Search results for "ELF"

showing 10 items of 5893 documents

Self-assembled multivalent (SAMul) ligand systems with enhanced stability in the presence of human serum

2019

Self-assembled cationic micelles are an attractive platform for binding biologically-relevant polyanions such as heparin. This has potential applications in coagulation control, where a synthetic heparin rescue agent could be a useful replacement for protamine, which is in current clinical use. However, micelles can have low stability in human serum and unacceptable toxicity profiles. This paper reports the optimi- sation of self-assembled multivalent (SAMul) arrays of amphiphilic ligands to bind heparin in competitive conditions. Specifically, modification of the hydrophobic unit kinetically stabilises the self-assembled nanostructures, preventing loss of binding ability in the presence of…

02 engineering and technologyheparinLigands01 natural sciencesMicelleGeneral Materials ScienceMicellesnanomaterialsMolecular StructurenanotechnologybiologyChemistrybiomaterialself-assemblyHeparinsimulation021001 nanoscience & nanotechnologyCholesterolhydrolysisThermodynamics0210 nano-technologyHydrophobic and Hydrophilic Interactionsbiomaterialsmedicine.drugBiocompatibilityCell Survivalmicellesexperimental characterizationserum albuminBiomedical EngineeringSerum albuminself-assembly; nanotechnology; biomaterials; simulation; experimental characterization010402 general chemistrySurface-Active Agentsthermodynamicsbiocompatibilitytoxicity testingAmphiphilemedicineHumansMTT assaycoagulationhydrophobicityHeparinLigandligandscholesteroltoxicitybinding capacityProtaminemolecular dynamicsNanostructures0104 chemical sciencesKineticsblood serumbiology.proteinBiophysicshuman cell linesanions
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Barriers and facilitators of older people's mHealth usage: a qualitative review of older people's views

2018

The aim of this qualitative evidence synthesis is to identify and assess existing\ud evidence on barriers to and facilitators of older people’s usage of mHealth. Existing\ud literature identified many factors that affect people’s experiences and perceptions of\ud mHealth, which are in turn influenced by their personal circumstances and biography.\ud The following themes were identified using the thematic synthesis approach: (a)\ud perception of usefulness, (b) user requirements, (c) self-efficacy, (d) sense of self and\ud control, (e) privacy and confidentiality, and (f) cost. MHealth devices and services are\ud complex interventions that have to be integrated into an older person’s life in…

020205 medical informaticsSocial Psychologymedia_common.quotation_subjectApplied psychologyPsychology of self02 engineering and technologyHMhyväksyminenAffect (psychology)User requirements documentPanacea (medicine)older people03 medical and health sciences0302 clinical medicinePromotion (rank)barriers and facilitatorsuser perspectivesRA0421qualitative evidence synthesisPerceptiontechnology acceptance0202 electrical engineering electronic engineering information engineeringConfidentiality030212 general & internal medicinemHealthmedia_commonCommunicationHuman-Computer InteractionmHealthteknologiakäyttäjäkokemusPsychologyikääntyneet
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Soft Innovation Resources: Enabler for reversal in GDP Growth in the Digital Economy

2018

While Finland and Singapore have been maintaining world digital leaders position, they demonstrate interlaced contrast: high welfare with low GDP growth in Finland and higher GDP growth with lower welfare in Singapore. This provokes an uncaptured GDP postulate that Finnish wellbeing has developed more than one might conclude by GDP. However, a recent reversal in the GDP growth trend suggests the possibility that uncaptured GDP contributes to remove structural impediments in GDP growth.This paper demonstrates this hypothesis. An empirical analysis elucidating the inside the national accountings and institutional systems revealed that soft innovation resources have substituted for service cap…

020209 energymedia_common.quotation_subjecttuottavuus02 engineering and technologyIntellectual propertyresurssitdigital economy0502 economics and business0202 electrical engineering electronic engineering information engineeringEconomicsDigital economysoft innovation resourcesFinlandmedia_commonta113Singaporeta51105 social sciencesuusi talousproductivity paradoxInternational economicsstructural impediments in growthinnovaatiotProduct (business)Capital (economics)Service (economics)Productivity paradoxPosition (finance)bruttokansantuoteWelfare050203 business & management
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Comments on “Overflow characteristics of streamlined weirs based on model experimentation” by Bagheri S. and Kabiri-Samani A

2021

Abstract In this paper the stage-discharge equation of a streamlined weir is theoretically deduced applying the Π-Theorem of dimensional analysis and the self-similarity theory. The coefficients of the new stage-discharge relationship are estimated using the experimental results by Bagheri and Kabiri-Samani.

0207 environmental engineering02 engineering and technology01 natural sciencesComputer Science Applications010309 opticsDimensional analysis Discharge coefficient Self-similarity Stage-discharge relationship Streamlined weirPhysics::Plasma PhysicsModeling and Simulation0103 physical sciencesWeirApplied mathematicsSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliElectrical and Electronic Engineering020701 environmental engineeringInstrumentationMathematics
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Towards the Design of Robotic Drivers for Full-Scale Self-Driving Racing Cars

2019

Autonomous vehicles are undergoing a rapid development thanks to advances in perception, planning and control methods and technologies achieved in the last two decades. Moreover, the lowering costs of sensors and computing platforms are attracting industrial entities, empowering the integration and development of innovative solutions for civilian use. Still, the development of autonomous racing cars has been confined mainly to laboratory studies and small to middle scale vehicles. This paper tackles the development of a planning and control framework for an electric full scale autonomous racing car, which is an absolute novelty in the literature, upon which we report our preliminary experim…

0209 industrial biotechnologyAutomotive self-driving car control roboticsbusiness.industryComputer scienceScale (chemistry)Control (management)Automotive industryRobotics02 engineering and technologyTrack (rail transport)Vehicle dynamicsModel predictive control020901 industrial engineering & automationSettore ING-INF/04 - Automatica020204 information systems0202 electrical engineering electronic engineering information engineeringSystems engineeringArtificial intelligencebusiness2019 International Conference on Robotics and Automation (ICRA)
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Machine Learning Approaches for Activity Recognition and/or Activity Prediction in Locomotion Assistive Devices—A Systematic Review

2020

Locomotion assistive devices equipped with a microprocessor can potentially automatically adapt their behavior when the user is transitioning from one locomotion mode to another. Many developments in the field have come from machine learning driven controllers on locomotion assistive devices that recognize/predict the current locomotion mode or the upcoming one. This review synthesizes the machine learning algorithms designed to recognize or to predict a locomotion mode in order to automatically adapt the behavior of a locomotion assistive device. A systematic review was conducted on the Web of Science and MEDLINE databases (as well as in the retrieved papers) to identify articles published…

0209 industrial biotechnologyComputer science0206 medical engineeringWalkingReview02 engineering and technologyMachine learningcomputer.software_genrelcsh:Chemical technologyBiochemistryField (computer science)Analytical ChemistryActivity recognition020901 industrial engineering & automationMode (computer interface)Robustness (computer science)Humansassistive deviceslcsh:TP1-1185Electrical and Electronic EngineeringInstrumentationbusiness.industryembedded sensorsSelf-Help Devices020601 biomedical engineeringAtomic and Molecular Physics and Opticslocomotionmachine learningArtificial intelligencebusinesscomputerAlgorithmsSensors
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A Self-Contained Electro-Hydraulic Cylinder with Passive Load-Holding Capability

2019

Self-contained electro-hydraulic cylinders have the potential to replace both conventional hydraulic systems and the electro-mechanical counterparts enhancing energy efficiency, plug-and-play installation, and reduced maintenance. Current commercial solutions of this technology are limited and typically tailor-made, whereas the research emphasis is primarily on cost efficiency and power applications below five [kW]. Therefore, there is the need of developing more flexible systems adaptable to multiple applications. This research paper offers a contribution in this regard. It presents an electro-hydraulic self-contained single-rod cylinder with passive load-holding capability, sealed tank, c…

0209 industrial biotechnologyControl and OptimizationComputer science020209 energyEnergy Engineering and Power TechnologyComputerApplications_COMPUTERSINOTHERSYSTEMS02 engineering and technologySelf-contained cylinderslcsh:TechnologyAutomotive engineeringCylinder (engine)law.invention020901 industrial engineering & automationlawload-holding valves0202 electrical engineering electronic engineering information engineeringCylinderElectrical and Electronic EngineeringHydraulic machineryEngineering (miscellaneous)Renewable Energy Sustainability and the EnvironmentOscillationlcsh:TmodelingSelf-contained cylinders; electro-hydraulic systems; load-holding valves; modelingPower (physics)VDP::Teknologi: 500ActuatorEnergy (signal processing)electro-hydraulic systemsEnergy (miscellaneous)
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A Comparison Study of a Novel Self-Contained Electro-Hydraulic Cylinder versus a Conventional Valve-Controlled Actuator—Part 2: Energy Efficiency

2019

This research paper presents the second part of a comparative analysis of a novel self-contained electro-hydraulic cylinder with passive load-holding capability against a state of the art, valve-controlled hydraulic system that is typically used in load-carrying applications. After addressing the control design and motion performance in the first part of the study, the comparison is now focused on the systems&rsquo

0209 industrial biotechnologyControl and OptimizationComputer scienceHydraulicspassive load-holdingenergy recoveryComputerApplications_COMPUTERSINOTHERSYSTEMS02 engineering and technologyAutomotive engineeringlaw.invention020901 industrial engineering & automationlinear actuatorslawload-carrying applications0202 electrical engineering electronic engineering information engineeringHydraulic machineryenergy efficiencyEnergy recoveryVDP::Teknologi: 500::Materialteknologi: 520020208 electrical & electronic engineeringEnergy consumptionLinear actuatorFluid powerControl and Systems Engineeringproportional directional control valvesActuatorself-contained cylinderselectro-hydraulic systemsEfficient energy useActuators
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A Comparison Study of a Novel Self-Contained Electro-Hydraulic Cylinder versus a Conventional Valve-Controlled Actuator—Part 1: Motion Control

2019

This research paper presents the first part of a comparative analysis of a novel self-contained electro-hydraulic cylinder with passive load-holding capability against a state of the art, valve-controlled actuation system that is typically used in load-carrying applications. The study is carried out on a single-boom crane with focus on the control design and motion performance analysis. First, a model-based design approach is carried out to derive the control parameters for both actuation systems using experimentally validated models. The linear analysis shows that the new drive system has higher gain margin, allowing a considerably more aggressive closed-loop position controller. Several b…

0209 industrial biotechnologyControl and OptimizationSettling timeComputer sciencepassive load-holding020209 energy02 engineering and technologyactive damping020901 industrial engineering & automationlinear actuatorsmodeling and simulationControl theoryPosition (vector)load-carrying applications0202 electrical engineering electronic engineering information engineeringOvershoot (signal)feedback control systemsLinear actuatorMotion controlControl and Systems EngineeringRise timeproportional directional control valvesActuatorself-contained cylinderselectro-hydraulic systemslinear control designActuators
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Professional stakeholders' views of the use of digital technologies in Spanish long-term care

2018

Demographic change in Europe has resulted in an aging population, which presents new challenges for implementing and managing long-term care (LTC) systems. One solution aims to increase the efficiency of LTC by using digital technologies. This article focuses on professionals’ opinions of the use of digital technologies in the administration of Spain’s long-term care law (Law 39/2006, December 14, LAPAD). This qualitative research is part of SoCaTel, an H2020 project on the co-creation of LTC services in Europe. Ten focus groups were held with health professionals, care-taking relatives, and care workers, and six semistructured in-depth interviews were conducted with care recipients in Cata…

0209 industrial biotechnologySocial PsychologySocial Welfare02 engineering and technologydigitalizationLAPADsocial services020901 industrial engineering & automation0502 economics and businessdigital technologieslcsh:T58.5-58.64lcsh:Information technologybusiness.industryCommunication05 social sciencesPublic relationsHuman-Computer InteractionLong-term careSpainInformation and Communications TechnologyICTLTClong-term careBusiness050203 business & managementHuman Technology
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