Search results for "Dual"
showing 10 items of 2547 documents
Rectal cancer: mucinous carcinoma on magnetic resonance imaging indicates poor response to neoadjuvant chemoradiation.
2010
Purpose To assess response of locally advanced rectal carcinoma to chemoradiation with regard to mucinous status and local tumor invasion found at pretherapeutic magnetic resonance imaging (MRI). Methods and Materials A total of 88 patients were included in this prospective study of patients with advanced mrT3 and mrT4 carcinomas. Carcinomas were categorized by MRI as mucinous (mucin proportion >50% within the tumor volume), and as nonmucinous. Patients received neoadjuvant chemoradiation consisting of 50.4 Gy (1.8 Gy/fraction) and 5-fluorouracil on Days 1 to 5 and Days 29 to 33. Therapy response was assessed by comparing pretherapeutic MRI with histopathology of surgical specimens (minimum…
New perspectives on the manipulation of opiate urges and the assessment of cognitive effort associated with opiate urges
2000
Behavioral models of drug urges assume that conditioned urges are strongly associated with drug consumption. An alternative, cognitive model assumes that urges represent the operation of cognitively demanding processes devoted to either supporting or blocking the automatized drug-use behavior. In Study 1, the effect of verbal drug cues and mood induction on self-reported opiate urges were examined. Twenty-four opiate addicts were either instructed to listen to verbal drug cures or neutral cues. Negative mood induction was applied on 12 addicts. Study 2 examined the cognitive processes underlying these urges. In a dual task paradigm, participants responded to a probe stimulus and listened si…
Continuity and discontinuity in memory for threat.
2016
Using a paradigm that allows a quasi-continuous tracking of memory performance over time, two experiments were designed to test the hypotheses that (a) persons with a cognitively avoidant style of coping with threat manifest a dissociation between (intact) short-term and (reduced) long-term retrieval of aversive information and (b) persons with a vigilant coping style recall aversive information particularly well after long retention intervals, provided they are free to think about aversive events. Study 1 (N = 75) showed that avoiders manifest a poor memory for aversive pictures after long retention intervals only. Study 2 (N = 95) replicated this finding. In addition, manipulation of the …
Gray matter network reorganization in multiple sclerosis from 7‐Tesla and 3‐Tesla MRI data
2020
[Objective]: The objective of this study was to determine the ability of 7T‐MRI for characterizing brain tissue integrity in early relapsing‐remitting MS patients compared to conventional 3T‐MRI and to investigate whether 7T‐MRI improves the performance for detecting cortical gray matter neurodegeneration and its associated network reorganization dynamics.
Conscientiousness and Extraversion relate to responsiveness to tempo in dance
2016
Previous research has shown broad relationships between personality and dance, but the relationship between personality and specific structural features of music has not been explored. The current study explores the influence of personality and trait empathy on dancers' responsiveness to small tempo differences between otherwise musically identical stimuli, measured by difference in the amount in acceleration of key joints. Thirty participants were recorded using motion capture while dancing to excerpts from six popular songs that were time-stretched to be slightly faster or slower than their original tempi. Analysis revealed that higher conscientiousness and lower extraversion both correla…
Predicting limiting 'free sugar' consumption using an integrated model of health behavior.
2020
Excess intake of ‘free sugars’ is a key predictor of chronic disease, obesity, and dental ill health. Given the importance of determining modifiable predictors of free sugar-related dietary behaviors, we applied the integrated behavior change model to predict free sugar limiting behaviors. The model includes constructs representing ‘reasoned’ or deliberative processes that lead to action (e.g., social cognition constructs, intentions), and constructs representing ‘non-conscious’ or implicit processes (e.g., implicit attitudes, behavioral automaticity) as predictors of behavior. Undergraduate students (N = 205) completed measures of autonomous and controlled motivation, the theory of planned…
Difficult memory task during postural tasks of various difficulties in young and older people: A pilot study
2007
Abstract Objective This study examined the effects of a difficult and individually tailored additional cognitive task on postural stability and electromyographic (EMG) activities of the ankle dorsi- and plantar-flexors, in young and older individuals performing postural tasks of varying difficulties. Methods Eight young (mean age = 24 years) and eight older (74 years) men took part in the investigation. Centre of pressure velocity and surface EMG of ankle joint muscles were both examined during various postural conditions. Results The main findings suggested that high levels of muscle activity were a characteristic of age-related declines in postural stability. Moreover, during the complex …
Task-induced deactivation in diverse brain systems correlates with interindividual differences in distinct autonomic indices
2018
AbstractNeuroimaging research has shown that different cognitive tasks induce relatively specific activation patterns, as well as less task-specific deactivation patterns. Here we examined whether individual differences in Autonomic Nervous System (ANS) activity during task performance correlate with the magnitude of task-induced deactivation. In an fMRI study, participants performed a continuous mental arithmetic task in a task/rest block design, while undergoing combined fMRI and heart / respiration rate acquisitions using photoplethysmograph and respiration belt. As expected, task performance increased heart-rate and reduced the RMSSD, a cardiac index related to vagal tone. Across partic…
The associations of indoor environment and psychosocial factors on the subjective evaluation of Indoor Air Quality among lower secondary school stude…
2017
Subjective evaluation of Indoor Air Quality (subjective IAQ) reflects both building-related and psychosocial factors, but their associations have rarely been studied other than on the individual level in occupational settings and their interactions have not been assessed. Therefore, we studied whether schools' observed indoor air problems and psychosocial factors are associated with subjective IAQ and their potential interactions. The analysis was performed with a nationwide sample (N = 195 schools/26946 students) using multilevel modeling. Two datasets were merged: (i) survey data from students, including information on schools' psychosocial environment and subjective IAQ, and (ii) data fr…
HBV DNA suppression and HBsAg clearance in HBeAg negative chronic hepatitis B patients on lamivudine therapy for over 5 years
2012
Background & Aims In long-term responder patients, it is unclear whether lamivudine (LAM) monotherapy should be continued or switched to a high-genetic-barrier analogue. This study aims at assessing LAM efficacy over a 5-year period and the residual risk of drug resistance. The rate of HBsAg clearance and LAM long-term safety profile were also evaluated. Methods One hundred and ninety-one patients with chronic HBeAg-negative hepatitis B successfully treated with LAM monotherapy for at least 5years were included. Biochemical and virological tests were assessed every 3months in all patients and HBsAg quantification was performed in 45/191. Reverse-transcriptase (RT) region was directly sequen…