Search results for "EPO"
showing 10 items of 6062 documents
Integrated CGH/WES Analyses Advance Understanding of Aggressive Neuroblastoma Evolution: A Case Study
2021
Neuroblastoma (NB) is the most common extra-cranial malignancy in preschool children. To portray the genetic landscape of an overly aggressive NB leading to a rapid clinical progression of the disease, tumor DNA collected pre- and post-treatment has been analyzed. Array comparative genomic hybridization (aCGH), whole-exome sequencing (WES), and pharmacogenetics approaches, respectively, have identified relevant copy number alterations (CNAs), single nucleotide variants (SNVs), and polymorphisms (SNPs) that were then combined into an integrated analysis. Spontaneously formed 3D tumoroids obtained from the recurrent mass have also been characterized. The results prove the power of combining C…
Quality Control in 3D Printing: Accuracy Analysis of 3D-Printed Models of Patient-Specific Anatomy
2021
As comparative data on the precision of 3D-printed anatomical models are sparse, the aim of this study was to evaluate the accuracy of 3D-printed models of vascular anatomy generated by two commonly used printing technologies. Thirty-five 3D models of large (aortic, wall thickness of 2 mm, n = 30) and small (coronary, wall thickness of 1.25 mm, n = 5) vessels printed with fused deposition modeling (FDM) (rigid, n = 20) and PolyJet (flexible, n = 15) technology were subjected to high-resolution CT scans. From the resulting DICOM (Digital Imaging and Communications in Medicine) dataset, an STL file was generated and wall thickness as well as surface congruency were compared with the original …
Präpositionale Wortgruppen im Altspanischen: 13.-15. Jahrhundert
2013
Der Untersuchungsgegenstand dieser Dissertation sind präpositionale Wortgruppen (PWG) (locuciones prepositivas) in kastilischen Texten aus dem Mittelalter. Ziel dieser Arbeit ist eine kontrastive Analyse von PWG an Hand von zwei Diskurstraditionen, einer juristischen und einer historischen, während des 13., 14. und 15.Jahrhunderts. Das Hauptkorpus beinhaltet zu jedem Jahrhundert einen juristischen und einen chronistischen Text. Um der Gefahr der einseitigen Konzentration auf juristische und chronistische Texte zu entgehen, werden für jedes Jahrhundert ein zusätzlicher Text aus der Gattung der Literatur ausgewertet (Calila e Dimna, El Conde Lucanor und La Celestina). Ausgangspunkt dieser Arb…
Israel. Política económica en Israel
2018
This document presents the forecast of macroeconomic developments compiled from different sources as World Bank, International Monetary Fund, Bank of Israel, OECD, etc., in December 2018 regarding the main macroeconomic variables—GDP, inflation, unemployment, foreign trade and the real growth rate. According to international institutions staff forecast, gross domestic product (GDP) and other main macroeconomic indicators are projected till 2018 final results. We analyse the main economic data for a five years period in order to study the yearly results of the economy of Israel. Este documento presenta el pronóstico del desarrollo macroeconómico general de Israel, a parti…
Crystal structure of 12-benzylsulfanyl-2,9-dibromo-6H-dibenzo[b,g][1,8]naphthyridin-11-one
2015
The hetero-tetra-cene skeleton of the title mol-ecule, C23H14Br2N2OS, is defined by linear annulation of four six-membered rings, including two N heteroatoms. This moiety is nearly planar (r.m.s. deviation = 0.055 Å), with a slight twist of 4.1 (2)° between the two halves of the aromatic system. The dihedral angle between the least-squares plane of the skeleton and the benzyl group is 24.5 (3)°; the C-S-C angle involving the benzyl-sulfanyl group is 99.2 (4)°. In the crystal, mol-ecules are π-stacked in an anti-parallel fashion along [110], with a distance between the aromatic planes of 3.47 (2) Å. Inter-molecular N-H⋯O hydrogen bonds form chains extending parallel to [001] and bridge the a…
Treatment of a stage III rima glottidis patient with the oncolytic virus Rigvir: A retrospective case report: Erratum.
2019
Abstract Rationale: Of all the parts of the larynx, the glottis has the highest frequency of cancer. With disease progression, the vocal cord movement is affected and for advanced stages its anatomical and functional preservation is rarely achievable, if at all. Patient concerns: Here we describe a 72-year-old patient who presented with hoarseness for a year and was only able to whisper. Diagnosis: A computed tomography (CT) scan of the vocal cords (without contrast) showed higher density tissue. Histological examination disclosed a well-differentiated verrucous squamous cell carcinoma of the glottis. Interventions: The patient was treated with the oncolytic ECHO-7 virus Rigvir without any …
¿Hay beneficios psicosociales por la práctica Pilates? Un análisis de la literatura científica
2014
En los últimos 5 años, las bases de datos analizadas muestran un notable incremento en el número de publicaciones sobre Pilates. La enorme difusión y popularidad del método Pilates podría deberse a los beneficios físicos, psíquicos y sociales que las personas podrían obtener con su práctica. Desde el ámbito científico, existe la necesidad de actualizar y evaluar objetivamente los resultados ya existentes sobre los posibles beneficios que puede producir la práctica de Pilates sobre la salud. Esta revisión, pretende comprobar si hay una su%ciente fundamentación científica que justifique sus beneficios en la salud psicológica de los practicantes de Pilates. Para ello se ha realizado una búsque…
Use of a Perioperative Web-Based Exercise Program for a Patient with Barrett’s Carcinoma Scheduled for Esophagectomy
2019
A poor preoperative functional capacity increases the perioperative risk. Therefore, a web-based exercise approach has been initiated for a careful supervision and individual support of patients during their perioperative cancer therapy. Here, we present the data of a 57-year-old patient, scheduled for esophagectomy. Beside a five-week neoadjuvant chemoradiotherapy (CRT), the patient performed 10 weeks of a web-based prehabilitation exercise training (preconditioning) and continued the exercise program for 14 weeks after surgery. The patient performed 42 of 44 recommended training sessions in the preconditioning period in his home environment. This corresponds to a mean of 131 (±38) min of …
CCDC 1575390: Experimental Crystal Structure Determination
2017
Related Article: V. Piccialli, A. Tuzi, R. Centore|2017|Acta Crystallogr.,Sect.E:Cryst.Commun.|73|1603|doi:10.1107/S2056989017013391
Estudio cineantropométrico, nutricional y ergogénico de deportistas de triatlón
2019
La evaluación antropométrica y nutricional de triatletas es una herramienta fundamental en el ámbito deportivo no sólo para estimar el estado de salud, sino para mejorar la calidad de vida, e incluso en determinar posibles talentos deportivos. La presente tesis se encuentra enfocada en triatletas provenientes de la Federación de Triatlón de la Comunidad Valenciana, con una media (DE) de edad de 25,0 (6,5) años, a los cuales se les realizó, previo explicación del estudio y obtención del consentimiento informado, la determinación del perfil restringido, de acuerdo a los criterios de medición y de referencia de la Sociedad Internacional para el Avance de la Cineantropometría (International Soc…