Search results for "Dote"

showing 10 items of 164 documents

Infiammazione, stress ossidativo ed attivazione endoteliale: confronto tra pazienti uremici in trattamento sostitutivo e pazienti con insufficienza r…

2005

Infiammazione stress ossidativo attivazione endoteliale insufficienza renale cronica
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Relazione tra fetuina-A, filtrato glomerulare (GFR) e disfunzione endoteliale in pazienti ipertesi con insufficienza renale cronica di grado moderato…

2009

Insufficienza renale cronicafetuina-Adisfunzione endoteliale
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Essential Hypertension: Elastase, Nitric Oxide Metabolites and Oxidative Status.

2008

Ipertensione arteriosa disfunzione endoteliale stress ossidativo
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Effect of nut consumption on oxidative stress and the endothelial function in metabolic syndrome

2010

Effect of nut consumption on oxidative stress and the endothelial function in metabolic syndrome BACKGROUND & AIMS: Oxidative stress has a key role in atherosclerosis, cancer and other chronic diseases. Some bioactive compounds in nuts have been implicated in antioxidant activities. OBJECTIVE: We assessed how nut consumption affected several markers of oxidation and endothelial function (EF) in metabolic syndrome (MetS) patients. PATIENTS AND METHODS: A randomized, controlled, parallel feeding trial was conducted on 50 MetS adults who were recommended a healthy diet supplemented or not with 30 g of mixed nuts (Nut and Control groups, respectively) every day for 12 weeks. The plasma anti…

MaleAntioxidantmedicine.medical_treatmentantioxidant capacityIsoprostanesCritical Care and Intensive Care Medicinemedicine.disease_causeAntioxidantsLipid peroxidationchemistry.chemical_compoundendothelial functionMedicineNutschemistry.chemical_classificationMetabolic SyndromeBioquímica y tecnologíaNutrition and Dieteticsdigestive oral and skin physiologyfood and beveragesArteriesMiddle Aged0261-5614Lipoproteins LDLBiochemistry and technologymedicine.anatomical_structure8-Hydroxy-2'-DeoxyguanosineFatty Acids UnsaturatedPolyunsaturated fatty acidAdultmedicine.medical_specialtyEndotheliumAdolescentDNA damageEstrès oxidatiuFruita seca -- Aspectes nutritiusBioquímica i biotecnologiaYoung AdultLipid oxidationInternal medicineHumansAgedbusiness.industryDeoxyguanosineEndoteli vascularmedicine.diseaseDietOxidative StressEndocrinologychemistryDNA damageVascular ResistanceEndothelium VascularMetabolic syndromebusinessOxidative stressBiomarkers
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[Gadolinium-containing contrast agents: Gadoterat-meglumine is safe in patients with chronic renal failure].

2014

Objective To prospectively compare the renal safety of meglumine gadoterate (Gd-DOTA)-enhanced magnetic resonance imaging (MRI) to a control group (unenhanced MRI) in high-risk patients. Methods Patients with chronic kidney disease (CKD) scheduled for MRI procedures were screened. The primary endpoint was the percentage of patients with an elevation of serum creatinine levels, measured 72 ± 24 h after the MRI procedure, by at least 25 % or 44.2 μmol/l (0.5 mg/dl) from baseline. A non-inferiority margin of the between-group difference was set at −15 % for statistical analysis of the primary endpoint. Main secondary endpoints were the variation in serum creatinine and eGFR values between base…

MaleDrug-Related Side Effects and Adverse ReactionsContrast MediaAcute Kidney InjuryMeglumine gadoterateMagnetic Resonance ImagingNephrogenic Fibrosing DermopathyHeterocyclic CompoundsGd-DOTANephrogenic systemic fibrosisOrganometallic CompoundsHumansFemaleRenal Insufficiency ChronicGadolinium-based contrast agent-induced nephropathyMRIRoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin
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Polymorphisms in endothelin system genes, arsenic levels and obesity risk.

2015

Background/objectivesObesity has been linked to morbidity and mortality through increased risk for many chronic diseases. Endothelin (EDN) system has been related to endothelial function but it can be involved in lipid metabolism regulation: Receptor type A (EDNRA) activates lipolysis in adipocytes, the two endothelin receptors mediate arsenic-stimulated adipocyte dysfunction, and endothelin system can regulate adiposity by modulating adiponectin activity in different situations and, therefore, influence obesity development. The aim of the present study was to analyze if single nucleotide polymorphisms (SNPs) in the EDN system could be associated with human obesity.Subjects/methodsWe analyz…

MaleEspañaObesidad:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Fat Distribution::Adiposity [Medical Subject Headings]Endothelins:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]:Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Endothelins [Medical Subject Headings]Polymorphism (computer science)Risk Factors:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity [Medical Subject Headings]:Chemicals and Drugs::Inorganic Chemicals::Elements::Arsenic [Medical Subject Headings]:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]education.field_of_studyMultidisciplinary:Diseases::Pathological Conditions Signs and Symptoms::Pathologic Processes::Disease Attributes::Chronic Disease [Medical Subject Headings]Genètica humanaEndothelinsQRMiddle AgedPrognosisReceptor Endothelin APolimorfismo de nucleótido único:Anatomy::Cells::Connective Tissue Cells::Adipocytes [Medical Subject Headings]ObesitatMedicineFemaleTomografía computarizada por rayos X:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]Endothelin receptor:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Imaging::Image Interpretation Computer-Assisted::Tomography X-Ray Computed [Medical Subject Headings]Research Articlemedicine.hormonemedicine.medical_specialtyGenotype:Phenomena and Processes::Mathematical Concepts::Probability::Risk [Medical Subject Headings]SciencePopulationSingle-nucleotide polymorphism:Phenomena and Processes::Metabolic Phenomena::Metabolism::Lipid Metabolism::Lipolysis [Medical Subject Headings]BiologyPolymorphism Single NucleotideArsenicReceptores de endotelinasInternal medicineAdipocitos:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors Peptide::Receptors Endothelin [Medical Subject Headings]medicineHumansGenetic Predisposition to DiseaseObesityeducation:Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism Genetic::Polymorphism Single Nucleotide [Medical Subject Headings]AdiponectinHaplotypeEnfermedad crónicamedicine.diseaseObesityEndocrinologyHaplotypesSpain:Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Adipokines::Adiponectin [Medical Subject Headings]GenotipoFollow-Up StudiesArsénicoPLoS ONE
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Cohort Differences in Maximal Physical Performance: A Comparison of 75- and 80-Year-Old Men and Women Born 28 Years Apart

2020

Abstract Background Whether increased life expectancy is accompanied by increased functional capacity in older people at specific ages is unclear. We compared similar validated measures of maximal physical performance in 2 population-based older cohorts born and assessed 28 years apart. Method Participants in the first cohort were born in 1910 and 1914 and were assessed at age 75 and 80 years, respectively (N = 500, participation rate 77%). Participants in the second cohort were born in 1938 or 1939 and 1942 or 1943 and were assessed at age 75 and 80 years, respectively (N = 726, participation rate 40%). Participants were recruited using a population register and all community-dwelling pers…

Malerip strengthAgingVital capacityWalkingfunctional capacityIsometric exerciseGrip strengthpulmonary function testbirth0302 clinical medicineMedicine030212 general & internal medicinesecular trendskohorttitutkimusFinlandAged 80 and overbirth cohortseducation.field_of_studyHand Strengthpulmonary functionPhysical Functional PerformanceRespiratory Function TestskävelyCohortrespiratory physiologycommunityFemaleikääntyneetelinajanodoteextension of kneePopulationfyysinen toimintakykywalking speed03 medical and health sciencesFEV1/FVC ratiophysical functionforced vital capacitytoimintakykyHumanssolder adulteducationGeriatric AssessmentAgedsuorituskykybusiness.industryPreferred walking speedlife expectancyLife expectancyforced expiratory volume functionGeriatrics and Gerontologybusiness030217 neurology & neurosurgeryDemographyThe Journals of Gerontology: Series A
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Combined thermodynamic and rare earth element modelling of garnet growth during subduction: Examples from ultrahigh-pressure eclogite of the Western …

2008

Abstract Major and trace element zonation patterns were determined in ultrahigh-pressure eclogite garnets from the Western Gneiss Region (Norway). All investigated garnets show multiple growth zones and preserve complex growth zonation patterns with respect to both major and rare earth elements (REE). Due to chemical differences of the host rocks two types of major element compositional zonation patterns occur: (1) abrupt, step-like compositional changes corresponding with the growth zones and (2) compositionally homogeneous interiors, independent of growth zones, followed by abrupt chemical changes towards the rims. Despite differences in major element zonation, the REE patterns are almost…

MineralRare-earth elementTrace elementGeochemistryMetamorphismEpidoteengineering.materialGeophysicsSpace and Planetary ScienceGeochemistry and PetrologyEarth and Planetary Sciences (miscellaneous)engineeringEclogiteGeologyAmphiboleGneissEarth and Planetary Science Letters
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Fluid migration above a subducted slab - Thermodynamic and trace element modelling of fluid-rock interaction in partially overprinted eclogite-facies…

2011

Abstract The amount and composition of subduction zone fluids and the effect of fluid–rock interaction at a slab–mantle interface have been constrained by thermodynamic and trace element modelling of partially overprinted blueschist-facies rocks from the Sesia Zone (Western Alps). Deformation-induced differences in fluid flux led to a partial preservation of pristine mineral cores in weakly deformed samples that were used to quantify Li, B, Sr and Pb distribution during mineral growth, -breakdown and modification induced by fluid–rock interaction. Our results show that Li and B budgets are fluid-controlled, thus acting as tracers for fluid–rock interaction processes, whereas Sr and Pb budge…

MineralSubductionTrace elementGeochemistryEpidoteengineering.materialGeophysicsSpace and Planetary ScienceGeochemistry and PetrologyEarth and Planetary Sciences (miscellaneous)SlabengineeringInstitut für GeowissenschaftenShear zoneGeologyMetamorphic faciesMylonite
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Intracellular glutathione in human hepatocytes incubated with S-adenosyl-L-methionine and GSH-depleting drugs

1991

Abstract The present study was undertaken to investigate (a) whether S- adenosyl- L -methionine (SAMe) added to culture medium can increase intracellular glutathione (GSH) levels in human hepatocytes and (b) whether SAMe can prevent the GSH depletion found in human hepatocytes incubated with GSH-depleting drugs (paracetamol, opiates, ethanol). Incubation of hepatocytes with increasing concentrations of SAMe resulted in a dose-dependent elevation of intracellular GSH content, which reached its maximum (35% increase) at 30 μM after 20 h. SAMe, as the only sulfur source in the medium, was efficient in repleting GSH-depleted hepatocytes following treatment with diethyl maleate. Incubation of hu…

NarcoticsS-Adenosylmethioninemedicine.medical_treatmentPharmacologyToxicologychemistry.chemical_compoundmedicineHumansAntidoteIncubationCells CulturedAcetaminophenEthanolMethionineDose-Response Relationship DrugEthanolGlutathioneGlutathioneHeroinmedicine.anatomical_structureLiverchemistryBiochemistryHepatocyteToxicityMethadoneIntracellularToxicology
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