Search results for "EMBER"

High Reynolds number Navier-Stokes solutions and boundary layer separation induced by a rectilinear vortex

2013

Abstract We compute the solutions of Prandtl’s and Navier–Stokes equations for the two dimensional flow induced by a rectilinear vortex interacting with a boundary in the half plane. For this initial datum Prandtl’s equation develops, in a finite time, a separation singularity. We investigate the different stages of unsteady separation for Navier–Stokes solution at different Reynolds numbers Re = 103–105, and we show the presence of a large-scale interaction between the viscous boundary layer and the inviscid outer flow. We also see a subsequent stage, characterized by the presence of a small-scale interaction, which is visible only for moderate-high Re numbers Re = 104–105. We also investi…

Architettura in alzato. Questioni di territorio, paesaggio, ambiente

2021

Negata alla tipologia l’architettura del Sud nel saggio riconosce una specifica identità e perfetta eccezionalità nell’essenza del luogo. Se la facciata istituisce un rapporto con l’estetica del paesaggio, i temi che essa sottende definiscono altre significative relazioni. L’ordinamento logico delle membrature, la chiarezza geometrica e il rigore dei rapporti rimandano ad una architettura che si misura, ed è misura stessa, del territorio e della sua morfologia. A sua volta, lo spessore della facciata esprime la relazione con l’ambiente e interpreta in maniera poetica i condizionamenti climatici, intervenendo sul controllo della luce, sui vuoti nei paramenti murari, sulla determinazione dell…

Induction of Human P-Glycoprotein in Caco-2 cells: Development of a Highly Sensitive Assay System for P-Glycoprotein-Mediated Drug Transport

2006

The aim of this work is to develop a highly sensitive assay system for P-gp-mediated transport by using two methods, induction of P-gp and short-term culture of Caco-2 cells. To induce P-gp in Caco-2 cells, cells were cultured in vinblastine-containing medium. The mRNA level of P-gp was approximately 7-fold higher in Caco-2 cells cultured with vinblastine (P-gp-induced Caco-2 cells) than in control cells. Western blot analysis showed a significant increase in P-gp expression. After cell differentiation, the mRNA level of P-gp was downregulated, however, P-gp-induced Caco-2 cells still possessed a 5.6-fold higher mRNA level of P-gp compared to control cells. Polarized transport of substrate …

Britu diplomātija 2. Pasaules kara priekšvakarā un sākumā (1938-1941): izmaiņas politiskajā retorikā

2020

Pētījumā tika analizētas Lielbritānijas diplomātiskā resora pārstāvju runas, paziņojumi un fiksētās liecības no divu metodoloģisko konceptu pozīcijām – miera un kara retorikām - laika posmā no 1938. gada 12. marta (Austrijas aneksijas) līdz 1941. gada 22. jūnijam (PSRS kara pieteikums Vācijai). Lielbritānija Otrā Pasaules kara priekšvakarā un sākumā nebija gatava karam un vēlējās darīt visu iespējamo diplomātiski, kas bija iespējams, lai to novērstu. Saskaroties ar dažādiem apstākļiem, Lielbritānija kļuva par Eiropā vadošo demokrātiju un miera aizstāvi gan pirms, gan arī kara laikā. Premjerministru un viņu Kabinetu vērstās retorikas izmaiņas bija iespējams konstatēt hronoloģiskā veidā un ab…

Il Consiglio europeo e la crisi del debito sovrano

2013

Il lavoro si occupa del ruolo svolto dal Consiglio europeo nel coordinamento delle politiche economiche degli Stati membri dell'UE di fronte alla crisi del debito sovrano, occupandosi in particolare di due problemi: da un lato quello della natura giuridica del Consiglio europeo e, da un altro lato, quello dei riflessi prodotti dall'intervento di quest'ultimo sul modo di funzionamento della cooperazione economica tra gli Stati membri dell'Unione.

Split-ticket voting in German Federal elections, 1953–90: an example of sophisticated balloting?

1999

Abstract Though the German electoral system has provided the opportunity of split-ticket voting since 1953, until now there has only been mere speculation concerning the rationality of ticket-splitting. In this paper we examine the rationality thesis empirically, using data provided by the official representative electoral statistics of the Federal Republic. Modifying the Downsian notion of rational voting, rational ticket-splitting is defined in terms of coalition building and of voters' expectations of the electoral success of candidates and parties. Applying this conceptual framework, it will be shown that the combinations of first and second votes actually chosen by a majority of the Ge…

Négligence illicite et responsabilités multiples: partage ou cumul de responsabilités?

2018

This paper addresses the issue of the distribution of international responsibility between two or more States or between an international organization and its member States in case of violation of obligations of due diligence.

The fundamental Human Rights as European Law Principles: their development through the ECHR principles and the Constitutional traditions conmmon to t…

2011

The need to reinforce the fundamental human rights of EU citizens and of people living in the European Union became a key goal linked to the need to create a European area of freedom, security and justice, one European Union's internal borders were gradually abolished. Respecting fundamental rights while ensuring security and justice in the European Union became two intrinsically linked tasks of European integration in the years to come. Actually two sides of the same coin. Look, for example, the immigration policy. The latest developments have even led to the creation of a Fundamental Rights Agency.

Deep neural networks leveraging different arrangements of molecular fingerprints to define a novel embedding for virtual screening procedure

2022

Negocjacje w Unii Europejskiej na tle negocjacji międzynarodowych

2019

Celem niniejszego artykułu jest wskazanie zasadniczych cech negocjacji w UE na tle klasycznych negocjacji międzynarodowych. Pomimo założenia, że nie należy stawiać znaku równości między negocjacjami unijnymi a międzynarodowymi, to ich komparatystyka jest jak najbardziej uzasadniona, nie tylko z racji międzynarodowego charakteru integracji europejskiej, ale dlatego, że pozwala ona uchwycić wiele istotnych cech, właściwości i atrybutów negocjacji europejskich, które wynikają z natury UE, zwłaszcza w kontekście bezprecedensowej w historii stosunków międzynarodowych instytucjonalizacji procesów integracji. Artykuł składa się z dwóch części, dotyczących odpowiednio negocjacji międzynarodowych i …