Search results for "ECL"

showing 10 items of 1262 documents

(S)legati (d)al lavoro. Adulti giovani e occupazione tra ricomposizione e frammentazione sociale

2005

Fra i cambiamenti più rilevanti in atto nel mondo del lavoro vi è certamente quello riguardante la diversa accezione che ha assunto l’identità professionale. In presenza di una accentuata volubilità e di una difficile definzione dell’identità professionale – spesso divisa fra molte occupazioni svolte in luoghi e in momenti della propria vita e della giornata diversi – il bisogno di ricomposizione che caratterizza la frammentata società contemporanea e che si declina nei diversi ambiti istituzionali sembra assumere nel lavoro connotazioni assolutamente specifiche che meritano particolare attenzione. Il volume risultato dell’approfondimento di una ricerca condotta in Italia nel 2004 da dieci sedi universitarie e riguardante i percorsi di ricomposizione sociale degli adulti-giovani intende offrire un’analisi dei cambiamenti determinati dal differente modo in cui si declina per questa fascia di età la dimensione lavorativa. Il lavoro ci si è chiesti può essere considerato un ambito di ricomposizione nella frammentata vita degli adulti giovani? Attraverso l’analisi quali-quantitativa di diverso materiale empirico si è inteso scandagliare nel rapporto esistente fra lavoro progetto biografico e formazione dell’identità professionale in un periodo in cui la difficile “transizione alla vita adulta” assume sempre più i caratteri della dilazione continuata e in cui “ricomporre la vita” diventa anche per gli adulti giovani sempre più difficile.
researchProduct

Gaetano Catalano

2011

Francesco Scadutodiritto di libertà religiosalex declaratoriadiritto ecclesiasticolaicitàart.7 Cost.libertà religiosaapostolica legazia di SiciliaGaetano Catalano
researchProduct

El Rey, y por su Magestad, Federico Colonna ... Virey ... de la Ciudad y Reyno de Valencia. Por quanto ... el frances està siempre con las armas en …

1640

Sign.: []1

Francesos Comunitat Valenciana S.XVII Obres anteriors a 1800Reclutament i allistament Comunitat Valenciana S.XVII Obres anteriors a 1800DIG-BH
researchProduct

K-12 game programming course concept using textual programming

2011

Several programming environments have been constructed to facilitate novice programming at K-12 and CS0/CS1 levels. The environments can be roughly divided into those using visual or textual programming. This paper presents a K-12 game programming course concept based on textual programming. The concept is based on an easy-to-use C# library, called Jypeli, built on top of Microsoft XNA Framework. The library tries to maintain advantages of visual programming and avoid challenges of textual programming. In particular, the library helps beginners to program their first games in a short period of time and without a heavy syntactic load. The course concept and an initial evaluation consisting o…

Functional logic programmingComputer sciencecomputer.software_genreExtensible programmingVery high-level programming languageComputingMilieux_COMPUTERSANDEDUCATIONConstraint programmingReactive programmingFifth-generation programming languageProgramming domainProtocol (object-oriented programming)Visual programming languageDeclarative programmingta113Symbolic programmingbusiness.industryProgramming languageInductive programmingConcurrent object-oriented programmingImperative programmingProcedural programmingProgramming paradigmSoftware engineeringbusinessFirst-generation programming languagecomputerFunctional reactive programmingProgramming language theoryProceedings of the 42nd ACM technical symposium on Computer science education
researchProduct

Sobre els priors de la cartoixa d'Aracristi (S.XVI i XVII)

1999

Fundación de monasteriosCenobiosUNESCO::HISTORIA::Historia por épocas::Historia antiguaPrioresDonaciónPatrimonio eclesiástico:HISTORIA::Historia por épocas::Historia antigua [UNESCO]
researchProduct

Drug interactions at GABA(A) receptors.

2002

Neurotransmitter receptor systems have been the focus of intensive pharmacological research for more than 20 years for basic and applied scientific reasons, but only recently has there been a better understanding of their key features. One of these systems includes the type A receptor for the gamma-aminobutyric acid (GABA), which forms an integral anion channel from a pentameric subunit assembly and mediates most of the fast inhibitory neurotransmission in the adult vertebrate central nervous system. Up to now, depending on the definition, 16-19 mammalian subunits have been cloned and localized on different genes. Their assembly into proteins in a poorly defined stoichiometry forms the basi…

GABAA receptorChemistryGeneral NeuroscienceMolecular Sequence DataLoreclezoleNeurotransmissionReceptors GABA-AGABAA-rho receptorGABA AntagonistsNeurotransmitter receptormedicineAnimalsHumansDrug InteractionsAmino Acid SequenceGABA-A Receptor AgonistsGABA-A Receptor AntagonistsBinding siteReceptorGlycine receptorNeuroscienceGABA Agonistsmedicine.drugProgress in neurobiology
researchProduct

Synthesis and Pharmacological Evaluation of [11C]4-Methoxy-N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand S…

2019

The α4/6βδ-containing GABAA receptors are involved in a number of brain diseases. Despite the potential of a δ-selective imaging agent, no PET radioligand is currently available for in vivo imaging...

GABAA receptorStereochemistryGeneral Chemical EngineeringGeneral ChemistryAminobutyric acidImaging agentlcsh:Chemistrychemistry.chemical_compoundlcsh:QD1-999chemistryRadioligandPenetrant (biochemical)BenzamideReceptorPreclinical imagingACS Omega
researchProduct

The architecture of the first garages of Valencia

2014

[ES] El desarrollo y la expansión del automóvil a principios de siglo XX originó la necesidad de lugares de guarda y custodia: los garajes, que, además, servían como talleres, lavaderos, venta de accesorios y gasolina, y, en ocasiones, funcionaron también como agencias de exposición y venta de vehículos. Las construcciones destinadas a garaje se diseñaban con un programa de necesidades bien definido y con una estética acorde a los edificios de tendencias eclécticas, modernistas y post-modernistas de la época. En este trabajo se aborda el nacimiento de estas instalaciones en la ciudad de Valencia, hasta finales de los años veinte, y se muestra la evolución en el emplazamiento, la distribució…

GarajesmodernismArquitectura i societatautomóvilgarajes; modernismo; eclecticismo; Valencia; automóvilGarageseclecticismgarajesmodernismogaragescarCargarages; modernism; eclecticism; Valencia; carEclecticismModernisme (Arquitectura)ModernismeclecticismoValenciaPROYECTOS DE INGENIERIAArquitectura
researchProduct

The diversity of GABAA receptors. Pharmacological and electrophysiological properties of GABAA channel subtypes.

1998

The amino acid gamma-aminobutyric-acid (GABA) prevails in the CNS as an inhibitory neurotransmitter that mediates most of its effects through fast GABA-gated Cl(-)-channels (GABAAR). Molecular biology uncovered the complex subunit architecture of this receptor channel, in which a pentameric assembly derived from five of at least 17 mammalian subunits, grouped in the six classes alpha, beta, gamma, delta, sigma and epsilon, permits a vast number of putative receptor isoforms. The subunit composition of a particular receptor determines the specific effects of allosterical modulators of the GABAARs like benzodiazepines (BZs), barbiturates, steroids, some convulsants, polyvalent cations, and et…

Gene isoformMacromolecular SubstancesProtein ConformationProtein subunitNeuroscience (miscellaneous)LoreclezoleConvulsantsBiologyInhibitory postsynaptic potentialGABAA-rho receptorSubstrate SpecificityGABA AntagonistsCellular and Molecular NeuroscienceBenzodiazepinesMiceChloride ChannelsmedicineAnimalsHumansProtein IsoformsReceptorGABA Agonistsgamma-Aminobutyric AcidAnestheticsMice KnockoutBinding SitesIon TransportGABAA receptorReceptors GABA-ARecombinant ProteinsRatsElectrophysiologyNeurologyBiochemistryBarbituratesSteroidsHeterologous expressionIon Channel Gatingmedicine.drugMolecular neurobiology
researchProduct

Semi-automatic quantitative RT-PCR to measure CYP induction by drugs in human hepatocytes

2003

An assay has been developed for the quantitative measurement of CYP mRNA content of the major human isoforms (1A1, 1A2, 2A6, 2B6, 2C9, 2C19, 2D6, 2E1, 3A4 and 3A5) in human hepatocytes. The method is based on the conversion of mRNAs into their corresponding cDNAs, followed by PCR amplification using appropriate primers. Making use of appropriate internal and external standards it is possible to estimate changes in CYP mRNA content of hepatocytes. The technique has been standardised to run semi-automatically. This procedure can be used to assess the CYP induction potential of new pharmaceuticals at a pre-clinical stage of development. To this aim, human hepatocytes obtained from functional l…

Gene isoformMessenger RNADrug-Related Side Effects and Adverse ReactionsbiologyReverse Transcriptase Polymerase Chain ReactionDrug Evaluation PreclinicalCytochrome P450General MedicineToxicologyIsozymeMolecular biologyReverse transcriptaseXenobioticsReverse transcription polymerase chain reactionReal-time polymerase chain reactionCytochrome P-450 Enzyme SystemBiochemistryEnzyme InductionComplementary DNAHepatocytesbiology.proteinHumansBiological AssayRNA MessengerCells CulturedToxicology in Vitro
researchProduct