikennettä. Ennusteiden mukaan sekä laitteiden että kerätyn tiedon määrä moninker- taistuu tulevaisuudessa. Tämä aiheuttaa haasteita laitteille ja tiedon siirtoverkoille. Tässä tut- kielmassa selvitetään, voidaanko tiedon ennustamisella säästää resursseja niin siirtokanavien kuin laitteiden osalta. Ennustamisessa hyödynnetään konetunnistamisen menetelmiä ja mal- lia simuloidaan oikealla tiedolla. Production and transfer of information will constitute a substantial part of all network traffic in the future. According to estimates, the amount of equipment as well as the amount of information gathered will multi…

ennustaminentiedonhallintasignaalinsiirtotiedonkäsittelytiedonsiirtoTiedonkeruutiedonhankinta
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UAV-Aided Secure Short-Packet Data Collection and Transmission

2023

Benefiting from the deployment flexibility and the line-of-sight (LoS) channel conditions, unmanned aerial vehicle (UAV) has gained tremendous attention in data collection for wireless sensor networks. However, the high-quality air-ground channels also pose significant threats to the security of UAV aided wireless networks. In this paper, we propose a short-packet secure UAV-aided data collection and transmission scheme to guarantee the freshness and security of the transmission from the sensors to the remote ground base station (BS). First, during the data collection phase, the trajectory, the flight duration, and the user scheduling are jointly optimized with the objective of maximizing t…

finite blocklengthdata collectionsecure transmissionInternet of Thingseavesdroppingsensoriverkotresource allocationshort-packet transmissionlangaton tekniikkamiehittämättömät ilma-aluksetsensorstiedonsiirtodatatietoliikennetrajectoryunmanned aerial vehicleesineiden internetElectrical and Electronic Engineeringautonomous aerial vehicleswireless sensor networksIEEE Transactions on Communications
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Exploration of muscle–tendon biomechanics one year after Achilles tendon rupture and the compensatory role of flexor hallucis longus

2023

Achilles tendon (AT) rupture leads to long-term structural and functional impairments. Currently, the predictors of good recovery after rupture are poorly known. Thus, we aimed to explore the interconnections between structural, mechanical, and neuromuscular parameters and their associations with factors that could explain good recovery in patients with non-surgically treated AT rupture. A total of 35 patients with unilateral rupture (6 females) participated in this study. Muscle-tendon structural, mechanical, and neuromuscular parameters were measured 1-year after rupture. Interconnections between the inter-limb differences (Δ) were explored using partial correlations, followed by multivar…

functionmuscleRehabilitationBiomedical EngineeringBiophysicslihaksetultrasonographyjänteetultraäänitutkimusOrthopedics and Sports Medicinemechanicalvammatbiomekaniikkakantajänneflexor hallucis longus muscletendons
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O dom entre História e Antropologia. Figuras medievais do doador

2003

RésuméL'ouverture bénéfique de l'histoire envers l'anthropologie, pose la question de l'usage par la médiévistique de modèles anthropologiques pas toujours opérants pour expliquer la société médiévale. Le problème étant particulièrement sensible en ce qui concerne le don aux établissements ecclésiastiques. Dans la perspective d'une compréhension générale de cette pratique sociale présente pendant tout le Moyen Âge, l'enquête sur la figure du donateur dans les inscriptions épigraphiques (VIe-XIIe s.) révèle des traits d'un système complexe d'enchaînements entre l'ici-bas et l'au-delà: inversion et déplacement de rôles, intermédiation, circulation et duplicité des biens et des acteurs. Abstra…

fêtesMoyen Age[ SHS.HIST ] Humanities and Social Sciences/Historyidentité (banquetsCroyances et représentationshistoriacostume..)adoubementviolencehistoirecadeaux et donsparaîtrechassesdoador[SHS.ANTHRO-SE] Humanities and Social Sciences/Social Anthropology and ethnologyRitestournoisIdade Médiadonateur[SHS.ANTHRO-SE]Humanities and Social Sciences/Social Anthropology and ethnologyéchangesanthropologieantropologia[ SHS.ANTHRO-SE ] Humanities and Social Sciences/Social Anthropology and ethnologyBilans historiographiques et perspectives critiques[SHS.HIST] Humanities and Social Sciences/Historydom[SHS.HIST]Humanities and Social Sciences/Historydon
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