Search results for "EPA"
showing 10 items of 8995 documents
Treating chronic hepatitis C in daily practice with PEG-IFN alfa2B and ribavirin. An Italian multicentre study
2004
Retreatment with pegylated interferon plus ribavirin of chronic hepatitis C non-responders to interferon plus ribavirin: A meta-analysis.
2009
BACKGROUND/AIMS: Efficacy of retreatment with pegylated interferon (PEG-IFN) plus ribavirin of non-responders to standard or pegylated IFN plus ribavirin has been assessed in various studies, but sustained virologic response (SVR) rates are variable and factors influencing efficacy and tolerability still remain incompletely defined. We aimed to focus on SVR rates and to identify factors influencing them in this meta-analysis. METHODS: MEDLINE as well as a manual search were used. Studies were included if they were controlled or uncontrolled trials, if they had been published as full-length papers and if they included non-responders to standard or pegylated IFN and ribavirin therapy. Fourtee…
La tributación de la pensión compensatoria como consecuencia de la separación o divorcio en españa
2016
The compensation pension is provided for in the Civil Code for cases of separation or divorce in which there are an economic imbalance between the former spouses. This institution generates tax consequences for the taxpayer who paid compensation as well as for the recipient. This article presents and analyzes the tax regime for ex-spouses derived as a result of the establishment of the compensation pension. La pensión compensatoria está contemplada en el Código Civil para los casos de separación o divorcio en los que se produce un desequilibrio económico en entre los excónyuges. Esta institución genera unas consecuencias fiscales para el obligado tributario que debe abonar la compensación, …
Finnish Health Care Professionals’ Views of Patients Who Experience Family Violence
2015
1. Inka Koistinen[1][1] 2. Juha Holma[1][1] 1. 1University of Jyvaskyla, Finland 1. Juha Holma, Department of Psychology, Psychotherapy Training and Research Center, University of Jyvaskyla, P.O. Box 35, Jyvaskyla, 40014 Finland. Email: juha.m.holma{at}jyu.fi The aim of this study was to examine the beliefs health care personnel have about patients who experience family violence. This was done by analyzing the positions constructed for such patients using content analysis. The data comprise six focus groups conducted with physicians, nurses, social workers, and psychologists working in a maternity unit, a psychiatric ward, and an emergency department. The research team collected the data in…
Buccal Thin Films as Potent Permeation Enhancers for Cytisine Transbuccal Delivery
2022
Cytisine (CYT) is a powerful anti-smoking compound which could greatly benefit from transbuccal delivery because of both its unfavorable pharmacokinetics after oral administration and its intrinsic ability to permeate the buccal mucosa. This work aims to design CYT-loaded buccal thin films suitable for transbuccal drug delivery due to its capability of promoting the interaction between CYT and the buccal membrane. The solvent casting method was employed to prepare several thin films combining various excipients such as matrixing polymers, mucoadhesion agents, plasticizers and other compounds as humectants and sweeteners, component ratios and solvents. A total of 36 compositions was prepared…
Personu, kurām ir tiesības uz aizstāvību, liecības kriminālprocesā
2020
Bakalaura darba tēma “Personu, kurām ir tiesības uz aizstāvību, liecības kriminālprocesā” sniedz vispārīgu ieskatu personu, kurām ir tiesības uz aizstāvību procesuālo statusu un šo personu sniegto liecību izpratnē. Darbā tiek apskatīta personu, kurām ir tiesības uz aizstāvību liecību iegūšanas veidi un šo personu kriminālprocesuālās tiesības attiecībā uz liecību sniegšanu kriminālprocesa gaitā. Darba ietvarā ir apskatīti un analizēti gaidāmie fundamentālie grozījumi attiecībā uz personām, kurām ir tiesības uz aizstāvību liecību saturu, nosakot, ka personām, kurām ir tiesības uz aizstāvību, būs jāsniedz patiesas liecības, ja tās izmantos savas tiesības liecināt.
Adapter un portage de repas à l'appétit et à l'état nutritionnel de personnes âgées dépendantes : une étude clinique de 4 mois
2020
Avec l'âge, la capacité des personnes âgées à réaliser les tâches du quotidien, notamment celles reliées à l'alimentation (courses, préparation des repas), peut être altérée. En France, face à cette situation, de plus en plus de personnes âgées font appel à des services de livraison de repas à domicile. Les objectifs de cette étude sont de caractériser le statut nutritionnel des personnes âgée, faisant appel à ce type de service et de mesurer l'impact d'une intervention nutritionnelle adaptée, en personnalisant leur livraison de repas à leurs besoins. 64 personnes âgées, bénéficiant d'une livraison de repas à domicile ont été recrutés et répartis au hasard dans un groupe expérimental (n=32 …
A robust reprogramming strategy for generating hepatocyte-like cells usable in pharmaco-toxicological studies.
2023
Abstract Background High-throughput pharmaco-toxicological testing frequently relies on the use of established liver-derived cell lines, such as HepG2 cells. However, these cells often display limited hepatic phenotype and features of neoplastic transformation that may bias the interpretation of the results. Alternate models based on primary cultures or differentiated pluripotent stem cells are costly to handle and difficult to implement in high-throughput screening platforms. Thus, cells without malignant traits, optimal differentiation pattern, producible in large and homogeneous amounts and with patient-specific phenotypes would be desirable. Methods We have designed and implemented a no…
Lessons learnt from the COVID-19 pandemic: results of EAHP survey on the future crisis preparedness of hospital pharmacies
2021
Aim The present survey aimed to collect information on the lessons learnt from the COVID-19 pandemic by hospital pharmacists. It focused on the shortages of health goods and the experiences of hospitals during the first phase of the crisis. Methods A 17-question survey was conducted by EAHP, looking at the experiences of hospital pharmacists during the COVD-19 pandemic. The survey ran from 16 September to 23 December 2020. Statistical analysis included backward stepwise logistic regression (BSLR), Pearson’s χ2 test, t-test and one-way ANOVA, as appropriate; p≤0.05 was considered statistically significant. Results 1466 hospital pharmacists answered the survey fully. 58%, 63% and 69% of them …
Appropriateness of requests for human serum albumin at the University Hospital of Palermo, Italy: a prospective study
2015
Abstract OBJECTIVE: First, to assess the appropriateness of requests for albumin using current guidelines; second, to evaluate physicians' compliance with this protocol. DESIGN: Descriptive, prospective study. SETTING: 'Paolo Giaccone' University Hospital in Palermo (Italy). PARTICIPANTS: The six departments with the highest orders for albumin. INTERVENTION: An experimental, pharmacist-driven process for daily orders of albumin was activated over a period of 1 month. Pharmacy personnel handed out order forms on six different wards. Physicians were required to select one of a number of intended uses listed on the form. MAIN OUTCOME MEASURES: Data on albumin and serum protein levels; number o…