Search results for "Enos"

showing 10 items of 1576 documents

Endovascular Treatment with Drug-Eluting Balloon for Severe Subclavian Artery Stenosis Involving the Origin of the Vertebral Artery

2020

The first line approach for subclavian steal syndrome is PTA-stenting of subclavian artery. When the ipsilateral vertebral artery origin is involved or in closed proximity of the atherosclerotic lesion in the subclavian artery PTA-stenting is at risk of ipsilateral vertebral artery coverage. Herein we report our experience with DEB to address lesions involving the subclavian artery and the origin of the ipsilateral vertebral artery. From January 2017 to February 2019, patients presenting subclavian artery lesion involving the origin of the ipsilateral vertebral artery and treated using primary DEB, were included. Three patients, with left subclavian steal syndrome, were identified. The peri…

body regionssurgical procedures operativesteal syndromesubclavian artery stenosiscardiovascular systemballoon angioplastyArticlescardiovascular diseasesdrug eluting balloonSettore MED/22 - Chirurgia Vascolare
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Anti-resorptive treatment in osteoporosis and their deleterious effects on maxillary bone metabolism in clinical dentistry

2017

Bisphosphonates (BPs) and other antiresorptive agents such as denosumab are widely prescribed for the treatment of osteoporosis and are also used in patients with multiple myeloma and metastatic breast or prostate cancer for avoiding bone reabsorption and fractures that result in increased morbidity–mortality among such individuals. Osteonecrosis of the jaws is an important complication of exposure to BPs or other antiresorptive agents, and although its prevalence is low, it can pose management problems. The definition, diagnosis, and classification of osteonecrosis have evolved since Marx reported the first cases in 2003. The present chapter offers a review and update on the existing diagn…

business.industrymedicine.medical_treatmentOsteoporosisDentistryBisphosphonatemedicine.diseaseBone resorptionBone remodelingProstate cancerDenosumabmedicinebusinessComplicationMultiple myelomamedicine.drug
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Modular Breath Analyzer (MBA): Introduction of a Breath Analyzer Platform Based on an Innovative and Unique, Modular eNose Concept for Breath Diagnos…

2021

Exhaled breath analysis for early disease detection may provide a convenient method for painless and non-invasive diagnosis. In this work, a novel, compact and easy-to-use breath analyzer platform with a modular sensing chamber and direct breath sampling unit is presented. The developed analyzer system comprises a compact, low volume, temperature-controlled sensing chamber in three modules that can host any type of resistive gas sensor arrays. Furthermore, in this study three modular breath analyzers are explicitly tested for reproducibility in a real-life breath analysis experiment with several calibration transfer (CT) techniques using transfer samples from the experiment. The experiment …

calibration transferComputer scienceRespiratory SystemPharmaceutical ScienceOrganic chemistrycorrelation alignment01 natural scienceseNoseAnalytical Chemistry0302 clinical medicineQD241-441DDC 570 / Life sciencesDrug Discoverybreath analysisSensortechnikdigestive oral and skin physiologyAtemgasanalyseMischoxideExhalationChemistry (miscellaneous)piecewise direct standardization030220 oncology & carcinogenesisElektronische NaseCalibrationMolecular MedicineMOX sensorsSpectrum analyzerAdolescentlow sensing chamber volumeReal-time computingstandard samplesbreath samplingArticleElectronic nose03 medical and health sciencesddc:570Breath testsCalibrationHumansddc:610Physical and Theoretical ChemistryReproducibilitybusiness.industry010401 analytical chemistryBreath samplingpattern recognitionBreath diagnosticsAtemluftModular design0104 chemical sciencesBreath analyzerBreath gas analysisbusinessBiosensing techniquesDDC 610 / Medicine & healthBiomarkersMolecules
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Ezetimibe, cardiovascular risk and atherogenic dyslipidaemia.

2010

Ezetimibe is a selective cholesterol absorption inhibitor with an excellent side-effect profile, able to reduce low-density lipoprotein (LDL) cholesterol by 15-25% from baseline in monotherapy and on top of statins and fibrates. Yet, it seems that ezetimibe produces quantitative rather than qualitative changes in LDL, with small net effects on atherogenic dyslipidaemia. This is supported by findings from the Ezetimibe and Simvastatin in Hypercholesterolemia Enhances Atherosclerosis Regression (ENHANCE) study on atherosclerosis progression, where the addition of ezetimibe to simvastatin in patients with heterozygous familial hypercholesterolaemia did not affect the mean change in carotid int…

cardiovascular riskAortic valvemedicine.medical_specialtydyslipidaemiamedicine.drug_classezetimibe cardiovascular risk atherosclerosis dyslipidaemiachemistry.chemical_compoundEzetimibeInternal medicineClinical endpointMedicineCholesterol absorption inhibitorcardiovascular diseasesReview Paperbusiness.industryCholesterolnutritional and metabolic diseasesGeneral Medicinemedicine.diseaseStenosismedicine.anatomical_structureEndocrinologychemistrySimvastatinCardiologylipids (amino acids peptides and proteins)atherosclerosisbusinessezetimibeLipoproteinmedicine.drug
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Asymptomatic carotid lesions and aging: role of hypertension and other traditional and emerging risk factors

2005

ASYMPTOMATIC CAROTID LESIONS AND AGING: ROLE OF HYPERTENSION AND OTHER TRADITIONAL AND EMERGING RISK FACTORS BACKGROUND: We evaluated the prevalence of intima-media thickening (IMT) and asymptomatic carotid plaque (ACP) in a group of subjects with or without traditional and/or emerging risk factors (RF). METHODS: There were 631 subjects (313 male and 318 female) aged between 19 and 97 years, asymptomatic for cerebro- and cardiovascular diseases. The following measurements were used: anamnesis, physical examination, height and sitting blood pressure. Biochemistry variables were also considered: total cholesterol, HDL-C, LDL-C, triglycerides, fibrinogen, high sensitive C-reactive protein, IgG…

carotid stenosiatherosclerosihypertensionSettore MED/09 - Medicina Internarisk factorsSettore MED/11 - Malattie Dell'Apparato Cardiovascolare
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Carotid endarterectomy versus stenting in patients with contralateral carotid artery occlusion

2012

Aim. The aim of this prospective study was to compare outcomes after CEA and CAS in patients with contralateral carotid artery occlusion. Methods. Between 2004 and 2009, 527 consecutive patients underwent CEA (N.=281) or CAS (N.=246) for severe stenosis of internal carotid artery (ICA). Of them, 85 (16.1%) were identified with contralateral carotid artery occlusion. CEA was performed in 31(36.4%) patients with contralateral ICA occlusion, and 15 (48.4%) were symptomatic. Intraoperative shunts were placed in 12% versus 41.9% (P<0.001) patients with patent (N.=250) or occluded contralateral ICA (N.=31). Fifty-four (63.5%) patients with contralateral ICA occlusion underwent CAS with distal pro…

carotid stenosiendarterectomystentSettore MED/22 - Chirurgia Vascolare
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Crop type and altitude are the main drivers of species composition of arable weed vegetation in Tajikistan

2015

Summary The influence of broad-scale environmental factors on the species composition of segetal weed communities in Tajikistan was investigated. The research was conducted throughout the country, analysing plots of root crops as well as cereals from all phytogeographical regions of Tajikistan, with the exception of the eastern Pamir. The study was based on 440 phytosociological relevees sampled between 2009 and 2013 and analysed using direct and indirect ordinations. A set of environmental variables was obtained for each plot: altitude, mean annual precipitation, mean annual temperature, pH, crop type, longitude, latitude and date of sampling (seasonality). Crop type was the major factor d…

cerealsCommunity structurePlant ScienceVegetationseasonal dynamicSeasonalitysegetal communitiesmedicine.diseaseLatitudeAltitudeGeographyAgronomyCanonical correspondence analysismedicineagrocoenosesArable landroot cropsWeedCCAAgronomy and Crop ScienceEcology Evolution Behavior and SystematicsaltitudeWeed Research : the official Journal of the European Weed Research Society
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Retracted Article: Differential detection and quantification of cyclic AMP and other adenosine phosphates in live cells

2017

A new naphthol-based rhodamine derivative (NpRD) has been developed for the selective and differential detection of adenosine 3′,5′-cyclic monophosphate (cAMP) and adenosine phosphates (APs) (ATP, ADP, and AMP) from other nucleotides. The simple detection and quantification of cAMP in human blood cells and in other samples based on the ‘turn on’ fluorescence properties of this chemosensor through colorimetry or fluorometry makes it unique for probable application in high throughput screening.

chemistry.chemical_classification010405 organic chemistryCell growthHigh-throughput screeningMetals and AlloysGeneral Chemistry010402 general chemistry01 natural sciencesFluorescenceAdenosineCatalysisColorimetry (chemical method)Fluorescence spectroscopy0104 chemical sciencesSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryBiochemistryCell cultureMaterials ChemistryCeramics and CompositesmedicineNucleotidemedicine.drugChemical Communications
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Evidence for essential primary amino groups in a bacterial coupling factor F1ATPase.

1980

Abstract We have found that the binding of pyridoxal-5′-phosphate to 6 primary amino groups leads to the inactivation of the enzyme. A preferential reaction of pyridoxal-5′-phosphate with the α-subunits of this enzyme can be demonstrated. The reactivity of the amino groups is influenced by various effectors. In the presence of ATP the inhibition of the ATPase activity is noncompetitive.

chemistry.chemical_classificationAdenosine TriphosphatasesPrimary (chemistry)Binding SitesChemistryStereochemistryEffectorCell MembraneBiophysicsCell BiologyBiochemistryMicrococcusCoupling (electronics)Structure-Activity RelationshipEnzymeBiochemistrySolubilityPyridoxal PhosphateAtpase activityReactivity (chemistry)Amino AcidsMolecular BiologyBiochemical and biophysical research communications
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Identification and structural characterization of O-beta-ribosyl-(1"----2')-adenosine-5"-phosphate in yeast methionine initiator tRNA.

1990

We report in this paper on the complete structure determination of the modified nucleotide A*, now called Ar(p), that was previously identified in yeast methionine initiator tRNA as an isomeric form of O-ribosyl-adenosine bearing an additional phosphoryl-monoester group on its ribose2 moiety. By using the chemical procedure of periodate oxidation and subsequent beta-elimination with cyclohexylamine on mono- and dinucleotides containing Ar(p), we characterized the location of the phosphate group on the C-5" of the ribose2 moiety, and the linkage between the two riboses as a (1"----2')-glycosidic bond. Since the structural difference between phosphatase treated Ar(p) and authentic O-alpha-rib…

chemistry.chemical_classificationAdenosine monophosphateMethionineRNA Transfer MetStereochemistryChemical structurePhosphataseCyclohexylamineSaccharomyces cerevisiaeBiologyAdenosine Monophosphatechemistry.chemical_compoundchemistryBiochemistryTransfer RNAGeneticsMoietyNucleotideIndicators and ReagentsOxidation-ReductionChromatography High Pressure LiquidNucleic acids research
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