Search results for "EPO"

showing 10 items of 6062 documents

Decompression induces inflammation but do not modify cell proliferation and apoptosis in odontogenic keratocyst

2022

Background Odontogenic keratocyst (OKC) is a development cyst, of odontogenic origin, that differs from other entities by its infiltrating and aggressive biological behavior. Among conservative treatments for large lesions, surgical decompression stands out, with a variable recurrence rate. Aim: To evaluate the histological effects of decompression treatment on OKC, including cell proliferation and apoptosis of epithelial cyst. Material and Methods 21 OKC cases were included. Samples were taken before and after surgical decompression for histological evaluation and immunohistochemical staining of Ki-67, MCM4/7, Bax and Bcl2. Data were analyzed and compared using Student’s t and Wilcoxon tes…

musculoskeletal diseasesBcl2QUISTES ODONTOGENICOSOperative DentistryKi-67Case ReportApoptosisMCMDecompression.General DentistryOdontogenic keratocystUNESCO:CIENCIAS MÉDICAS
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Comparisons of processing and strength properties of two adhesive systems for composite joints

2007

Abstract In the present study rheological, static and impact tests are carried out on two adhesive resins usually employed in marine applications; then single lap joint tests are conducted on composites joints evidencing the effect of the curing time of both resins on the mechanical properties of the joint. The applicability and workability conditions of the adhesive resins are determined evaluating the curing evolution by a preliminary rheological analysis; then the relation of curing properties with the mechanical performances of the resins themselves and with ones of the composite joints is estimated. Static flexural and Izod impact tests are performed on the resins at increasing time af…

musculoskeletal diseasesCuring timeMaterials sciencePolymers and PlasticsAdhesive bondingGeneral Chemical EngineeringComposite numberIzod impact strength testEpoxySingle lap shear testBiomaterialsStructural adhesiveSettore ING-IND/22 - Scienza E Tecnologia Dei MaterialiLap jointFlexural strengthvisual_artvisual_art.visual_art_mediumAdhesiveComposite materialCuring (chemistry)International Journal of Adhesion and Adhesives
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Arthroscopic approach for treating a pigmented villonodular sinovitis of TMJ. A case report

2017

The present report describes the case of a 29-year-old man referred to our service for TMJ pain and progressive reduction of the mouth opening. Differential diagnostics included rheumatologic diseases, monoarthritis and intraarticular lumps. In this line, a face CT scan and a MRI of TMJ were carried out in order to ensure a proper diagnosis. These tests showed a solid lesion into the joint cavity. In view of that, we decided to perform a diagnostic and therapeutic arthroscopy of TMJ. Histopathological studies confirmed the diagnosis of pigmented villonodular synovitis. The main aim of this report is to describe this rare syndrome with the goal of proposing suitable treatments. Moreover, we …

musculoskeletal diseasesJoint cavitymedicine.medical_specialtyOral Medicine and Pathologymedicine.diagnostic_testbusiness.industryComputed tomographyCase ReportOdontología:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludSurgeryMouth openingstomatognathic systemTherapeutic arthroscopyPigmented villonodular synovitisUNESCO::CIENCIAS MÉDICASMonoarthritismedicineRare syndromebusinessGeneral Dentistry
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Ultrasound-guided percutaneous treatment of a calcific acromioclavicular joint

2020

Abstract Rationale: Calcific tendinopathy is one of the most frequent causes of nontraumatic shoulder pain. However, intra-articular calcifications appear to be an infrequent condition. We herein report a rare case study of an intra-articular calcification of the acromioclavicular joint. Patient concerns: A 46-year-old man presented with an acute pain in the anterior superior region of the left shoulder which also radiated to the left cervical region. The man during the physical evaluation also presented severe functional limitation of the shoulder movements in all planes of motion. Diagnoses: The diagnosis was carried out through a radiographic and an echotomographic examination, highlight…

musculoskeletal diseasesMaleacromioclavicular joint ;ultrasound-guided percutaneous treatmentshoulderCalcinosisMiddle Aged6300Acromioclavicular JointTendinopathyHumanspainClinical Case ReportUltrasonography InterventionalResearch ArticleMedicine
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Lymphatic vessels of the dura mater: a new discovery?

2015

Aspelund et al. discover the presence of a lymphatic vessel network in the dura mater of the mouse brain and show that these dural lymphatic vessels are important for the clearance of macromolecules from the brain.

musculoskeletal diseasesPathologymedicine.medical_specialtyHistologyMacromolecular SubstancesDura materCentral nervous systemNeuroimmunologyBlood–brain barrierBlood-brain barrier; Brain; Central nervous system; Dura mater; Lymphatics; Mascagni; Neuroanatomy; Neuroimmunology; Transudate; Anatomy; Histology; Developmental Biology; Ecology Evolution Behavior and Systematics; Molecular Biology; Cell BiologyTransudateLymphatic SystemMatters ArisingmedicineAnimalsDura materMolecular BiologyEcology Evolution Behavior and SystematicsBlood-brain barrierCerebrospinal Fluidintegumentary systembusiness.industrySettore BIO/16 - Anatomia UmanaBrief Definitive ReportMascagniBrainExtracellular FluidAnatomyCell Biologymusculoskeletal systemEcology Evolution Behavior and SystematicTransudatenervous system diseasesNeuroanatomyNeuroimmunologymedicine.anatomical_structureLymphatic systemnervous systemCentral nervous systemLymph NodesAnatomybusinessLymphaticNeuroanatomyDevelopmental BiologyJournal of anatomy
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Consequences of Justifications of Assessments in French Expanded Audit Reports

2018

Since 2003, French auditors must disclose justifications of assessments (JOAs) in expanded audit reports. Like critical audit matters recently introduced in the US and key audit matters introduced by international standard setters, the purpose of JOAs is to enhance the informative value of audit reports. Based on French audit reports issued from 2002 to 2011, we analyze the impact of first-time implementation of JOAs, and the impact of new JOAs in subsequent years, on investors (measured by abnormal returns and abnormal trading volume) and on the audit (measured by audit report lag, abnormal accruals, and audit fees). For both first-time implementation of JOAs and new JOAs in subsequent yea…

musculoskeletal diseasesQuality auditAuditor's reportAccrualbusiness.industryhealth services administrationInternational standardMarket reactionAccountingBusinessAuditmusculoskeletal systemhumanitiesSSRN Electronic Journal
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Non-healing tongue ulcer in a rheumatoid arthritis patient medicated with leflunomide. An adverse drug event?

2017

Leflunomide is a member of the disease modifying anti-rheumatic drugs group used as a treatment modality in active rheumatoid and psoriatic arthritis. “Oral ulcers” are reported in 3-5% of leflunomide medicated rheumatoid arthritis patients with adverse events, but they are not described in detail in the literature. We present a case of an ulcer in the tongue of a rheumatoid arthritis patient managed with leflunomide and contemplate on its pathogenesis. Key words:Leflunomide, oral ulcer, DHODH.

musculoskeletal diseasesmedicine.medical_specialtyCase ReportOdontologíaDisease030207 dermatology & venereal diseases03 medical and health sciencesPsoriatic arthritis0302 clinical medicineTonguemedicineOral ulcersskin and connective tissue diseasesAdverse effectGeneral DentistryLeflunomide030203 arthritis & rheumatologyOral Medicine and Pathologybusiness.industry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseCiencias de la saludDermatology3. Good healthSurgerymedicine.anatomical_structureAdverse drug eventRheumatoid arthritisUNESCO::CIENCIAS MÉDICASbusinessmedicine.drugJournal of Clinical and Experimental Dentistry
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Impingement of the Sciatic Nerve due to a Protruding Acetabular Cage Rim

2020

Abstract Sciatic nerve damage is a well-known complication that occurs in 1.5% of patients after primary total hip arthroplasty and in 8% after revision total hip arthroplasty. Yet when considering re-revision arthroplasty and acetabular cage implantation, incidence and management remain unclear. This case report describes a young female patient with sciatic nerve impingement after acetabular cage implantation. Her primary complaint was shooting sciatic left leg pain, worsening on ambulation and when seated. A complete workup was negative for spinal impingement or infection, and axonal nerve damage was confirmed through nerve conduction studies. The intraoperative findings showed that it wa…

musculoskeletal diseasesmedicine.medical_specialtyComplicationsRevisionmedicine.medical_treatmentAcetabular cageCase Report03 medical and health sciences0302 clinical medicinelcsh:Orthopedic surgeryMedicineOrthopedics and Sports Medicine030212 general & internal medicineYoung female030222 orthopedicsbusiness.industryA diamondArthroplastySurgerylcsh:RD701-811SurgeryTotal hip arthroplastySciatic nerveMotor palsybusinessComplicationNerve conductionCageTotal hip arthroplastyArthroplasty Today
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Association between Serum Osteoprotegerin Levels and Severity of Coronary Artery Disease in Patients with Acute Myocardial Infarction

2021

International audience; Background. Osteoprotegerin (OPG), a glycoprotein of the tumour necrosis factor (TNF) superfamily, is one of the main biomarkers for vascular calcification. Aim. We aimed to evaluate the association between serum OPG levels and extent of coronary lesions in patients with acute myocardial infarction (MI). Methods. Consecutive patients hospitalized for an acute MI who underwent coronary angiography were included. SYNTAX score was calculated to assess the severity of coronary artery disease. The population was analysed in low (5 (3–6)), medium (11 (9–13)) and high (20 (18–23)) tertiles of SYNTAX score. Results. Among the 378 patients included, there was a gradual increa…

musculoskeletal diseasesmedicine.medical_specialtyNecrosisPopulationRenal function030204 cardiovascular system & hematologyCoronary artery disease03 medical and health sciences0302 clinical medicineOsteoprotegerin[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemDiabetes mellitusInternal medicinemedicineMyocardial infarction030212 general & internal medicineeducation030304 developmental biology0303 health scienceseducation.field_of_studyEjection fractionbusiness.industryBrief ReportRGeneral Medicinemedicine.diseaseSYNTAX scoremyocardial infarctionosteoprotegerinvascular calcificationCardiologyMedicinemedicine.symptombusinessCardiology and Cardiovascular Medicinecoronary artery diseaseJournal of Clinical Medicine
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Self-reported flares are predictors of radiographic progression in rheumatoid arthritis patients in 28-joint disease activity score remission: a 24-m…

2016

Background Disease flares are common in rheumatoid arthritis (RA) and are related to structural damage. However, few data on the impact of flares reported by patients on radiographic progression are available. Our aim was to investigate whether overall flares (OF), self-reported flares (SRF) and short flares assessed at the visit (SF) predict radiographic progression in RA patients in DAS28 (28-joint disease activity score) remission. Methods We reviewed the records of RA patients included in our database. We considered all patients who had a period of at least 24 months in remission (DAS28 0. Patients were assessed every 3 months and flares were recorded. We defined SRF as any worsening of…

musculoskeletal diseasesmedicine.medical_specialtyRadiographic progressionRadiographyDiseasenot knownDisease activity03 medical and health sciencesJoint disease0302 clinical medicineInternal medicineDAS28 remissionmedicine030212 general & internal medicineRheumatoid arthritisskin and connective tissue diseases030203 arthritis & rheumatologybusiness.industryFlaresmedicine.diseaseRheumatologyBiologic treatment; DAS28 remission; Flares; Radiographic progression; Rheumatoid arthritis; Self-reported flaresRheumatoid arthritisOrthopedic surgeryPhysical therapyObservational studybusinessBiologic treatmentSelf-reported flaresResearch ArticleArthritis Research & Therapy
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