Search results for "EDUCATION"

showing 10 items of 26766 documents

Cold adaptation drives population genomic divergence in the ecological specialist, Drosophila montana

2020

Funding: UK Natural Environment Research Council (Grant Number(s): NE/L501852/1, NE/P000592/1); Academy of Finland (GrantNumber(s): 267244, 268214, 322980), Ella ja Georg Ehrnroothin Säätiö. Detecting signatures of ecological adaptation in comparative genomics is challenging, but analysing population samples with characterised geographic distributions, such as clinal variation, can help identify genes showing covariation with important ecological variation. Here, we analysed patterns of geographic variation in the cold-adapted species Drosophila montana across phenotypes, genotypes and environmental conditions and tested for signatures of cold adaptation in population genomic divergence. We…

0301 basic medicine0106 biological sciencesCandidate geneEcological selectionQH301 Biology01 natural sciencesGenomeDivergencekylmänkestävyysChill coma recovery timeCCRTD. montanamuuntelu (biologia)sopeutuminen0303 health scienceseducation.field_of_studyGEMontanaEcologyGenomicsgenomiikkageneettinen muunteluCline populationsEnvironmental adaptationpopulaatiogenetiikkaDrosophilaGE Environmental SciencesmahlakärpäsetPopulationQH426 GeneticsBiologyCold tolerance010603 evolutionary biology03 medical and health sciencesQH301GeneticsAnimalseducationQH426Ecology Evolution Behavior and SystematicsCTmin030304 developmental biologyComparative genomicsWhole genome sequencingBayes TheoremDAS030104 developmental biologyGenetics PopulationGenomic divergenceMetagenomicsAdaptation
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The Comparison of Cellulolytic Activity of the Modified Soil Treated with Roundup

2016

Abstract The activity of soil microorganisms affects soil fertility and structure, what leads to satisfactory crop yields, thanks to changes in the decay of organic matter. Their activity may be impaired as a result of application by farmers both fertilizers and pesticides. The degradation of cellulosic biomass represents an important part of the carbon cycle within the biosphere. Cellulolitic microorganisms are responsible for this decomposition, as they produced the enzymes of the cellulase complex. The aim of the study was to compare the cellulolytic activity of soil with Roundup and modified using urea phosphate and / or manure. The pot experiment was conducted under laboratory conditio…

0301 basic medicine03 medical and health sciences030104 developmental biologyEnvironmental EngineeringEcologyChemistryEnvironmental chemistry030106 microbiologyEnvironmental Chemistrycomplex mixturesEducationChemistry-Didactics-Ecology-Metrology
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Zur Bedeutsamkeit von Operationalisierungen medienpädagogischer Grundbegriffe: Kritisch-rationale Anmerkungen zur Medienbildung

2017

Der hier dargestellte Entwurf einer kritisch-rationalen Medienbildung basiert auf dem Entwurf einer kritisch-rationalen Medienpädagogik. Die Medienpädagogik im Allgemeinen und die Medienbildung im Speziellen müssen sich in der Bestimmung ihrer Grundbegriffe auf allgemeinpädagogische Arbeiten rückbeziehen und sollten nicht versuchen, ihre Grundbegriffe komplett neu zu definieren. Dies wird in diesem Beitrag exemplarisch für die Grundbegriffe Erziehung, Sozialisation und Bildung getan. Der Bildungsbegriff wird ausführlicher behandelt und es wird dafür plädiert, zwischen einer Medienausbildung und Medienselbstbildung zu unterscheiden. Beide Aspekte sind gleichermassen relevant für die Medienbi…

0301 basic medicine03 medical and health sciences030104 developmental biologykritischer rationalismusLC8-6691General MedicineSpecial aspects of educationMedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung
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Neither Diplectanum nor specific: a dramatic twist to the taxonomic framework of Diplectanum (Monogenea: Diplectanidae).

2019

The taxonomy of the genus Diplectanum has been exclusively based on morphological features, with 28 nominal species parasitic on perciform fishes recognised. We used molecular data, to our knowledge for the first time, to evaluate the taxonomic framework of Diplectanum, infer the relationships amongst species attributed to this genus, re-assess the degree of host specificity and explore the population genetic structure of Diplectanum spp. parasitising Mediterranean sciaenids, which are potential target fish species for aquaculture diversification in the region. A minimum of 10 specimens of Diplectanum spp. were sequenced per host species (Argyrosomus regius, Sciaena umbra, Umbrina canariens…

0301 basic medicine030231 tropical medicinePopulationZoologyTrematode InfectionsBiologyHost Specificity03 medical and health sciencesMonophylyFish Diseases0302 clinical medicineGenusAnimalsInternal transcribed spacereducationPhylogenyeducation.field_of_studyCytochrome c oxidase subunit IFishesGenetic divergenceType species030104 developmental biologyInfectious DiseasesMolecular phylogeneticsParasitologyTrematodaInternational journal for parasitology
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2016

Near Eastern genomes from Iran The genetic composition of populations in Europe changed during the Neolithic transition from hunting and gathering to farming. To better understand the origin of modern populations, Broushaki et al. sequenced ancient DNA from four individuals from the Zagros region of present-day Iran, representing the early Neolithic Fertile Crescent. These individuals unexpectedly were not ancestral to early European farmers, and their genetic structures did not contribute significantly to those of present-day Europeans. These data indicate that a parallel Neolithic transition probably resulted from structured farming populations across southwest Asia. Science , this issue …

0301 basic medicine2. Zero hungereducation.field_of_studyMultidisciplinaryHuman migrationbusiness.industryEcologyPopulation structurePopulationBiologyGenome03 medical and health sciences030104 developmental biologyAfghanAgriculturebusinesseducationScience
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TReND in Africa: Toward a Truly Global (Neuro)science Community

2020

TReND is a volunteer-scientist run charity dedicated to promoting research and education on the African continent. Focusing on neuroscience, we discuss approaches to address some of the factors that currently stifle Africa's scientific development and our experience in implementing them.

0301 basic medicine2019-20 coronavirus outbreakBiomedical ResearchCapacity BuildingCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Information DisseminationPublic policyPublic PolicyArticleneuroscience03 medical and health sciences0302 clinical medicinePolitical scienceHumanseducationInformation Disseminationbusiness.industryGeneral NeuroscienceNeurosciencesCapacity buildingPublic relationsFacultyComputingMilieux_GENERAL030104 developmental biologyCharitiesScientific developmentAfricabusiness030217 neurology & neurosurgeryNeuron
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Decline in the incidence of colorectal cancer and the associated mortality in young Italian adults

2020

Objective The incidence of colorectal cancer (CRC) declines among subjects aged 50 years and above. An opposite trend appears among younger adults. In Europe, data on CRC incidence among younger adults are lacking. We therefore aimed to analyse European trends in CRC incidence and mortality in subjects younger than 50 years. Design Data on age-related CRC incidence and mortality between 1990 and 2016 were retrieved from national and regional cancer registries. Trends were analysed by Joinpoint regression and expressed as annual percent change. Results We retrieved data on 143.7 million people aged 20–49 years from 20 European countries. Of them, 187 918 (0.13%) were diagnosed with CRC. On a…

0301 basic medicine2312ColonPopulationSocio-culturalecolorectal cancercolorectal cancer screening03 medical and health sciencesYoung Adult0302 clinical medicineEpidemiology of cancerMedicineHumans1506Risk factoreducationeducation.field_of_studycancer epidemiology Colorectal cancer colorectal cancer screeningbusiness.industryIncidence (epidemiology)Mortality ratescreeningIncidenceGastroenterologyCancermedicine.diseaseObesityAnnual Percent ChangeEurope030104 developmental biologyItaly030211 gastroenterology & hepatologyepidemiologybusinessColorectal NeoplasmsDemographycancer epidemiologySEER Program
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Unity Makes Strength: A Review on Mutualistic Symbiosis in Representative Insect Clades

2019

Settled on the foundations laid by zoologists and embryologists more than a century ago, the study of symbiosis between prokaryotes and eukaryotes is an expanding field. In this review, we present several models of insect–bacteria symbioses that allow for the detangling of most known features of this distinctive way of living, using a combination of very diverse screening approaches, including molecular, microscopic, and genomic techniques. With the increasing the amount of endosymbiotic bacteria genomes available, it has been possible to develop evolutionary models explaining the changes undergone by these bacteria in their adaptation to the intracellular host environment. The establishmen…

0301 basic medicine<i>Buchnera</i>Sulcia030106 microbiologyPopulationminimal genomesSymbiotic replacementconsortium<i>Tremblaya</i>Reviewsymbiotic replacementPrimary endosymbiontGenomeGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesMinimal genomesBuchneraSymbiosisgenome-reduction syndromelcsh:ScienceCladeeducationEcology Evolution Behavior and Systematicseducation.field_of_studyendosymbiosisEndosymbiosisEndosymbiosisbiologyHost (biology)secondary endosymbiontPaleontologyprimary endosymbiontTremblayaGenome-reduction syndromebiology.organism_classificationSecondary endosymbiont030104 developmental biology<i>Sulcia</i>Space and Planetary ScienceEvolutionary biologylcsh:QAdaptationBuchneraConsortiumLife
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Consequences of single-locus and tightly linked genomic architectures for evolutionary responses to environmental change

2020

AbstractGenetic and genomic architectures of traits under selection are key factors influencing evolutionary responses. Yet, knowledge of their impacts has been limited by a widespread assumption that most traits are controlled by unlinked polygenic architectures. Recent advances in genome sequencing and eco-evolutionary modelling are unlocking the potential for integrating genomic information into predictions of population responses to environmental change. Using eco-evolutionary simulations, we demonstrate that hypothetical single-locus control of a life history trait produces highly variable and unpredictable harvesting-induced evolution relative to the classically applied multi-locus mo…

0301 basic medicineAcademicSubjects/SCI011400106 biological sciencesLinkage disequilibriumMultifactorial Inheritanceevolutionary simulationEnvironmental changeGenetic LinkageJhered/401 natural sciencesGenetics (clinical)recombination rate0303 health scienceseducation.field_of_studystructural genomic variationInheritance (genetic algorithm)Adaptation PhysiologicalBiological Evolutionclimate changePerspectiveTraitympäristönmuutoksetBiotechnologyPopulationevoluutioEnvironmentBiology010603 evolutionary biologyLife history theory03 medical and health sciencesVDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470GeneticsEvolutionary dynamicseducationMolecular BiologySelection (genetic algorithm)030304 developmental biologygeenitModels GeneticGenetic Driftilmastonmuutoksetgenetic architectureGenetic architectureEditor's Choice030104 developmental biologyEvolutionary biologyperimäGene-Environment InteractionAdaptationlinkage disequilibrium
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Role of AxyZ Transcriptional Regulator in Overproduction of AxyXY-OprZ Multidrug Efflux System in Achromobacter Species Mutants Selected by Tobramycin

2017

ABSTRACT AxyXY-OprZ is an RND-type efflux system that confers innate aminoglycoside resistance to Achromobacter spp. We investigated here a putative TetR family transcriptional regulator encoded by the axyZ gene located upstream of axyXY-oprZ . An in-frame axyZ gene deletion assay led to increased MICs of antibiotic substrates of the efflux system, including aminoglycosides, cefepime, fluoroquinolones, tetracyclines, and erythromycin, indicating that the product of axyZ negatively regulates expression of axyXY-oprZ . Moreover, we identified an amino acid substitution at position 29 of AxyZ (V29G) in a clinical Achromobacter strain that occurred during the course of chronic respiratory tract…

0301 basic medicineAchromobacterCefepime030106 microbiologyPopulationAchromobacterMicrobial Sensitivity TestsBiologymedicine.disease_causeMicrobiology03 medical and health scienceschemistry.chemical_compoundAntibiotic resistanceBacterial ProteinsMechanisms of ResistanceDrug Resistance Multiple BacterialTobramycinmedicineHumansPharmacology (medical)TetRAmino Acid Sequence[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM]educationComputingMilieux_MISCELLANEOUSPharmacologyeducation.field_of_studyPseudomonas aeruginosaMembrane Transport Proteins[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyGene Expression Regulation Bacterialbiology.organism_classification[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyAnti-Bacterial Agents3. Good healthInfectious DiseasesAmino Acid SubstitutionchemistryPseudomonas aeruginosaTobramycinTrans-ActivatorsEffluxGene DeletionBacterial Outer Membrane Proteinsmedicine.drugAntimicrobial Agents and Chemotherapy
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