Search results for "ER STRESS"
showing 10 items of 109 documents
Effect of Mycorrhizal Inoculation on Melon Plants under Deficit Irrigation Regimes
2023
The shortage of good quantity and quality of water for irrigated agriculture is a major problem in arid and semiarid regions. To deal with this problem, deficit irrigation (DI) or arbuscular mycorrhizal fungi (AMF) inoculation have been proposed and adopted for many crops as a tool to save water, or to improve crop tolerance to drought stress. An experiment was conducted for two consecutive years to evaluate the effect of mycorrhizal inoculation on the physiological, morphological, yield, and quality characteristics of melon plants grown under deficit irrigation. Melon crop (Cucumis melo L. cv. Helios) was grown under field conditions adopting a split-plot design with four replications, whe…
Hypertrophy and ER Stress Induced by Palmitate Are Counteracted by Mango Peel and Seed Extracts in 3T3-L1 Adipocytes
2023
A diet rich in saturated fatty acids (FAs) has been correlated with metabolic dysfunction and ROS increase in the adipose tissue of obese subjects. Thus, reducing hypertrophy and oxidative stress in adipose tissue can represent a strategy to counteract obesity and obesity-related diseases. In this context, the present study showed how the peel and seed extracts of mango (Mangifera indica L.) reduced lipotoxicity induced by high doses of sodium palmitate (PA) in differentiated 3T3-L1 adipocytes. Mango peel (MPE) and mango seed (MSE) extracts significantly lowered PA-induced fat accumulation by reducing lipid droplet (LDs) and triacylglycerol (TAGs) content in adipocytes. We showed that MPE a…
Predicting soil and plant water status dynamic in olive orchards under different irrigation systems with Hydrus-2D: Model performance and scenario an…
2018
The paper analyzes the performance of Hydrus-2D model to simulate the dynamic of soil water contents and transpiration fluxes in an olive orchard in which two different irrigation systems were used in 2011 and 2012. The relationship between measured midday stem water potential, MSWP, and simulated relative transpiration (ratio between simulated actual and maximum crop transpiration), Ks, was also identified with the aim to use the model for crop water status predictions. Finally, a scenario analysis was carried out for irrigation management purposes, by considering the level of crop water stress achieved in the different phases of the vegetative growth. The results evidenced that active roo…
Being the Family Caregiver of a Patient With Dementia During the Coronavirus Disease 2019 Lockdown
2021
Background: Family caregivers of patients with dementia are at high risk of stress and burden, and quarantine due to the coronavirus disease 2019 (COVID-19) pandemic may have increased the risk of psychological disturbances in this population. The current study was carried out during the national lockdown declared in March 2020 by the Italian government as a containment measure of the first wave of the coronavirus pandemic and is the first nationwide survey on the impact of COVID-19 lockdown on the mental health of dementia informal caregivers.Methods: Eighty-seven dementia centers evenly distributed on the Italian territory enrolled 4,710 caregiver–patient pairs. Caregivers underwent a tel…
Detection of Water Stress in an Olive Orchard with Thermal Remote Sensing Imagery
2006
An investigation of the detection of water stress in non-homogeneous crop canopies such as orchards using high-spatial resolution remote sensing thermal imagery is presented. An airborne campaign was conducted with the Airborne Hyperspectral Scanner (AHS) acquiring imagery in 38 spectral bands in the 0.43–12.5 mm spectral range at 2.5 m spatial resolution. The AHS sensor was flown at 7:30, 9:30 and 12:30 GMT in 25 July 2004 over an olive orchard with three different water-deficit irrigation treatments to study the spatial and diurnal variability of temperature as a function of water stress. A total of 10 AHS bands located within the thermal-infrared region were assessed for the retrieval of…
Involvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis
2014
The synthetic cannabinoid WIN 55,212-2 is a potent cannabinoid receptor agonist with anticancer potential. Experiments were performed to determine the effects of WIN on proliferation, cell cycle distribution, and programmed cell death in human osteosarcoma MG63 and Saos-2 cells. Results show that WIN induced G2/M cell cycle arrest, which was associated with the induction of the main markers of ER stress (GRP78, CHOP and TRB3). In treated cells we also observed the conversion of the cytosolic form of the autophagosome marker LC3-I into LC3-II (the lipidated form located on the autophagosome membrane) and the enhanced incorporation of monodansylcadaverine and acridine orange, two markers of t…
WIN induces apoptotic cell death in human colon cancer cells through a block of autophagic flux dependent on PPARγ down-regulation.
2014
Cannabinoids have been reported to possess anti-tumorigenic activity in cancer models although their mechanism of action is not well understood. Here, we show that the synthetic cannabinoid WIN55,212-2 (WIN)-induced apoptosis in colon cancer cell lines is accompanied by endoplasmic reticulum stress induction. The formation of acidic vacuoles and the increase in LC3-II protein indicated the involvement of autophagic process which seemed to play a pro-survival role against the cytotoxic effects of the drug. However, the enhanced lysosomal membrane permeabilization (LMP) blocked the autophagic flux after the formation of autophagosomes as demonstrated by the accumulation of p62 and LC3, two ma…
Ethanol-Mediated Stress Promotes Autophagic Survival and Aggressiveness of Colon Cancer Cells via Activation of Nrf2/HO-1 Pathway
2019
Epidemiological studies suggest that chronic alcohol consumption is a lifestyle risk factor strongly associated with colorectal cancer development and progression. The aim of the present study was to examine the effect of ethanol (EtOH) on survival and progression of three different colon cancer cell lines (HCT116, HT29, and Caco-2). Our data showed that EtOH induces oxidative and endoplasmic reticulum (ER) stress, as demonstrated by reactive oxygen species (ROS) and ER stress markers Grp78, ATF6, PERK and, CHOP increase. Moreover, EtOH triggers an autophagic response which is accompanied by the upregulation of beclin, LC3-II, ATG7, and p62 proteins. The addition of the antioxidant N-acetyl…
Monitoring Yield and Fruit quality parameters in Open-Canopy Tree crops under Water Stress. Implications for ASTER
2007
Work on water stress detection at tree and orchard levels using a high-spatial airborne thermal sensor is presented, showing its connection with yield and some fruit quality indicators in olive and peach commercial orchards under different irrigation regimes. Two airborne campaigns were conducted with the Airborne Hyperspectral Scanner (AHS) over olive and peach orchards located in Córdoba, southern Spain. The AHS sensor was flown at three different times on 25 July 2004 and 16 July 2005, collecting 2 m spatial resolution imagery in 80 spectral bands in the 0.43– 12.5 μm spectral range. Thermal bands were assessed for the retrieval of land surface temperature using the split-window algorith…
Assessment of MODIS imagery to track light-use efficiency in a water-limited Mediterranean pine forest
2012
Abstract Daily values of gross primary production ( GPP ) derived from an eddy-covariance flux tower have been used to analyze the information content of the MODIS Photochemical Reflectance Index ( PRI ) on the light-use efficiency ( e ). The study has been conducted in a Mediterranean Pinus pinaster forest showing summer water stress. Advanced processing techniques have been used to analyze the effect of various external factors on e and PRI temporal variations. The intra-annual correlation between these two variables has been found to be mostly attributable to concurrent variations in sun and view zenith angles. The PRI has been normalized from these angular effects ( NPRI ), and its abil…