Search results for "EPO"
showing 10 items of 6062 documents
An Example: Money
1995
The institution of money, like that of language, or that of the State, has often been seen to be based on some kind of contractual agreement. Aristotle describes the nature of money as follows: Money has become by convention a sort of representative of demand; and that is why it has the name ‘money’ (nomisma) because it exists not by nature but by law (nomos) and it is in our power to change it and make it useless. (Ethica Nicomachea, V.5.II33a) The word nomos is ambiguous: in another translation of Ethica it has been translated as “custom”. This ambiguity reflects a theoretical problem in the classical social theory: money has been seen either as a result of an act of will of the legislato…
Money and the natural rate of interest: structural estimates for the United States and the Euro area
2008
We examine the role of money, allowing for three competing environments: the New Keynesian model with separable utility and static money demand; a non-separable utility variant with habit formation; and a version with adjustment costs for holding real balances. The last two variants imply forward-looking behavior of real money balances, as it is optimal for agents to allow their forecast of future interest rates to affect current portfolio decisions. We distinguish between these specifications by conducting a structural econometric analysis for the U.S. and the euro area. FIML estimates confirm the forward-looking character of money demand. Using these estimates we find that, in response to…
Efecto de los antagonistas de los receptores de endotelina sobre el remodelado y reactividad de la arteria pulmonar en pacientes EPOC: estudio funcio…
2015
En la presente Tesis Doctoral se tratan los efectos del bosentan, antagonista dual de los receptores de endotelina - 1, sobre la apoptosis y la expresión de receptores de endotelina inducidas por extracto de humo de cigarrillo en células endoteliales y células de músculo liso de arteria pulmonar humana. Para ello nos centramos en la importancia clínica del la combinación de dos enfermedades de las vías aéreas íntimamente relacionadas y su tratamiento conjunto (la EPOC y la Hipertensión Arterial Pulmonar severa). La hipertensión arterial pulmonar (PAH) es una complicación común de la enfermedad crónica obstructiva pulmonar (EPOC) que cursa con vasoconstricción pulmonar, producida por hipoxia…
Incorporation and metabolism of trans 20∶5 in endothelial cells. Effect on prostacyclin synthesis
2000
To study the ability of long-chain trans fatty acids (FA) to be incorporated and metabolized into endothelial cells, bovine aortic endothelial cells were incubated with medium enriched eicosapentaenoic acid (EPA) bound to albumin (M2) or one of its geometrical isomers: 20:5 5c,8c,11t,14c,17c (M3), 20:5 5c,8c,11c,14c,17t (M4), or 20:5 5c,8c,11t,14c,17t (M5). After 48 h of incubation, supernatant and cells were harvested and their lipids were analyzed, including prostacyclin synthesis. EPA and 22:5n-3 of endothelial cells incubated with M2 were, respectively, three and two times higher than in control cells (incubated in M1, without any fatty acid added), whereas 22:6n-3 increased only in the…
Instrumentation in sports biomechanics
2007
La biomecánica deportiv emplea una serie de herramientas y técnicas de instrumentación paara el análisis de las diferentes disciplinas físico-deportivas, así como también para el desarrollo de nuevos materiales y equipamiento deportivo. Sin embargo, estas herramientas empleadas actualmente, poseen su cuerpo de conocimientos teóricos en los conocidos como "precursores de la biomecánica". Aristóteles, Da Vinci, Galileo, Descartes, Borelli, Newton, etc... El documento, presenta diferentes técnicas instrumentales desarrolladas para evaluar y aportar información relevante en la ejecución físico-deportiva, así como contribuir en la disminución de la epidemiología deportiva. Entre las principales …
Cutting Tool Materials
2008
This chapter provides the state-of-the-art materials engineering sector that produces cutting tool materials for different manufacturing branches. It highlights the special demands on this special material group for modern machining technologies. Five groups of cutting tool materials are characterized in terms of their mechanical and thermo-physical properties: high-speed steels, sintered tungsten carbides, cermets, ceramics and superhard materials, all as conventional (uncoated) and coated grades. The most popular techniques of coating deposition on various substrates are described. Practical examples of cutting tool inserts made of various materials produced by leading world manufacturers…
Increasing understanding and confidence in THM simulations of engineered barrier systems
2020
Previous studies on the modelling of coupled thermo-hydro-mechanical (THM) processes in bentonite-based engineered barrier systems (EBSs) showed the sensitivity of the output quantities to changes in the input parameters. To investigate the effects of uncertainties on the modelling results, to improve the understanding of the coupled processes active in the repository near field and to gain in-depth understanding of model uncertainties of different codes, a sensitivity analysis and code comparison of EBS simulations was performed within the Task Force on Engineered Barrier Systems. The analysis included variations in material parameter values, boundary and initial conditions, considered phy…
Credit reporting e intermediazione creditizia: scelte di “make or buy” tra relationship e transaction banking.
2016
Il presente lavoro prende in esame, con una prospettiva di analisi economico-aziendale, il ruolo del mercato del credit reporting nell’esercizio della funzione creditizia delle banche, nonche il vario articolarsi delle scelte di make-or-buy informativo nella catena del valore dell’intermediazione creditizia, tra approcci di relazione di clientela di tipo relationship banking e transaction banking. In particolare, il lavoro e volto a sistematizzare le teorie ed a comprendere le determinanti del ricorso delle banche al mercato dell’informazione creditizia. Il paper e strutturato nel modo seguente. La sezione 2 introduce il tema dell’economia dell’informazione nel mercato creditizio. La sezion…
Energy saving in airports by trigeneration. Part II: Short and long term planning for the Malpensa 2000 CHCP plant
2006
With reference to the feasibility analysis for CHCP applications in airports performed in Part I of this work, the optimal strategy for repowering and operation of the Malpensa 2000 CHCP plant is here discussed. The analysis starts from experimental energy demand data, available on hourly basis for an entire operational year. After a description of the CHCP lay-out, the optimal management strategy was determined keeping into account the articulated energy tariff system and the technical characteristics of components. A profit-oriented optimization of the repowering actions to take up to 2010 is presented, based on the expected growth of energy consumption due to the scheduled increases in t…
An integrated model for physical-biological wastewater organic removal in a submerged membrane bioreactor: Model development and parameter estimation
2008
The paper presents the setting up of a mathematical model for membrane bioreactor able to simulate physical-biological wastewater organic removal. The model is basically divided into two sub-models: the first sub-model is basically devoted for the simulation of the biological features and the second one for the physical processes. In particular regarding the biological aspects, the ASM concept has been employed. On the other hand, the physical processes have been modelled considering the deep-bed theory taking into account not only the effect of the physical membrane filtration but also the cake layer effect. This latter operates as a biological membrane leading to a further reduction of th…