Search results for "EXPRESSION"
showing 10 items of 5168 documents
Dual mode of action of grape cane extracts against Botrytis cinerea
2019
International audience; Crude extracts of Vitis vinifera canes represent a natural source of stilbene compounds with well characterized antifungals properties. In our trials, exogenous application of a stilbene extract (SE) obtained from grape canes on grapevine leaves reduces the necrotic lesions caused by Botrytis cinerea. The SE showed to possess a direct antifungal activity by inhibiting the mycelium growth. The activation of some grapevine defense mechanism was also investigated. H2O2 production and activation of mitogen-activated protein kinase (MAPK) phosphorylation cascades as well as accumulation of stilbenoid phytoalexins were explored on grapevine cell suspension. Moreover, the t…
Heat shock factor 2 is a stress-responsive mediator of neuronal migration defects in models of fetal alcohol syndrome
2014
Fetal alcohol spectrum disorder (FASD) is a frequent cause of mental retardation. However, the molecular mechanisms underlying brain development defects induced by maternal alcohol consumption during pregnancy are unclear. We used normal and Hsf2-deficient mice and cell systems to uncover a pivotal role for heat shock factor 2 (HSF2) in radial neuronal migration defects in the cortex, a hallmark of fetal alcohol exposure. Upon fetal alcohol exposure, HSF2 is essential for the triggering of HSF1 activation, which is accompanied by distinctive post-translational modifications, and HSF2 steers the formation of atypical alcohol-specific HSF1–HSF2 heterocomplexes. This perturbs the in vivo bindi…
Cyclopropane Fatty Acid Synthase from Oenococcus oeni: Expression in Lactococcus lactis subsp. Cremoris and Biochemical Characterization
2015
Bacterial cyclopropane fatty acid synthases (CFA synthases) catalyze the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the double bond of a lipid chain, thereby forming a cyclopropane ring. CFAs contribute to resistance to acidity, dryness, and osmotic imbalance in many bacteria. This work describes the first biochemical characterization of a lactic acid bacterium CFA synthase. We have overexpressed Oenococcus oeni CFA synthase in E. coli in order to purify the enzyme. The optimum cyclopropanation activity was obtained at pH 5.6 and 35.8 °C. The high K(m) (AdoMet) value obtained (2.26 mM) demonstrates the low affinity of O. oeni enzyme toward the L. lactis subsp. cremo…
Blasphème et police administrative
2016
International audience
« Exprimer publiquement sa croyance: le débat sur le plainspeaking dans les années 1860-1870 »
2015
International audience; Dans le cadre de mes recherches sur la croyance, je m’intéresse à la question de l’expression publique dans le monde britannique à partir de 1860, et je souhaiterais examiner comment l’on passe d’un discours de l’individualité à un discours de la subjectivité et comment ces deux dimensions se nouent au politique entendu au sens large, s’y inscrivent et le redéfinissent en y inscrivant une culture du dissensus.
Vatermord im expressionistischen Drama
2010
Parole muette, récit burlesque : les expressions silencieuses aux XIXe-XXe siècles
2015
OS nat; National audience; Si l'on en croit une partie de la création et de la critique contemporaines, la littérature et les arts seraient d'essence silencieuse. Cet ouvrage propose une archéologie de cette esthétique silencieuse : comment une telle conception s'est-elle imposée ? Quels rapports entre la littérature et les arts, noués au coeur du XIXe siècle, ont-ils permis de faire de la parole muette la poésie par excellence et des expressions silencieuses la forme la plus achevée de l'art ? Quelles autres formes d'expressions, tout aussi silencieuses, ont-elles été mises au silence par cette définition esthétique essentialiste ? En explorant la poésie, le roman, la musique, la peinture,…
The impact of gender upon the appraisal of the self-relevance of others' angry expressions
2012
The impact of gender upon the appraisal of the self-relevance of others' angry expressions. The consortium of european research on emotion (CERE)
Cytosine methylation of tRNA-Asp by DNMT2 has a role in translation of proteins containing poly-Asp sequences
2015
AbstractThe Dnmt2 RNA methyltransferase catalyses the methylation of C38 in the anticodon loop of tRNA-Asp, but the molecular role of this methylation is unknown. Here, we report that mouse aspartyl-tRNA synthetase shows a four to fivefold preference for C38-methylated tRNA-Asp. Consistently, a 30% reduced charging level of tRNA-Asp was observed in Dnmt2 knockout (KO) murine embryonic fibroblast cells. Gene expression analysis with fluorescent reporter proteins fused to an N-terminal poly-Asp sequence showed that protein synthesis of poly-Asp-tagged reporter proteins was reduced in Dnmt2 KO cells as well. The same effect was observed with endogenous proteins containing poly-Asp sequences, i…
Mutual inductance for an explicitly finite number of turns
2011
Published version of an article published in Progress In Electromagnetics Research B, 28, 273-287. Also available from the publisher at http://www.jpier.org/pierb/pier.php?paper=10110103 Non coaxial mutual inductance calculations, based on a Bessel function formulation, are presented for coils modelled by an explicitly finite number of circular turns. The mutual inductance of two such turns can be expressed as an integral of a product of three Bessel functions and an exponential factor, and it is shown that the exponential factors can be analytically summed as a simple geometric progression, or other related sums. This allows the mutual inductance of two thin solenoids to be expressed as an…