Search results for "ELIC"

showing 10 items of 1282 documents

Synthesis and structural properties of hexaaza[5]helicene containing two [1,2,3]triazolo[1,5-a]pyridine moieties

2013

Abstract We have synthesized a novel hexaaza[5]helicene in a straightforward way from neocuproine. The crystal structure has been elucidated with direct-space strategy TALP which demonstrates the power of the powder X-ray diffraction technique. In this crystal structure it is possible to see an interplanar angle of 33(1)° between the two triazolopyridine rings. The centrosymmetric crystal structure is a racemic mixture, but the resolution was not possible due to a ring-chain isomerization in a solution that produces a dynamic racemization.

010405 organic chemistryStereochemistry[CHIM.ORGA]Chemical Sciences/Organic chemistryOrganic ChemistryCrystal structure010402 general chemistry01 natural sciencesBiochemistry0104 chemical sciencesNeocuproinechemistry.chemical_compoundCrystallographychemistryHeliceneDrug DiscoveryPyridineRacemic mixtureTriazolopyridineRacemizationIsomerization
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Description de Artareites landii nov. (Ammonoidea) du Barrémien supérieur de Majastre (sud-est de la France) et discussion sur les Helicancylidae Hya…

2009

25 pages; Dans le secteur de Majastre (Alpes-de-Haute-Provence, SE de la France), le domaine hémipélagique du Crétacé inférieur est exposé à la faveur du décrochement du Poil. Cette position paléogéographique et paléotectonique a permis la récolte d'une faune d'ammonites diversifiée dans le niveau à « petits Barremites ». Il est précisément daté ici pour la première fois et se place entre la base de la sous-zone à Barremense et la base du biohorizon à Breistrofferi de la biozone à Vandenheckei (base du Barrémien supérieur). Au sein de cette faune, Artareites landii nov. sp. est considéré ici, par ses caractéristiques et sa position stratigraphique, comme issu du genre Dissimilites Sarkar. L…

010506 paleontologymedia_common.quotation_subjectPaleontologyArt010502 geochemistry & geophysics01 natural sciencesArtareites nov. genSud-Est de la FranceAmmonoideaHelicancylidaeMonoditidae nov. famMonoditidae nov. fam.Artareites nov. gen.[SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/PaleontologyHumanities0105 earth and related environmental sciencesmedia_common[ SDU.STU.PG ] Sciences of the Universe [physics]/Earth Sciences/PaleontologyBarrémien supérieurCrétacé inférieur
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Characterization of the resistance to Vip3Aa in Helicoverpa armigera from Australia and the role of midgut processing and receptor binding.

2016

AbstractCrops expressing genes from Bacillus thuringiensis (Bt crops) are among the most successful technologies developed for the control of pests but the evolution of resistance to them remains a challenge. Insect resistant cotton and maize expressing the Bt Vip3Aa protein were recently commercialized, though not yet in Australia. We found that, although relatively high, the frequency of alleles for resistance to Vip3Aa in field populations of H. armigera in Australia did not increase over the past four seasons until 2014/15. Three new isofemale lines were determined to be allelic with previously isolated lines, suggesting that they belong to one common gene and this mechanism is relative…

0106 biological sciences0301 basic medicineCrops AgriculturalInsecticidesHelicoverpa armigeraPlant disease resistanceMothsmedicine.disease_cause01 natural sciencesArticleMicrobiology03 medical and health sciencesBacterial ProteinsBacillus thuringiensisBotanymedicineAnimalsBinding siteGeneAllelesDisease ResistancePlant DiseasesMultidisciplinarybiologyToxinfungiAustraliaMidgutbiology.organism_classificationPlants Genetically Modified010602 entomology030104 developmental biologyCry1AcScientific reports
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Very high MHC Class IIB diversity without spatial differentiation in the mediterranean population of greater Flamingos.

2017

WOS: 000397335400001

0106 biological sciences0301 basic medicineGene FlowGenotypeLocal adaptationPopulationGenes MHC Class II010603 evolutionary biology01 natural sciencesIntraspecific competitionGene flowMHC GenesBirds03 medical and health sciences[ SDV.EE.IEO ] Life Sciences [q-bio]/Ecology environment/SymbiosisAnimals[ SDV.IMM ] Life Sciences [q-bio]/Immunology14. Life underwaterSelection GeneticeducationEcology Evolution Behavior and SystematicsAllelic diversity ; Local adaptation ; MHC genes ; Pathogen-mediated balancing selection ; Greater flamingosAllelesLocal adaptationeducation.field_of_studyGenetic diversitybiologyHistocompatibility Antigens Class IIGenetic VariationAllelic diversityMHC genesExonsbiology.organism_classificationPathogen-mediated balancing selection030104 developmental biologyEvolutionary biologyGreater flamingosBiological dispersal[SDV.IMM]Life Sciences [q-bio]/ImmunologyGreater flamingoAdaptation[SDV.EE.IEO]Life Sciences [q-bio]/Ecology environment/SymbiosisResearch Article
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Isolating, characterising and identifying a Cry1Ac resistance mutation in field populations of Helicoverpa punctigera

2018

AbstractTransgenic cotton expressing insecticidal proteins from Bacillus thuringiensis (Bt) has been grown in Australia for over 20 years and resistance remains the biggest threat. The native moth, Helicoverpa punctigera is a significant pest of cotton. A genotype causing resistance to Cry1Ac in H. punctigera was isolated from the field and a homozygous line established. The phenotype is recessive and homozygous individuals possess 113 fold resistance to Cry1Ac. Individuals that carry Cry1Ac resistance genes are rare in Australia with a frequency of 0.033 being detected in field populations. RNAseq, RT-PCR and DNA sequencing reveals a single nucleotide polymorphism at a splice site in the c…

0106 biological sciences0301 basic medicineHelicoverpa punctigeralcsh:MedicinePolymorphism Single Nucleotide01 natural sciencesArticleInsecticide ResistanceHemolysin Proteins03 medical and health sciencesBacterial ProteinsBacillus thuringiensisGenotypeAnimalsPest Control Biologicallcsh:ScienceGeneGeneticsGossypiumMultidisciplinaryBacillus thuringiensis ToxinsbiologyCadherinlcsh:RfungiAustraliaIntronCadherinsResistance mutationbiology.organism_classificationEndotoxinsLepidoptera010602 entomology030104 developmental biologyCry1Aclcsh:QScientific Reports
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The chaperone-like protein Cdc48 regulates ubiquitin-proteasome system in plants.

2021

The degradation of misfolded proteins is mainly mediated by the ubiquitin-proteasome system (UPS). UPS can be assisted by the protein Cdc48 but the relationship between UPS and Cdc48 in plants has been poorly investigated. Here, we analyzed the regulation of UPS by Cdc48 in tobacco thanks to two independent cell lines overexpressing Cdc48 constitutively and plant leaves overexpressing Cdc48 transiently. In the cell lines, the accumulation of ubiquitinated proteins was affected both quantitatively and qualitatively and the amount of proteasomal subunits was modified, while proteolytic activities were unchanged. Similarly, the over-expression of Cdc48 in planta impacted the accumulation of ub…

0106 biological sciences0301 basic medicineHypersensitive responseProgrammed cell deathProteasome Endopeptidase ComplexPhysiologyProtein subunitubiquitinomePlant Science01 natural sciencescryptogeinCdc48Fungal Proteins03 medical and health sciences[CHIM.ANAL]Chemical Sciences/Analytical chemistryValosin Containing ProteinTobacco[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyPlant ImmunityPlant ProteinsbiologyChemistryUbiquitinUbiquitin homeostasisPlants Genetically ModifiedUbiquitinated ProteinsElicitorCell biology030104 developmental biologyproteasomeProteasomeCell cultureChaperone (protein)biology.protein010606 plant biology & botanyPlant, cellenvironmentREFERENCES
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The Odorant-Binding Proteins of the Spider Mite Tetranychus urticae

2021

Spider mites are one of the major agricultural pests, feeding on a large variety of plants. As a contribution to understanding chemical communication in these arthropods, we have characterized a recently discovered class of odorant-binding proteins (OBPs) in Tetranychus urticae. As in other species of Chelicerata, the four OBPs of T. urticae contain six conserved cysteines paired in a pattern (C1–C6, C2–C3, C4–C5) differing from that of insect counterparts (C1–C3, C2–C5, C4–C6). Proteomic analysis uncovered a second family of OBPs, including twelve members that are likely to be unique to T. urticae. A three-dimensional model of TurtOBP1, built on the recent X-ray structure of Varroa destruc…

0106 biological sciences0301 basic medicineModels MolecularProteomicsProteomeOdorant bindingProtein ConformationInsectLigandsReceptors Odorant01 natural scienceschemistry.chemical_compoundTetranychus urticaeBiology (General)SpectroscopyPhylogenymedia_commonmass spectrometryGeneticsbiologyligand-bindingMolecular Structurespider mitesGeneral MedicineTetranychus urticaeComputer Science ApplicationsChemistryConiferyl aldehydedisulfide bridgesTetranychidaeProtein Bindingspider mites.QH301-705.5media_common.quotation_subjectodorant-binding proteinsCatalysisArticleInorganic Chemistry03 medical and health sciencesSpider mite<i>Tetranychus urticae</i>AnimalsAmino Acid SequencePhysical and Theoretical ChemistryQD1-999Molecular BiologySpiderOrganic Chemistrybiology.organism_classification010602 entomology030104 developmental biologychemistryVarroa destructorOdorantsChelicerataInternational Journal of Molecular Sciences
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Multifactorial and Species-Specific Feedback Regulation of the RNA Surveillance Pathway Nonsense-Mediated Decay in Plants

2018

Abstract Nonsense-mediated decay (NMD) is an RNA surveillance mechanism that detects aberrant transcript features and triggers degradation of erroneous as well as physiological RNAs. Originally considered to be constitutive, NMD is now recognized to be tightly controlled in response to inherent signals and diverse stresses. To gain a better understanding of NMD regulation and its functional implications, we systematically examined feedback control of the central NMD components in two dicot and one monocot species. On the basis of the analysis of transcript features, turnover rates and steady-state levels, up-frameshift (UPF) 1, UPF3 and suppressor of morphological defects on genitalia (SMG)…

0106 biological sciences0301 basic medicinePhysiologyRNA StabilityNonsense-mediated decayArabidopsisPlant ScienceBiology01 natural scienceslaw.inventionDephosphorylation03 medical and health sciencesSpecies SpecificityGene Expression Regulation PlantlawArabidopsis thalianaFeedback PhysiologicalRegulation of gene expressionArabidopsis ProteinsMechanism (biology)RNACell BiologyGeneral MedicineRNA surveillancebiology.organism_classificationNonsense Mediated mRNA DecayCell biology030104 developmental biologyRNA PlantSuppressorCarrier ProteinsRNA Helicases010606 plant biology & botanyPlant and Cell Physiology
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Functional characterization of the chaperon-like protein Cdc48 in cryptogein-induced immune response in tobacco

2017

SPEIPMUBINRASUPDATDOCT; Cdc48, a molecular chaperone conserved in different kingdoms, is a member of the AAA+ family contributing to numerous processes in mammals including proteins quality control and degradation, vesicular trafficking, autophagy and immunity. The functions of Cdc48 plant orthologues are less understood. We previously reported that Cdc48 is regulated by S-nitrosylation in tobacco cells undergoing an immune response triggered by cryptogein, an elicitin produced by the oomycete Phytophthora cryptogea. Here, we inv estigated the function of NtCdc48 in cryptogein signalling and induced hypersensitive-like cell death. NtCdc48 was found to accumulate in elicited cells at both th…

0106 biological sciences0301 basic medicineProgrammed cell deathPhysiologyImmunoprecipitationNitrosation[SDV]Life Sciences [q-bio]PopulationPlant ScienceBiologyBioinformatics01 natural sciencesdefence responsescryptogeinFungal Proteins03 medical and health sciencesImmune systemGene Expression Regulation PlantValosin Containing ProteinPlant CellsTobaccoRNA MessengereducationPlant ProteinsRegulation of gene expressioneducation.field_of_studyFungal protein[ SDV ] Life Sciences [q-bio]AutophagyElicitinCell biology030104 developmental biologycell deathChromatography GelCdc48 partnersNtCdc48Protein Binding010606 plant biology & botany
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Hemocyanin genes as indicators of habitat shifts in Panpulmonata?

2018

Hemocyanin is the primary respiratory protein for the majority of the Mollusca and therefore directly interfaces with the physiological requirements of each species and the environments to which they are adapted. Hemocyanin is therefore likely to have been evolutionarily imprinted by significant habitat shifts. In the gastropod clade Panpulmonata (>30,000 species) major realm transitions have occurred multiple times independently and may have contributed to the diversification of this group. Yet, little is known about the adaptive changes linked to these habitat shifts. In order to gain deeper insight into the evolution of panpulmonate hemocyanins and to infer possible impacts associated wi…

0106 biological sciences0301 basic medicinemedicine.medical_treatmentGastropodaStylommatophorachemical and pharmacologic phenomenaLymnaea stagnalis010603 evolutionary biology01 natural sciencesLymnaeidae03 medical and health sciencesHelicidaeSpecies SpecificityGeneticsmedicineAnimalsProtein Isoforms14. Life underwaterMolecular BiologyEcology Evolution Behavior and SystematicsEcosystemPhylogenyGenomebiologyHemocyaninbiology.organism_classificationRespiratory proteinHygrophila (gastropod)030104 developmental biologyEvolutionary biologyPanpulmonataHemocyaninsMolecular phylogenetics and evolution
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