Search results for "EOs"
showing 10 items of 2714 documents
Antígenos histo-sanguíneos e infección por rotavirus
2019
La infección por rotavirus es la principal causa de gastroenteritis aguda en niños menores de 5 años en todo el mundo. Su incidencia es similar en países desarrollados y en vías de desarrollo, aunque la mayor mortalidad ocurre en estos últimos. Las vacunas frente a rotavirus han demostrado una gran efectividad en los países industrializados, pero su protección es menor en los países del África subsahariana y Asia. Se ha descrito que los antígenos histo-sanguíneos, presentes en la membrana de los enterocitos, actúan como ligandos para distintos genotipos de rotavirus. Esto podría explicar las diferencias que se observan en su distribución geográfica y la distinta eficacia vacunal de unas áre…
Spatial data fusion and analysis for soil characterization: a case study in a coastal basin of south-western Sicily (southern Italy)
2012
Salinization is one of the most serious problems confronting sustainable agriculture in semi-arid and arid regions. Accurate mapping of soil salinization and the associated risk represent a fundamental step in planning agricultural and remediation activities. Geostatistical analysis is very useful for soil quality assessment because it makes it possible to determine the spatial relationships between selected variables and to produce synthetic maps of spatial variation. The main objective of this paper was to map the soil salinization risk in the Delia-Nivolelli alluvial basin (south-western Sicily, southern Italy), using multivariate geostatistical techniques and a set of topographical, phy…
Combined effect of low-molecular-weight organic acids and creosote on phosphatase activities in sandy soil
2018
This paper assesses the impact of creosote and low-molecular-weight organic acids (LMWOAs) on the activity of acid phosphomonoesterase, alkaline phosphomonoesterase, phosphotriesterase, and inorganic pyrophosphatase in soil. The experiment was carried out on loamy sand samples with organic carbon content of 8.71 g · kg -1 , with the following variable factors: dosages of creosote: 0, 0.5%, and 2.5%; type of LMWOAs: oxalic acid, tartaric acid, and citric acid in the amount of 50 mmol · kg -1 of soil; days of experiment: 1, 7, 14, 28, 56, 112. Obtained results showed that contamination with creosote caused decrease in the activity of soil phosphatases. The observed effect did not always incre…
Is a seminar based on student-created screen capture videos a meaningful way of learning?
2008
We ran a problem-based seminar with screen capture videos. The students worked in small groups of two or three students or they completed the coursework individually. In this seminar the students had a workspace in the Optima environment for publishing their coursework videos. At the final phase of the course the students were expected to familiarize themselves with the presentations of other groups. In this paper we analyze the benefit of our problem-based coursework on the web by comparing the different phases of it. After each phase the students were expected to analyze the benefit of it for their learning. peerReviewed
Western mediterranean archaeology: chemical element levels in archaeological materials as a methodological tool
2014
Una línea de desarrollo de las investigaciones arqueométricas, objeto de nuestro estudio, que presenta un amplia gama de potenciales aplicaciones metodológicas, al día de hoy conocidas solo en parte, es el análisis de los elementos químicos metálicos y no metálicos, ya sean los elementos mayoritarios, los elementos trazas y, más recientemente, los conocidos como “tierras raras” (por su nombre en inglés, Rare Earth Elements - REEs), que se han revelado útiles en nuestro estudio para la solución de algunos problemas arqueológicos. La posibilidad de poder actuar de forma sistemática, ha ayudado, por un lado, a conocer y desarrollar el potencial de estos elementos y, por otro, ha servido de sop…
Real-world experience with dupilumab in severe asthma: One-year data from an italian named patient program
2021
Raffaele Campisi,1 Claudia Crimi,1 Santi Nolasco,2 Bianca Beghè,3 Leonardo Antonicelli,4 Gabriella Guarnieri,5 Nicola Scichilone,6 Morena Porto,2 Luigi Macchia,7 Giulia Scioscia,8 Maria Pia Foschino Barbaro,8 Alberto Papi,9 Nunzio Crimi1,2 1Respiratory Medicine Unit, A.O.U. Policlinico “G. Rodolico -San Marco”, Catania, Italy; 2Department of Clinical and Experimental Medicine, Section of Respiratory Diseases, University of Catania, Catania, Italy; 3Respiratory Medicine Unit, Department of Medicine, University of Modena and Reggio Emilia, Modena, Italy; 4Allergy Unit, Department of Internal Medicine, Ancona University Hospital, Ancona, Italy; 5Department of Car…
Sex Differences in the Physiological Network of Healthy Young Subjects
2021
Within human physiology, systemic interactions couple physiological variables to maintain homeostasis. These interactions change according to health status and are modified by factors such as age and sex. For several physiological processes, sex-based distinctions in normal physiology are present and defined in isolation. However, new methodologies are indispensable to analyze system-wide properties and interactions with the objective of exploring differences between sexes. Here we propose a new method to construct complex inferential networks from a normalization using the clinical criteria for health of physiological variables, and the correlations between anthropometric and blood tests b…
Multispēlētāju un individuālo spēļu dalībnieku afekta atšķirības
2018
Pētījuma mērķis bija noskaidrot, vai multispēlētāju grupas dalībniekiem pozitīvā afekta rādītāji būs augstāki, bet negatīvā afekta rādītāji zemāki nekā individuālā režīma spēļu dalībniekiem. Šī pētījuma ietvaros tika pārbaudīti līdzīgu pētījuma rezultāti. Afekta novērtējumam tika izvēlēta I-PANAS-SF aptauja, kas novērtē indivīdu afektīvos stāvokļus gan interperosnālā, gan intrapersonālā līmenī. Pētījuma izlasi pārstāvēja nejauši izvēlēti 86 respondenti, vecumā no 18 līdz 28 gadu vecumam. Izvirzītā hipotēze apstiprinājās daļēji, jo galvenajās skalās, kas ir pozitīvais un negatīvais afekts, nebija statistiski nozīmīgas atšķirības. Savukārt ieinteresētības un aktivitātes skalās tika pamanītas …
Autentiskie video materiāli runātprasmju pilnveidei 8. klasē
2016
Diplomdarba mērķis bija pārbaudīt, kā autentiskie video materiāli ietekmē runāšanas prasmes 8. klasē. Diplomdarba autors uzskata, ka spēja izteikt viedokli ir prasme, kuru katram studentam vajadzētu prast pielietot. Turklāt, teorijas avoti apstiprina to, ka autentiskie video var iespaidot runāšanas prasmes. Izvēlētā pētījuma metode bija atsevišķa gadījuma pētījums Valsts Ģimnāzijā. Datu vākšanas metodes bija anketa, pašvērtējuma lapa skolēniem un vērtēšanas kritēriji, ko dokumentēja darba autors. Lai pārbaudītu autentisko video ietekmi, tika novadītas 3 stundas. Pētījuma rezultāti atklāja, ka skolēniem patika strādāt ar autentiskiem materiāliem un viņi velējās izpaust savu viedokli angļu va…
DESIGN OF SF3B1 SUBUNIT MODULATORS OF THE SF3B SPLICEOSOME COMPLEX
2022
The subject of this dissertation is the search for new therapeutic strategies for pancreatic cancer and aims to implement a Drug Discovery process for the rational design and synthesis of molecules active in the modulation of pathways related to the regulation of pre-mRNA splicing process. This research project is the result of a joint PhD between the University of Palermo, Italy, and the Department of Medical Oncology, VU University Medical Center, Amsterdam, The Netherlands. It integrates complementary skills in pharmaceutical chemistry and translational cancer research with a special focus on the rational design of new anticancer compounds potentially active on SF3B1 (Splicing Factor 3B …