Search results for "EPOR"
showing 10 items of 2839 documents
L’architettura gotica in Sicilia centro-orientale nelle perizie degli architetti d’età moderna
2018
L’ARCHITETTURA GOTICA IN SICILIA CENTRO-ORIENTALE NELLE PERIZIE DEGLI ARCHITETTI D’ETÀ MODERNA Il contributo si concentra sulla percezione e sulla valutazione da parte degli architetti siciliani d’età moderna di opere costruite sull’isola in età gotica. L’occasione del confronto emerge soprattutto dalle perizie redatte durante l’elaborazione di nuovi progetti (di ammodernamento, di completamento) che contemplano la salvaguardia o la distruzione delle strutture del passato. Le relazioni selezionate in questa occasione affrontano pertanto questioni di carattere prevalentemente estetico e di linguaggio, ma anche le ragioni inerenti alle strutture e quelle relative alle economie (di cantiere, d…
The professional report in initial teacher training in France. Le «mémoire professionnel» dans la formation initiale des enseignants en France
2007
07086; International audience; While the IUFM (University Institutes for Teachers' Training) are going to become part of universities, this article questions one of the bases validating the teachers' training: the professional report. This assessment concerns exercising teachers in having a critical mind towards their practical experience, because its purpose is to prepare teachers to adapt to the different types of pupils they are going to teach. This is the reason why the Government can only define this assessment briefly, even if they want to have better control over the teachers' training. To be precise concerning this assessment, the Government has to trust the teachers' trainers' cont…
Multiple granular cell tumors with metachronous occurrence in tongue and vulva. Clinicopathological and immunohistochemical study
2014
Granular cell tumor (GCT) usually occurs as a single tumor, although sometimes multiple lesions can occur. In present report we analyze the clinicopathological and immunohistochemical features of a multiple GCT involving the tongue of a 14-year-old girl, with no other abnormalities, with a metachronous occurrence of a second GCT in vulva, after a period of 10 years. Both tumors revealed S-100, vimentin and CD57 positivity. In addition, over expression of calretinin was observed in tumor cells located in the vicinity of pseudoepitheliomatous hyperplasia (PEH) of the tongue. Tumor vasculature situated close to the PEH showed marked CD105 reactivity, data not described so far, suggesting an in…
A stress-responsive miRNA regulates BMP signaling to maintain tissue homeostasis
2021
Adult organisms must sense and adapt to environmental fluctuations. In high-turnover tissues such as the intestine, these adaptive responses require rapid changes in gene expression that, in turn, likely involve posttranscriptional gene control. However, intestinal-tissue-specific microRNA (miRNA)-mediated regulatory pathways remain unexplored. Here, we report the role of an intestinal-specific miRNA, miR-958, that non-cell autonomously regulates stem cell numbers during tissue homeostasis and regeneration in the Drosophila adult midgut. We identify its downstream target cabut, the Drosophila ortholog of mammalian KLF10/11 transcription factors, which mediates this miR-958 function by promo…
Grupos empresariales y reportes de sostenibilidad en América Latina
2018
En esta investigación abordamos los reportes de sostenibilidad de los grupos empresariales. La mayoría de los informes de sostenibilidad de las principales compañías alrededor del mundo se elaboran siguiendo las recomendaciones establecidas en el Global Reporting Initiative (GRI) (Ernst & Young, 2017; WBCSD, 2017). Por ello, partiendo de los grupos empresariales del sector real incluidos en GRI Reports List para los países que integran la Alianza del Pacífico y a su vez el Mercado Integrado Latinoamericano –MILA -, esto es Chile, Colombia, México y Perú, aportamos evidencia empírica y contextual en torno a las características y consideraciones que motivan la presentación de los reportes de …
El problema de la etnia tártara en la U.R.S.S.
1992
ESTE ES UN ESTUDIO SOBRE LOS PROBLEMAS AFRONTADOS POR LA NACION TARTARA DE LA PENINSULA DE CRIMEA DESDE SU CONQUISTA POR RUSIA EN EL SIGLO XVIII HASTA LA ACTUALIDAD, CON ESPECIAL HINCAPIE EN LAS VICISITUDES SUFRIDAS DESDE LA REVOLUCION DE OCTUBRE DE 1971 -GUERRA CIVIL, HAMBRES- Y EN LA DEPORTACION EN MASA SUFRIDA EN LOS AÑOS CUARENTA POR ORDEN DE STALIN.
Modulation of base excision repair of 8-oxoguanine by the nucleotide sequence.
2013
8-Oxoguanine (8-oxoG) is a major product of oxidative DNA damage, which induces replication errors and interferes with transcription. By varying the position of single 8-oxoG in a functional gene and manipulating the nucleotide sequence surrounding the lesion, we found that the degree of transcriptional inhibition is independent of the distance from the transcription start or the localization within the transcribed or the non-transcribed DNA strand. However, it is strongly dependent on the sequence context and also proportional to cellular expression of 8-oxoguanine DNA glycosylase (OGG1)-demonstrating that transcriptional arrest does not take place at unrepaired 8-oxoG and proving a causal…
8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) prote…
2008
We have analysed the effect of oxidative guanine lesions on the expression of a transfected reporter gene in mouse embryonic fibroblasts deficient in Cockayne syndrome B protein (Csb) and/or the 8-oxoguanine DNA glycosylase (Ogg1). We used a highly sensitive flow cytometry-based approach and quantitative real-time PCR to measure the changes in gene expression caused by the presence of oxidised guanine residues generated by photosensitisation in the vector DNA. In wild-type cells, small numbers (one or three) of oxidised guanines did not affect gene expression at short times after transfections, whereas progressive reduction of the transgene expression was observed at later time points. Alth…
La Grande Guerra racconta sul giornale "L'Ora"
2020
Il saggio propone alcuni momenti ed episodi del primo anno di guerra, attraverso una piccola campionatura di articoli pubblicati sul quotidiano "L’Ora" di Palermo. riguardanti il 1915. Allo scoppio della prima guerra mondiale il quotidiano fondato da Ignazio Florio è al suo quattordicesimo anno di vita ed è sotto la direzione di Francesco Paolo Mulè. Dallo spoglio effettuato emerge che, accanto alla divulgazione dei resoconti ufficiali giunti da Roma, con il quasi quotidiano accompagnamento dei comunicati del Generale Cadorna dal fronte, vengo- no pubblicate corrispondenze di guerra mutuate dal Corriere della sera e del Mattino. Ci si sofferma in particolare su alcuni reportage di Luigi …
Dydrogesterone use during pregnancy: Overview of birth defects reported since 1977
2009
Between 1977 and 2005, 28 cases of potential links between maternal dydrogesterone use during pregnancy and congenital birth defects were reported. The types of defects were very diverse, with no evidence of a pattern of abnormalities. The data do not provide evidence for congenital malformations associated with dydrogesterone use.