Search results for "Drusen"
showing 10 items of 11 documents
Optic disc drusen in tilted disc
2017
Purpose To investigate if a congenital anomaly of the head of the optic nerve like such as tilted disc can be a risk factor for the development of optic disc drusen. Methods The study was performed retrospectively on the files of 47 patients with optic disc drusen. The diagnosis was confirmed by fluorescein angiography and B-scan ultrasonography. The authors examined the fundus photographs and the fluorescein angiographies of these patients looking for the presence of tilted discs. Results Two of the 47 patients with optic nerve drusen had tilted discs as well, about twice the expected rate. Both cases presented a parapapillary hemorrhage. Conclusions The concomitant presence of tilted disc…
Discrimination of retinal images containing bright lesions using sparse coded features and SVM
2015
Diabetic Retinopathy (DR) is a chronic progressive disease of the retinal microvasculature which is among the major causes of vision loss in the world. The diagnosis of DR is based on the detection of retinal lesions such as microaneurysms, exudates and drusen in retinal images acquired by a fundus camera. However, bright lesions such as exudates and drusen share similar appearances while being signs of different diseases. Therefore, discriminating between different types of lesions is of interest for improving screening performances. In this paper, we propose to use sparse coding techniques for retinal images classification. In particular, we are interested in discriminating between retina…
Intravitreal therapies for non-neovascular age-related macular degeneration with intraretinal or subretinal fluid
2017
OBJECTIVE: To evaluate the efficacy of intravitreal therapies in cases of atrophic age-related macular degeneration (AMD) with subretinal or intraretinal fluid. METHODS: A retrospective review was made of the clinical charts of patients diagnosed with atrophic AMD with subretinal or intraretinal fluid. Fundus photographs and spectral-domain optical coherence tomography images were examined, and an analysis was made on the presence of fluid and its density. Neovascularisation was ruled out by fluorescein and/or indocyanine green angiography. RESULTS: The study included 14 eyes from 13 patients with a mean age of 72.64 years and a mean follow-up of 80.5 weeks. Intraretinal fluid was observed …
Kinetic and static perimetry after 16 years and additional OCT-A analysis in eyes with long-lasting optic disc drusen
2021
The aim of the study is to evaluate the progression of visual field (VF) defects over 16 years of observation and to assess abnormalities in vessels and retinal nerve fibre layer (RNFL) thickness in patients with optic disc drusen (ODD). Both static automated perimetry (SAP) and semi-automated kinetic perimetry (SKP) were performed in 16 eyes of 8 patients (mean age 54 years) with ODD among 26 eyes of 13 patients examined 16 years before. The area of I2e, I4e, III4e, and V4e isopters was measured in deg2. The MD and PSD parameters were estimated using SAP. Optical coherence tomography angiography (OCT-A) was additionally performed in 16 ODD eyes and 16 eyes of 8 healthy subjects to estimate…
Prevalence of early and late age-related macular degeneration in India: the INDEYE study.
2010
Purpose.: To estimate the prevalence of early and late age-related macular degeneration (AMD) in India. Methods.: Of 7518 people aged 60 years and older identified from randomly sampled villages in North and South India, 5853 (78%) attended an eye examination including fundus photography. Fundus images were graded according to the Wisconsin Age-Related Maculopathy Grading System. Results.: Fundus images were ungradable in 1587 people, mainly because of cataract. People 80 years of age and older were less likely to attend the eye examination and more likely to have ungradable images. For ages 60 to 79 years, the percent prevalence (95% confidence interval [CI]) were late AMD 1.2 (0.8–1.5); a…
Towards the new spectral-domain optical coherence tomography based classification of age-related macular degeneration
2012
Introducción: La degeneración macular asociada a la edad (DMAE) es un problema sociosanitario de primer orden en las sociedades industrializadas. La aportación de las nuevas técnicas diagnósticas, fundamentalmente la tomografía de coherencia óptica de dominio espectral (SD-OCT), ha ayudado a comprender mejor esta enfermedad. Objetivo: Recordar la clasificación clínica vigente de la DMAE, exponer la nueva clasificación tomográfica de la DMAE exudativa, y revisar los nuevos nuevos hallazgos tomográficos de la degeneración macular seca. Desarrollo: Clásicamente se distinguen dos formas de DMAE: seca y exudativa; asimismo existen tres estadios progresivos de severidad: precoz, intermedio y tard…
Hacia la nueva clasificación de la degeneración macular asociada a la edad basada en la tomografía de coherencia óptica de dominio espectral
2012
Resumen Introduccion La degeneracion macular asociada a la edad (DMAE) es un problema sociosanitario de primer orden en las sociedades industrializadas. La aportacion de las nuevas tecnicas diagnosticas, fundamentalmente la tomografia de coherencia optica de dominio espectral (SD-OCT), ha ayudado a comprender mejor esta enfermedad. Objetivo Recordar la clasificacion clinica vigente de la DMAE, exponer la nueva clasificacion tomografica de la DMAE exudativa, y revisar los nuevos nuevos hallazgos tomograficos de la degeneracion macular seca. Desarrollo Clasicamente se distinguen dos formas de DMAE: seca y exudativa; asimismo existen tres estadios progresivos de severidad: precoz, intermedio y…
Algorithms for the Automated Analysis of Age-Related Macular Degeneration Biomarkers on Optical Coherence Tomography: A Systematic Review
2017
PURPOSE To assess the quality of optical coherence tomography (OCT) grading algorithms for retinal biomarkers of age-related macular degeneration (AMD). METHODS Following a systematic review of the literature data on detection and quantification of AMD retinal biomarkers by available algorithms were extracted and descriptively synthesized. Algorithm quality was assessed using a modified version of the Quality Assessment of Diagnostic Accuracy Studies 2 checklist with a focus on accuracy against established reference standards and risk of bias. RESULTS Thirty five studies reporting computer-aided diagnosis (CAD) tools for qualitative analysis or algorithms for quantitative analysis were iden…
Atrophic Forms (Dry AMD)
2009
Atrophic form of “Dry AMD” is defined by areas of RPE atrophy, often resulting from regression of confluent soft drusen.
Intravitreal ranibizumab for symptomatic drusenoid pigment epithelial detachment without choroidal neovascularization in age-related macular degenera…
2011
Roberto Gallego-Pinazo,1,2 Ana Marina Suelves-Cogollos1, Ester Francés-Muñoz,1 J María Millán,2,3 J Fernando Arevalo,4 J Luis Mullor,5 Manuel Díaz-Llopis,1,2,61Department of Ophthalmology, Hospital Universitario La Fe, Valencia, Spain; 2Centro de Investigación Biomédica en Red de Enfermedades Raras, Valencia, Spain; 3Department of Genetics, Hospital Universitario La Fe, Valencia, Spain; 4Retina and Vitreous Service, Clínica Oftalmológica Centro Caracas, Caracas, Venezuela; 5Unit of Experimental Ophthalmology, Fundación para la Investigación del Hospital Universitario La F…