Search results for "Drug users"
showing 6 items of 16 documents
Evolution of patients’ socio-behavioral characteristics in the context of DAA: Results from the French ANRS CO13 HEPAVIH cohort of HIV-HCV co-infecte…
2018
International audience; BACKGROUND:Direct-acting antivirals (DAA) have dramatically increased HCV cure rates with minimal toxicity in HIV-HCV co-infected patients. This study aimed to compare the socio-behavioral characteristics of patients initiating pegylated-interferon (PEG-IFN)-based HCV treatment with those of patients initiating DAA-based treatment.METHODS:ANRS CO13 HEPAVIH is a national multicenter prospective cohort started in 2005, which enrolled 1,859 HIV-HCV co-infected patients followed up in French hospital outpatient units. Both clinical/biological and socio-behavioral data were collected during follow-up. We selected patients with socio-behavioral data available before HCV tr…
Evolución de la resistencia transmitida y adquirida a fármacos antirretrovirales en pacientes infectados con VIH-1
2018
Introducción: La adquisición y transmisión de resistencia amenaza el éxito del tratamiento antirretroviral. En este estudio evaluamos el comportamiento epidemiológico de las mutaciones de resistencia (MR) a fármacos antirretrovirales del VIH-1 según factores de riesgo y clínicos específicos. Metodología: Este es un estudio retrospectivo observacional de series transversales acumuladas, realizado en la Unidad de Enfermedades Infecciosas de un hospital universitario en España (CHGUV) entre los años 2003 y 2014. Nuestro objetivo fue estimar la evolución de la frecuencia anual de MR a fármacos antirretrovirales en el genoma de la proteasa y transcriptasa inversa del VIH-1 durante el periodo de …
Funcionamiento neuropsicológico en drogodependientes VIH/SIDA inmunodeprimidos: Importancia de la fase de la infección y del consumo de drogas
2000
Todavía no disponemos de factores de riesgo definitivos que permitan predecir la naturaleza y magnitud de las complicaciones neuropsicológicas asociadas a la infección por VIH. Con este trabajo nos planteamos estudiar la naturaleza del deterioro neuropsicológico asociado al VIH en drogodependientes con historia de consumo de drogas por vía intravenosa inmunodeprimidos, así como determinar la influencia que tienen sobre el mismo la fase clínica de la infección (asintomáticolSIDA) y el consumo de drogas. Para ello hemos utilizado una muestra de 20 drogodependientes voluntarios en distintas fases de la infección (A3 y C3). En cada uno de estos grupos la mitad de los sujetos se encuentra en abs…
Burden of HIV and hepatitis C co-infection: the changing epidemiology of hepatitis C in HIV-infected patients in France.
2015
Équipe UB/CHU (EA) Pôle MERS CT3 Hors Enjeu; International audience; Background & AimsTo better evaluate the HIV-HCV co-infection burden in the context of new effective HCV treatment. MethodsWe reviewed all the epidemiological data available on HCV-related disease in HIV-infected patients in France. Sources of data have been selected using the following criteria: (i) prospective cohorts or cross-sectional surveys; (ii) conducted at a national level; (iii) in the HIV-infected population; (iv) able to identify HCV co-infection and chronic active hepatitis C (HCV RNA positive); and (v) conducted during the period 2003-2012. ResultsThe overall prevalence of HIV-HCV co-infection has decreased fr…
The Relationship Between Demographic Variables and Substance Use in Undergraduates
2018
The aim of this study was to explore the relationships between demographic variables and substance use during the last month among undergraduates. A self-administered questionnaire “Students 2004” was distributed among a convenience sample of undergraduates (n = 983; between the ages of 21 and 36) at a large, public university in the south of Poland. The data were analyzed statistically, using chi-squared test, logistic regression, and cluster analysis. The results indicated that excessive alcohol drinking and substance use among students are related to being male, studying social sciences, living in a dorm or apartment, and living in an urban area. Binge drinking is related to gender and l…
Recommendations for the prevention, diagnosis, and treatment of chronic hepatitis B and C in special population groups (migrants, intravenous drug us…
2011
Abstract The global spread of hepatitis B virus (HBV) and hepatitis C virus (HCV), their high chronicity rates and their progression to cirrhosis and hepatocellular carcinoma, are major public health problems. Research and intervention programmes for special population groups are needed in order to assess their infection risk and set up suitable prevention and control strategies. Aim of this paper is to give health care professionals information on HBV and HCV infections amongst migrants, drug users and prison inmates. The manuscript is an official Position Paper on behalf of the following Scientific Societies: Italian Association for the Study of the Liver (A.I.S.F.), Italian Society of In…