Search results for "ECs"

The determinants of subjective economic well-being: an analysis on Italian-Silc data

2011

Using Italian data on Income and living conditions for the year 2005, the paper investigates the main determinants of households’ subjective economic well-being by means of a Partial Proportional Ordered Logit Model. According to a joint subjective and objective perspective of analysis, we use as dependent variable the perceived ability of households to make ends meet. Whereas, we use as explanatory variables some objective aspects of living conditions relating to housing, financial equilibrium, possession of durables and quality of residence place and some socio-demographic characteristics. The empirical results show that the financial strain is the most relevant dimension of living condit…

INTELLECTUAL FILTERS AND THE DISSEMINATION OF SMITHIANISM AN INTRODUCTORY NOTE

2020

Adfam Smith’s thought reached every corner of the world in a short lapse of time but made its entrance through institutional, cultural, linguistic, religious and political filters. These filters are not neutral and affected the reading, understanding and use of Smithian ideas. I chose the keyword ‘intellectual filters’ to denote all of the contextual elements whose influence determines whether and how a foreign paradigm penetrates a country and creates its effects.

Adam Smith Across the World. The spread of his thought and the intellectual filters.

2020

Recensione di Maria Pia Paganelli, Dennis C. Rasmussen and Craig Smith (eds), Adam Smith and Rousseau. Ethics, Politics, Economics, Edinburgh, Edinbu…

2019

The role of punishment in the works of Adam Smith

2009

The reformation of criminal justice is one of the great themes in Enlightenment culture and concerned its main exponents from Montesquieu to Beccaria, Filangieri, Bentham. One of the traits of greater modernity in the theories worked out by juridical Enlightenment is the resort to the utilitarianinspired economic analysis. Adam Smith doesn't back out of this scientific and civil commitment, but his doctrine appears significantly different though contemporary to juridical Enlightenment, and is also based on economic argumentations. In this work we will look through the main writings which contain the Smithian thought in search of those parts dealing with the theme of punishment and its socia…

Model interpretation from the additive elements of the PWRSS in GLMMs

2013

Generalized Linear Mixed models(GLMMs)have rapidly become a widely used tool for modelling clustered and longitudinal data with non-Normal responses. Although a large amount of work has been done in the literature on likelihood-based inference on GLMMs,little seems to have been done on the decomposition of the total variability associated to the different components of a mixed model.In this work we try to generalize the idea of likelihood additive elements Whittaker,1984), proposed in the context of GLMs,to the case of GLMMs by using the Penalized Weighted Residual Sum of Squares(PWRSS). The proposal is illustrated by means of areal application.

Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort

2017

Although evidence for the heterogeneity of asthma accumulated, consensus for definitions of asthma phenotypes is still lacking. Obesity may have heterogeneous effects on various asthma phenotypes. We aimed to distinguish asthma phenotypes by latent class analysis and to investigate their associations with different obesity parameters in adults using a population-based Swiss cohort (SAPALDIA). We applied latent class analysis to 959 self-reported asthmatics using information on disease activity, atopy, and age of onset. Associations with obesity were examined by multinomial logistic regression, after adjustments for age, sex, smoking status, educational level, and study centre. Body mass ind…

Frequent Alteration of the Yin Yang 1/Raf-1 Kinase Inhibitory Protein Ratio in Hepatocellular Carcinoma

2011

The transcription factor Yin Yang 1 (YY1) can favor several aspects of tumorigenesis. In turn, Raf-1 Kinase Inhibitor Protein (RKIP) inhibits the oncogenic activities of MAPK and NF-κB pathways and promotes drug-induced apoptosis. Mutual influences between YY1 and RKIP may exist, and there are already separate evidences that relevant increases in YY1 and reductions in RKIP occur in hepatocellular carcinoma (HCC). However, the levels of the two factors have never been concomitantly examined in HCC. We evaluated by RT-PCR the mRNA levels of YY1, YY1AP, RKIP, and survivin in 35 clinical HCCs (91% HCV-related), in their adjacent cirrhotic tissues and in 6 healthy livers. Immunohistochemical ana…

Peginterferon-Α_2B plus ribavirin is more effective than peginterferon-Α_2A plus ribavirin in menopausal women with chronic hepatitis C.

2012

Under-enrolment of women to randomized clinical trials, including chronic hepatitis C, has long been recognized. The aim of this study was to identify factors predictive of sustained virological response (SVR) to PEG IFN/Ribavirin antiviral therapy in relation to gender and reproductive status of female patients involved. Seven hundred and forty-six treatment-naïve patients (431 men, 315 women) treated with Peg-IFNα-2a (180 μg/week) or Peg-IFNα-2b (1.5 μg/kg/week) plus ribavirin (800–1400 mg/day) for 24 or 48 weeks were studied between 2006 and 2010. Differences in SVR rate, overall and by gender were assessed after adjustment and propensity score matching. SVR was obtained in 44.2% of Peg-…

Modelling the non-linear multiple-lag effects of ambient temperature on mortality in Santiago and Palermo: a constrained segmented distributed lag ap…

2008

Objectives: Exposure to ambient temperature can affect mortality levels for days or weeks following exposure, making modelling such effects in regression analysis of daily time-series data complex. Methods: We propose a new approach involving a multi-lag segmented approximation to account for the non-linear effect of temperature and the use of two different penalised spline bases to model the distributed lag of both heat and cold exposure. Compared with standard splines, the novel penalised framework is more flexible at short lags where change in coefficients is greatest, and selection of the maximum lag appears substantially less important in determining the overall pattern of the effect. …