Search results for "Economics."

showing 10 items of 14210 documents

Assessing statistical significance in multivariable genome wide association analysis

2016

Motivation: Although Genome Wide Association Studies (GWAS) genotype a very large number of single nucleotide polymorphisms (SNPs), the data are often analyzed one SNP at a time. The low predictive power of single SNPs, coupled with the high significance threshold needed to correct for multiple testing, greatly decreases the power of GWAS. Results: We propose a procedure in which all the SNPs are analyzed in a multiple generalized linear model, and we show its use for extremely high-dimensional datasets. Our method yields P-values for assessing significance of single SNPs or groups of SNPs while controlling for all other SNPs and the family wise error rate (FWER). Thus, our method tests whe…

0301 basic medicineStatistics and Probability1303 BiochemistryGenotypeOperations researchLibrary sciencePolymorphism Single NucleotideBiochemistryGerman03 medical and health sciences10007 Department of EconomicsPolitical scienceGenome-Wide Association Analysis1312 Molecular Biology1706 Computer Science ApplicationsCluster AnalysisHumansComputer Simulation2613 Statistics and ProbabilityMolecular BiologyEuropean researchGenetics and Population AnalysisComputational BiologyReproducibility of ResultsOriginal Paperslanguage.human_languageComputer Science Applications330 EconomicsComputational MathematicsPhenotype030104 developmental biologyComputational Theory and MathematicsLinear Modelslanguage2605 Computational MathematicsGenome-Wide Association Study1703 Computational Theory and Mathematics
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Collapsibility of the internal jugular veins in the lateral decubitus body position: A potential protective role of the cerebral venous outflow again…

2019

Recent research has revealed that patients with neurodegenerative disease sleep longer in the supine position, while healthy controls prefer sleeping in the lateral decubitus position. Thus, sleeping in the lateral position seems to be protective against neurodegeneration. It has also been suggested that a protective role of this body position could be associated with better cerebral venous drainage in this body position, which results in more active glymphatic system of the brain (the system responsible for clearance of the cerebral tissue from waste products, e.g. amyloid-β). Since no published evidence exists regarding venous outflow from the cranial cavity in the lateral decubitus posit…

0301 basic medicineSupine positionModels NeurologicalPostureBlood PressurePilot ProjectsLateral decubitus positionSitting03 medical and health sciencesHabits0302 clinical medicineAlzheimer DiseaseReference Valuesmental disordersCranial cavitymedicineLateral Decubitus PositionSupine PositionHumansNeurodegenerationInternal jugular veinhealth care economics and organizationsUltrasonographyRight Lateral Decubitus PositionAquaporin 4business.industryNeurodegenerationHemodynamicsGeneral MedicineAnatomyAlzheimer's diseasemedicine.diseaseCerebral Veins030104 developmental biologymedicine.anatomical_structureCerebrovascular CirculationPulsatile FlowNerve Degenerationcardiovascular systemInternal jugular veinGlymphatic systemJugular VeinsbusinessSleepGlymphatic System030217 neurology & neurosurgeryBlood Flow VelocityMedical hypotheses
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Impact of Very Hot Drink Consumption Habits, Age, and Sex, on Taste Sensitivity

2021

The temperature range for consuming hot drinks includes temperatures that can damage cells on the tongue. We hypothesized that the consumption of very hot drinks can lead to a decrease in the ability to perceive low concentrations of tastants. We evaluated the ability to perceive low concentrations of five prototypical sapid compounds in 42 women and 40 men aged 18–65. A questionnaire made it possible to collect the usual frequencies (number of unit/day) and consumption temperature levels (medium hot/very hot) for four very common hot drinks (coffee, tea, herbal infusions, and hot chocolate). Our results showed that subjects who consumed very hot drinks (versus medium hot) were less sensiti…

0301 basic medicineTasteHealth (social science)Plant ScienceUmamiTP1-1185Age and sexHealth Professions (miscellaneous)MicrobiologyArticleT@sty03 medical and health sciences0302 clinical medicinegenderMedicineFood sciencehot drinkVolume concentrationConsumption (economics)030109 nutrition & dieteticsbusiness.industryChemical technologyfood and beveragestemperatureSweet tastetaste sensitivity[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitologyage030220 oncology & carcinogenesisbusiness[SDV.AEN]Life Sciences [q-bio]/Food and NutritionFood ScienceFoods
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Hsp60 quantification in human gastric mucosa shows differences between pathologies with various degrees of proliferation and malignancy grade

2021

Background: Stomach diseases are an important sector of gastroenterology, including proliferative benign

0301 basic medicineTechnologyPathologymedicine.medical_specialtyQH301-705.5QC1-999intestinal metaplasia03 medical and health sciences0302 clinical medicinechaperone systemMetaplasiamedicineGastric mucosaGeneral Materials ScienceBiology (General)QD1-999Instrumentationhealth care economics and organizationsFluid Flow and Transfer Processesbusiness.industryChaperone system Gastric carcinogenesis Gastric dysplasia Gastritis Hsp60 Intestinal metaplasiaSettore BIO/16 - Anatomia UmanaTPhysicsProcess Chemistry and TechnologyStomachdigestive oral and skin physiologygastritisGeneral EngineeringIntestinal metaplasiagastric dysplasiaEngineering (General). Civil engineering (General)Hsp60medicine.diseasedigestive system diseasesComputer Science ApplicationsChemistryGastric Dysplasia030104 developmental biologymedicine.anatomical_structureHyperplastic PolypDysplasia030220 oncology & carcinogenesisgastric carcinogenesisTA1-2040medicine.symptomGastritisbusiness
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Pursuing softer urban mobility behaviors through game-based apps

2020

Cities are currently engaged through their urban policies in pushing people towards less environmentally impacting mobility modalities: therefore, cycling and walking are strongly promoted, especially by means of new and wider limited traffic and no-cars zones. In this paper, the effectiveness of the new smartphones and apps-based technologies in modifying the mobility behaviors of citizens towards more sustainable choices has been investigated. Specifically, the potential of a smartphone app, directly involving citizens by means of a game rewarding the most sustainable trips, has been tested on a university commuters' group. These latter, starting from their current mobility situation, wer…

0301 basic medicineUrban energy consumptionInformation sciencePsychological interventionEnvironmental pollution7. Clean energyArticleInformation scienceEnvironmental pollutionEnvironmental science03 medical and health sciences0302 clinical medicineEnvironmental analysi11. SustainabilityClimate changelcsh:Social sciences (General)lcsh:Science (General)Environmental analysisGame-based appMultidisciplinaryModalitiesSettore ING-IND/11 - Fisica Tecnica AmbientaleUrban policyEnvironmental economicsCommuter030104 developmental biology13. Climate actionClimate policySweet mobilitySmartphone appAir qualityTRIPS architectureGame basedlcsh:H1-99Smartphone030217 neurology & neurosurgeryCommuterslcsh:Q1-390Heliyon
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Creation of a brand model through SEM to predict users' loyalty and recommendations regarding a public sports service.

2021

Brand perception is a key element in achieving business success: how a brand is perceived by current and potential users determines what they think and their disposition towards the brand. The users' perception also determines whether they will perceive the sports service as offering a greater quality or value than other services, whether they will be more loyal, or whether they will recommend the service. This paper analyses the brand perception of users of a public sports service, creating a model of structural equations that analyses how credibility and trust influence a user's congruence with the brand and the generation of positive attitudes towards the brand and how these variables in…

0301 basic medicineValue (ethics)Science (General)media_common.quotation_subjectWord of mouthQ1-39003 medical and health sciencesLoyalty0302 clinical medicineCongruence (geometry)Word-of-mouthPerceptionLoyaltyCredibilityQuality (business)media_commonH1-99MarketingMultidisciplinaryBrand perceptionAdvertisingSocial sciences (General)030104 developmental biologyService (economics)Psychology030217 neurology & neurosurgeryResearch ArticleSports servicesHeliyon
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Relationship between olive oil consumption and ankle-brachial pressure index in a population at high cardiovascular risk.

2020

[Background and aims]: The aim of this study was to ascertain the association between the consumption of different categories of edible olive oils (virgin olive oils and olive oil) and olive pomace oil and ankle-brachial pressure index (ABI) in participants in the PREDIMED-Plus study, a trial of lifestyle modification for weight and cardiovascular event reduction in individuals with overweight/obesity harboring the metabolic syndrome.

0301 basic medicineVirgin olive oils*Olive oil*Peripheral artery diseasePopulation*Olive pomace oil030204 cardiovascular system & hematologyOverweightToxicology03 medical and health sciences0302 clinical medicine*Virgin olive oils*Ankle-brachial pressure indexRisk Factorsmedicine*PREDIMED-Plus trialOlive pomace oilHumansPlant OilseducationOlive OilConsumption (economics)education.field_of_studyPeripheral artery diseaseMalalties cardiovascularsbusiness.industryPomacePREDIMED-Plus trialOdds ratiomedicine.diseaseObesityConfidence interval3. Good healthOli d'oliva030104 developmental biologyCross-Sectional StudiesCardiovascular DiseasesHeart Disease Risk FactorsAnkle-brachial pressure indexMetabolic syndromemedicine.symptomAnkleCardiology and Cardiovascular Medicinebusiness
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Fractional hereditariness of lipid membranes: Instabilities and linearized evolution

2016

In this work lipid ordering phase changes arising in planar membrane bilayers is investigated both accounting for elas- ticity alone and for effective viscoelastic response of such assemblies. The mechanical response of such membranes is studied by minimizing the Gibbs free energy which penalizes perturbations of the changes of areal stretch and their gradients only [1]. As material instabilities arise whenever areal stretches characterizing homogeneous configurations lie inside the spinoidal zone of the free energy density, bifurcations from such configurations are shown to occur as oscillatory perturbations of the in-plane displacement. Experimental observations [2] show a power-law in-pl…

0301 basic medicineViscoelastic lipid membranePhase transitionMembrane Fluidity0206 medical engineeringLipid BilayersBiomedical EngineeringSeparation of variablesFOS: Physical sciences02 engineering and technologyviscoelastic lipid membranesCondensed Matter - Soft Condensed Matterfractional hereditary lipid membranesViscoelasticityFractional hereditary lipid membraneMaterial instabilitieBiomaterials03 medical and health sciencessymbols.namesakeFractional hereditary lipid membranes; Material instabilities; Phase transitions; Viscoelastic lipid membranes; Biomaterials; Biomedical Engineering; Mechanics of MaterialsVariational principleElasticity (economics)Phase transitionMembranesChemistryOscillationTime evolutionBiomaterial020601 biomedical engineeringElasticityGibbs free energyphase transitions030104 developmental biologyClassical mechanicsModels ChemicalMechanics of MaterialssymbolsSoft Condensed Matter (cond-mat.soft)material instabilitiesSettore ICAR/08 - Scienza Delle Costruzionifractional hereditary lipid membranes viscoelastic lipid membranes phase transitions material instabilities
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Changes in the international wine market competitiveness

2017

This study offers a contribution to understanding the complexity of the international wine trade analysing the specialisation patterns of 14 among the most important wine world actors in the period 2007–2016, in order to verify if the patterns of comparative advantages for the trade of this countries have experienced significant changes. Using the Lafay index, as a comparative advantage measure, our results reveal deep changes in the global wine market exchange. Our result constitutes a base element for the future development of the competitive scenario and provides some both theoretical and practical implications. In the baseline projection, the maintenance of the competitive position is…

0301 basic medicineWineWine trade.030109 nutrition & dieteticsIndex (economics)Information Systems and ManagementComparative advantageTrade specialisationManagement Science and Operations Research03 medical and health sciencesOrder (exchange)Settore AGR/01 - Economia Ed Estimo RuralePosition (finance)BusinessElement (criminal law)Business and International ManagementBaseline (configuration management)Practical implicationsIndustrial organizationComparative advantageLafay indexInternational Journal of Globalisation and Small Business
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Stability of stationary solutions in models of the Calvin cycle

2017

Abstract In this paper results are obtained concerning the number of positive stationary solutions in simple models of the Calvin cycle of photosynthesis and the stability of these solutions. It is proved that there are open sets of parameters in the model of Zhu et al. (2009) for which there exist two positive stationary solutions. There are never more than two isolated positive stationary solutions but under certain explicit special conditions on the parameters there is a whole continuum of positive stationary solutions. It is also shown that in the set of parameter values for which two isolated positive stationary solutions exist there is an open subset where one of the solutions is asym…

0301 basic medicineWork (thermodynamics)Applied Mathematics010102 general mathematicsGeneral EngineeringOpen setGeneral MedicineMathematical proof01 natural sciencesStability (probability)03 medical and health sciencesComputational Mathematics030104 developmental biologySimple (abstract algebra)Stability theoryApplied mathematicsContinuum (set theory)0101 mathematicsGeneral Economics Econometrics and FinanceAnalysisBifurcationMathematicsNonlinear Analysis: Real World Applications
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