Search results for "Echinococcu"
showing 10 items of 28 documents
Integration of animal health and public health surveillance sources to exhaustively inform the risk of zoonosis: An application to echinococcosis in …
2020
The analysis of zoonotic disease risk requires the consideration of both human and animal geo-referenced disease incidence data. Here we show an application of joint Bayesian analyses to the study of echinococcosis granulosus (EG) in the province of Rio Negro, Argentina. We focus on merging passive and active surveillance data sources of animal and human EG cases using joint Bayesian spatial and spatio-temporal models. While similar spatial clustering and temporal trending was apparent, there appears to be limited lagged dependence between animal and human outcomes. Beyond the data quality issues relating to missingness at different times, we were able to identify relations between dog and …
Fast-Growing Alveolar Echinococcosis Following Lung Transplantation
2020
International audience; Alveolar echinococcosis is a rare but life-threatening infection caused by the parasiteEchinococcus multilocularis. Its natural history is characterized by a slow parasitic growth over several years. Increased incidence and shorter development delay have been reported in immune-compromised patients. We report the reactivation of aborted lesions within 12 months of lung transplantation leading to a fast-growing aggressive hepatic lesion. Timely identification of alveolar echninococcosis allowed prompt albendazole treatment and radical surgery leading to a favorable outcome 42 months after transplantation. However, close clinical, serological and radiological monitorin…
Extracellular non-coding RNA signatures of the metacestode stage of Echinococcus multilocularis
2020
Extracellular RNAs (ex-RNAs) are secreted by cells through different means that may involve association with proteins, lipoproteins or extracellular vesicles (EV). In the context of parasitism, ex-RNAs represent new and exciting communication intermediaries with promising potential as novel biomarkers. In the last years, it was shown that helminth parasites secrete ex-RNAs, however, most work mainly focused on RNA secretion mediated by EV. Ex-RNA study is of special interest in those helminth infections that still lack biomarkers for early and/or follow-up diagnosis, such as echinococcosis, a neglected zoonotic disease caused by cestodes of the genus Echinococcus. In this work, we have char…
Cestode parasites release extracellular vesicles with microRNAs and immunodiagnostic protein cargo.
2017
Intercellular communication is crucial in multiple aspects of cell biology. This interaction can be mediated by several mechanisms including extracellular vesicle (EV) transfer. EV secretion by parasites has been reported in protozoans, trematodes and nematodes. Here we report that this mechanism is present in three different species of cestodes, Taenia crassiceps, Mesocestoides corti and Echinococcus multilocularis. To confirm this we determined, in vitro, the presence of EVs in culture supernatants by transmission electron microscopy. Interestingly, while T. crassiceps and M. corti metacestodes secrete membranous structures into the culture media, similar vesicles were observed in the int…
Phenotypic analysis of peripheral lymphocyte subpopulations in hydatid patients.
1999
Peripheral T-lymphocytes were analyzed in three groups of people: (1) individuals with current liver hydatid disease (hydatid patients, n = 20), (2) persons who had undergone surgical cyst removal at least 2 years previously (recovered patients, n = 9), and (3) a control group of healthy volunteers (uninfected controls, n = 13). Group 1 was subdivided according to cyst status, relapse of disease, and the presence or absence of symptoms. Percentages of lymphocytes expressing CD3, CD4, CD8, CD56, CD25, CD45RA, CD45RO, and HLA-DR were determined. Symptomatic patients had proportionally fewer CD3+ CD8 + lymphocytes than the control group (P=0.038). Hydatid patients with active cysts had proport…
Multimodality imaging in cardiac echinococcosis for diagnosis and follow-up of an untreatable cyst
2016
Human cysticercosis and larval tropism of Taenia asiatica
2000
Taenia solium, T. saginata and the recently discovered T. asiatica1xTaiwan Taenia and taeniasis. Fan, P.C. Parasitol. Today. 1988; 4: 86–88Abstract | Full Text PDF | PubMed | Scopus (61)See all References, 2xMorphologic descriptions of Taenia asiatica sp. n.. Eom, K.S. and Rim, H.J. Korean J. Parasitol. 1993; 31: 1–6Crossref | PubMedSee all References, 3xMorphological description of Taenia saginata asiatica (Cyclophyllidea: Taeniidae) from man in Asia. Fan, P.C. et al. J. Helminthol. 1995; 69: 299–303Crossref | PubMed | Scopus (44)See all References, are species of taeniid cestodes whose adult stages are known to infect humans. Less clear is whether the eggs of T. asiatica also infect human…
Cystic hydatidosis: a rare case of spine localization.
2011
Les nuées dynamiques floues appliquées au développement dune typologie paysagère
2007
International audience; Un programme d'épidémiosurveillance actuellement en cours vise à évaluer la présence du parasite Echinococcus multilocularis en France. Contrairement aux hypothèses écologiques initiales, le parasite et ses hôtes ne semblent pas privilégier certains modes d'occupation du sol plus que d'autres. L'objectif de ce travail consiste à identifier dans un premier temps les contextes paysagers au sein desquels la présence parasitaire est confirmée puis, dans un second temps, à mettre en évidence un gradient dans les prévalences spécifiques à chacun de ces contextes. Les nuées dynamiques floues ont permis d'optimiser et de critiquer la typologie paysagère établie. La hiérarchi…