Search results for "ETHER-LIPIDS"

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Red blood cell plasmalogens and docosahexaenoic acid are independently reduced in primary open-angle glaucoma

2009

International audience; Among several theories involved in the pathogenesis of primary open-angle glaucoma (POAG), the vascular theory considers the disease to be a consequence of reduced ocular blood flow associated with red blood cell abnormalities. Red blood cell membrane structure and function are influenced by their phospholipid composition. We investigated whether specific lipid entities that may affect the membrane physiology, namely, polyunsaturated fatty acids (PUFAs) and plasmalogens, are modified in POAG and whether these potential variations are related to the stage of glaucoma. Blood samples were collected from 31 POAG patients and 10 healthy individuals. The stage of glaucoma …

Malegenetic structuresGlaucomaPathogenesischemistry.chemical_compound0302 clinical medicine[SDV.IDA]Life Sciences [q-bio]/Food engineeringETHER-LIPIDSERYTHROCITEchemistry.chemical_classificationAged 80 and over0303 health sciencesMiddle AgedSensory Systemsmedicine.anatomical_structureBiochemistryDocosahexaenoic acidDisease ProgressionFemalelipids (amino acids peptides and proteins)Glaucoma Open-AnglePolyunsaturated fatty acidmedicine.medical_specialtySpectrometry Mass Electrospray IonizationOpen angle glaucomaDocosahexaenoic AcidsPhospholipidBiology03 medical and health sciencesCellular and Molecular NeuroscienceInternal medicinemedicineHumans[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringPLASMALOGENSPRIMARY OPEN-ANGLE GLAUCOMA (POGA)030304 developmental biologyAgedErythrocyte MembraneBlood flowDOCOSAHEXAENOIC ACID (DHA)medicine.diseaseeye diseasesOphthalmologyRed blood cellEndocrinologychemistryCase-Control Studies030221 ophthalmology & optometrysense organsVisual FieldsChromatography Liquid
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