Search results for "ELT"
showing 10 items of 2198 documents
Lehtiuutisesta mielikuvaksi, sanoiksi ja säveliksi : Marja Mattlarin "Kehtolaulun" lauluntekoprosessi
2012
Tässä tutkimuksessa käsitellään Marja Mattlarin ”Kehtolaulun” sävellys- ja sanoitusprosessia. Huomion kohteena ovat sanoittamisen ja säveltämisen prosessien välinen vuorovaikutus sekä musiikin ja kirjoitetun kielen välinen kommunikaatio. ”Kehtolaulun” lauluntekoprosessissa sävellys ja sanoitus syntyivät yhtä aikaa ja yhdeltä istumalta. Sen vuoksi pohditaan myös syitä, jotka selittävät kahden simultaanisen prosessin onnistumisen. Tietoa hankitaan teemahaastattelun menetelmällä. Haastateltavana on lauluntekijä Marja Mattlar. Taustateorioina käytetään säveltämisen ja kirjoittamisen prosessikuvauksia. Niiden ja haastatteluaineiston pohjalta hahmotellaan teoriaohjaavan sisällönanalyysin menetelm…
Zur Umsetzung deutscher Lyrik in finnische Musik : am Beispiel Rainer Maria Rilke und Einojuhani Rautavaara
2005
Kaisu Nikula selvitti väitöstutkimuksessaan saksalaisen runouden asemaa suomalaisessa laulumusiikissa.- Taiteellisina merkitysjärjestelminä runokieli ja musiikki ovat lähellä toisiaan, Nikula kuvaa.Nikula pohti muun muassa säveltäjien tekemää runoilijoiden ja runojen valintaa sekä valintaperusteita. - 1800-luvun säveltäjät valitsivat enimmäkseen runoilijoita, jotka esiintyvät samanaikaisesti saksalaisessa lied-perinteessä. Myös runojen kääntäminen molemmille kotimaisille kielille on vaikuttanut laulutekstin valintaan, Nikula huomasi.Esille nousi myös säveltäjien henkilökohtaisia valintaperusteita. 1900-luvun jälkipuoliskolla nousee selkeästi esiin säveltäjien oma runouden tuntemus. Säveltäj…
A GAMING APPROACH FOR CULTURAL HERITAGE KNOWLEDGE AND DISSEMINATION
2019
Abstract. In these last years, video games have become one of the most popular entertainment for children/teenagers/adults thanks to their appealing and seductive features and, in this context, the Serious Games (SG) have become an important research field. The most popular SGs in Cultural Heritage (CH) used the historical building like scenario where the game is playing. In this paper we show the procedure to achieve a CH video game where the Cultural Heritage is the main actor and not the scenario of the game. Furthermore, the game is not a SG but an Action-Adventure Game (AAG) or Survival Game (SuG), in a largest heading it can be classified as Entertainment Games (EGs). The novelty of t…
Documenting the light sensitivity of Spanish Levantine rock art paintings
2015
[EN] A case study to evaluate the use of microfading spectrometry (MFS) for the study of colored systems found in prehistoric rock art paintings was conducted in the Cova Remígia rock-shelter, Castellón (Spain). This rock shelter is part of the rock art sites of the Mediterranean basin on the Iberian Peninsula included in UNESCO s World Heritage List. Some of the paintings belonging to this group are exposed to environmental factors including natural daylight, wind and rain, depending on the time of the day and the season of the year. Therefore, their preservation is a major concern to stakeholders and researchers responsible for protecting and studying these prehistoric paintings. The expe…
A classical phenotype of Anderson-Fabry disease in a female patient with intronic mutations of the GLA gene: a case report
2012
Abstract Background Fabry disease (FD) is a hereditary metabolic disorder caused by the partial or total inactivation of a lysosomal hydrolase, the enzyme α-galactosidase A (GLA). This inactivation is responsible for the storage of undegraded glycosphingolipids in the lysosomes with subsequent cellular and microvascular dysfunction. The incidence of disease is estimated at 1:40,000 in the general population, although neonatal screening initiatives have found an unexpectedly high prevalence of genetic alterations, up to 1:3,100, in newborns in Italy, and have identified a surprisingly high frequency of newborn males with genetic alterations (about 1:1,500) in Taiwan. Case presentation We des…
Looking for determinants of willingness-to-pay for Sibelius Hall, Lahti
2017
The aim of this paper is to determine the factors affecting the willingness-to-pay for a local concert hall, namely Sibelius Hall in Lahti. Our study argues that a high income, the use of cultural services and a positive attitude towards culture were connected to a high willingness-to-pay for Sibelius Hall. Our study revealed that “I do not know” answers can be partly explained by the character of cultural preferences being an acquired taste. As a consequence, the users and respondents exhibiting a positive attitude towards culture may choose the “I do not know” option instead of making a zero bid. peerReviewed
Editorial: Understanding Gamma Delta T Cell Multifunctionality - Towards Immunotherapeutic Applications.
2020
Introduction: gd T cells have been characterized by the expression of a gd T cell receptor (TCR).When the gd TCR and the corresponding ab TCR were first discovered it was assumed that the corresponding cell types were likely to be functionally very similar. However, some 30 years later, we have realized that they are not. Unlike ab T cells, gd T cells (i) sense target antigens independent of MHC molecules; (ii) display NK-cell like innate reactivities, including killing of infected cells as well as microbes; (iii) are able to take up large particulates, including bacteria, and (iv) can act as professional antigen presenting cells. The “stress sensing” abilities of gd T cells have led to a g…
IL-12 Expands and Differentiates Human Vγ2Vδ2 T Effector Cells Producing Antimicrobial Cytokines and Inhibiting Intracellular Mycobacterial Growth
2019
While IL-12 plays a key role in differentiation of protective CD4+ Th1 response, little is known about mechanisms whereby IL-12 differentiates other T-cell populations. Published studies suggest that predominant Vγ2Vδ2 T cells in humans/nonhuman primates (NHP) are a fast-acting T-cell subset, with capacities to rapidly expand and produce Th1 and cytotoxic cytokines in response to phosphoantigen (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP) produced by Mycobacterium tuberculosis (Mtb) or others. However, whether IL-12 signaling pathway mediates fast-acting and Th1 or anti-microbial features of Vγ2Vδ2 T cells remains poorly defined. Here, we show that IL-12, but not other IL-12 fami…
Tumor-Infiltrating γδ T Lymphocytes: Pathogenic Role, Clinical Significance, and Differential Programing in the Tumor Microenvironment.
2014
There is increasing clinical evidence indicating that the immune system may either promote or inhibit tumor progression. Several studies have demonstrated that tumors undergoing remission are largely infiltrated by T lymphocytes [tumor-infiltrating lymphocytes (TILs)], but on the other hand, several studies have shown that tumors may be infiltrated by TILs endowed with suppressive features, suggesting that TILs are rather associated with tumor progression and unfavorable prognosis. γδ T lymphocytes are an important component of TILs that may contribute to tumor immunosurveillance, as also suggested by promising reports from several small phase-I clinical trials. Typically, γδ T lymphocytes …
γδ T Cells Cross-Link Innate and Adaptive Immunity in Mycobacterium tuberculosis Infection
2011
Protective immunity against mycobacterial infections such asMycobacterium tuberculosisis mediated by interactions between specific T cells and activated antigen presenting cells. To date, many aspects of mycobacterial immunity have shown that innate cells could be the key elements that substantially may influence the subsequent adaptive host response. During the early phases of infection, innate lymphocyte subsets play a pivotal role in this context. Here we summarize the findings of recent investigations onγδT lymphocytes and their role in tuberculosis immunity.