Search results for "Editoria"
showing 10 items of 453 documents
Oxidant antioxidants and adaptive responses to exercise.
2015
The extensive damage produced by unaccustomed (acute) exercise and the health benefits of regular physical activity are well-known phenomena as well as the role played in them by reactive oxygen species (ROS). The present issue reports some interesting studies showing that the Janus faced effects of exercise-induced ROS in skeletal muscle. Most studies dealing with ROS contribution to acute exercise-induced tissue damage determine the levels of markers of oxidative damage to specific substances but they do not take into account total redox status of an individual before and after exercise. In their research article D. Stagos et al. used markers measuring plasma static (sORP) and capacity (c…
Animal Models of Stress - Current Knowledge and Potential Directions
2021
Finding new therapies and new antidepressant agents is of high clinical priority given that many cases of depressive disorder do not respond to conventional monoaminergic antidepressants such as selective serotonin reuptake inhibitors, tricyclic antidepressants, and monoamine oxidase inhibitors The authors demonstrated that electroacupuncture and fluoxetine, a second-generation antidepressant categorized as a selective serotonin reuptake inhibitor (Perez-Caballero et al , 2014), regulate the expression of key proteins in the calmodulin kinase (CAMK) signaling pathway, which are related to depression in the hippocampi of rats (Takemoto-Kimura et al , 2017;Xie et al , 2019) In a paper on “Sho…
Adverse Reactions to Anticancer Drugs in the Oral Cavity
2018
The development, testing, and adoption into clinical practice of anticancer medications have revolutionized cancer care over the past decades. A better understanding of the biology of cancer has translated into development of novel systemic agents, as well a more effective use of older chemotherapy agents. As a consequence, cancer mortality continues to decrease. However, greater cure and disease control rates come at a price of an increased risk of adverse effects, which often affects the mouth and related structures including the oral mucosa, salivary glands, jawbones, and cranial nerves. Oral mucositis, hyposalivation, dysgeusia, and osteonecrosis of the jaw (ONJ) are some examples of th…
Biomaterials and bioactive molecules to drive differentiation in striated muscle tissue engineering
2015
International audience; The generation of engineered tissues and organs has entered into the clinical practice in response to the chronic lack of organ donors. In particular, for the skeletal and cardiac muscles the translational potential of tissue engineering approaches has clearly been shown, even though the construction of these tissues lags behind others given the hierarchical, highly organized architecture of striated muscles. Failure of the cardiac tissue leads to cardiovascular diseases, which are the leading cause of death in the developed world (Di Felice et al., 2014). On the other hand, there are many clinical cases where the loss of skeletal muscle due to a traumatic injury, an…
Predictors of oncological outcomes in T1G3 patients treated with BCG who undergo radical cystectomy
2018
PURPOSE: To evaluate the oncological impact of postponing radical cystectomy (RC) to allow further conservative therapies prior to progression in a large multicentre retrospective cohort of T1-HG/G3 patients initially treated with BCG. METHODS: According to the time of RC, the population was divided into 3 groups: patients who did not progress to muscle-invasive disease, patients who progressed before radical cystectomy and patients who experienced progression at the time of radical cystectomy. Clinical and pathological outcomes were compared across the three groups. RESULTS: Of 2451 patients, 509 (20.8%) underwent RC. Patients with tumors > 3 cm or with CIS had earlier cystectomies (HR = 1…
Dopamine Interaction with other Neurotransmitter Systems: Relevance in the Pathophysiology and Treatment of CNS Disorders
2010
The “Journal of Functional Morphology and Kinesiology” Journal Club Series: Highlights of Recent Papers in Pediatric Exercise
2019
We are glad to introduce the ninth Journal Club. This edition is focused on several relevant studies published in the last years in the field of Pediatric Exercise, chosen by our Editorial Board members and their colleagues. We hope to stimulate your curiosity in this field and to share with you the passion for the sport as seen also from the scientific point of view. The Editorial Board members wish you an inspiring lecture.
Noninvasive Testing Using Magnetic Resonance Imaging Techniques as Outcomes in Nonalcoholic Steatohepatitis Clinical Trials: How Full Is the Glass?
2020
El valencianisme lingüístic de Nicolau Primitiu Gómez Serrano
2012
Aquest article constitueix un estudi de les activitats més rellevants i la posició ideològica de Nicolau Primitiu Gómez Serrano al voltant del català de València: fixació de la toponímia del País Valencià, defensa i difusió de les Normes de Castelló, reivindicació de l’ús del valencià a l’escola i del seu ensenyament, promoció del Diccionari Català-Valencià-Balear d’Alcover-Moll, creació de plataformes editorials i teories sobre l’origen i el nom de la llengua dels valencians.
Editorial decisions: highlighting the role of systematic reviews
2018
En 2014, el doctor Gerard Urrútia del Centro Cochrane Iberoamericano - Institut d'Investigació Biomèdica Sant Pau, escribió unas líneas editoriales para la Revista Española de Nutrición Humana y Dietética1 en las que ponía en valor la necesidad de "incrementar el rigor científico tanto en la producción de estudios científicos, que proporcionen las bases para una toma de decisiones bien fundamentada, como en su divulgación mediante publicaciones científicas de calidad" en el ámbito de la nutrición y la dietética. Asimismo vaticinaba que "cabría esperar, por una parte, un creciente interés en la producción de revisiones sistemáticas por parte de profesionales de nuestro medio, también entre d…