6533b871fe1ef96bd12d1aad
RESEARCH PRODUCT
Synthesis and structural properties of hexaaza[5]helicene containing two [1,2,3]triazolo[1,5-a]pyridine moieties
Oriol VallcorbaBelén AbarcaJordi RiusRafael BallesterosFrançoise ColobertJosé María AmigóFrédéric R. LerouxRafael Ballesteros-garridoRosa Adamsubject
010405 organic chemistryStereochemistry[CHIM.ORGA]Chemical Sciences/Organic chemistryOrganic ChemistryCrystal structure010402 general chemistry01 natural sciencesBiochemistry0104 chemical sciencesNeocuproinechemistry.chemical_compoundCrystallographychemistryHeliceneDrug DiscoveryPyridineRacemic mixtureTriazolopyridineRacemizationIsomerizationdescription
Abstract We have synthesized a novel hexaaza[5]helicene in a straightforward way from neocuproine. The crystal structure has been elucidated with direct-space strategy TALP which demonstrates the power of the powder X-ray diffraction technique. In this crystal structure it is possible to see an interplanar angle of 33(1)° between the two triazolopyridine rings. The centrosymmetric crystal structure is a racemic mixture, but the resolution was not possible due to a ring-chain isomerization in a solution that produces a dynamic racemization.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-08-01 |