Search results for "Ephedrine"
showing 4 items of 34 documents
Chiral separation of ephedrines by liquid chromatography using β-cyclodextrins
2001
β-cyclodextrins (β-CDs) have been evaluated as chiral recognition agents for the enantioseparation of ephedrines by liquid chromatography (LC). The compounds tested were norephedrine, ephedrine, pseudoephedrine, N-methylephedrine and N-methylpseuoephedrine. Two possibilities have been investigated, the employment of a chiral stationary phase consisting of immobilized β-cyclodextrin, and the addition of the chiral selector to the mobile phase. In the latter approach the following chiral agents have been assayed, native β-cyclodextrin (β-CD), methyl-β-cyclodextrin (M-β-CD), carboxyethyl-β-cyclodextrin (CE-β-CD), carboxymethyl-β-cyclodextrin (CM-β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD)…
Modifying the reactivity of copper (II) by its encapsulation into polydimethylsiloxane: A selective sensor for ephedrine-like compounds
2018
This paper demonstrates that the reactivity of copper (II) can be modified through its entrappment in a polymeric matrix of polydimethylsiloxane (PDMS), which makes possible the reaction into the support instead of in solution. Amino-containing compounds such as amino acids, proteins and sugars, which react with Cu (II) in solution, do not react inside the polymer. As a prove of concept, a highly specific Cu (II) PDMS-based sensor for ephedrines has been developed in this work. When the sensors are put into contact with solutions of these drugs under basic conditions, a change in their color from pale green to purple is observed. This change enables the visual identification of ephedrine (E…
A cocrystal of two Mo(VI) complexes bearing different diastereomers of the 2,4-di-tert-butyl-6-{[(1-oxido-1-phenylpropan-2-yl)(methyl)amino]methyl}ph…
2013
The title cocrystal contains two chiral conformational diastereomers, viz. (1S,2R,RN)- and (1S,2R,SN)-, of [2,4-ditert-butyl-6-{[(1-oxido-1-phenylpropan-2-yl)(methyl)amino]- methyl}phenolato](methanol)-cis-dioxidomolybdenum(VI), [Mo(C25H35NO2)O2(CH3OH)], representing the first example of a structurally characterized molybdenum complex with enantiomerically pure ephedrine derivative ligands. The MoVI cations exhibit differently distorted octahedral coordination environments, with two oxide ligands positioned cis to each other. The remainder of the coordination comprises phenoxide, alkoxide and methanol O atoms, with an amine N atom completing the octahedron. The distinct complexes are linked…
1539 Length of Hospital Stay in Children with Acute Viral Pneumonia Treated with Corticosteroids, A Retrospective Study
2012
Background Corticosteroids with or without ephedrine may have positive effects in viral pneumonia treatment accelerating the time to resolution of symtpoms but the evidence is not strong enough to make specific recommandations. Objectives Evaluating the hospital length stay of the children with viral pneumonia treated with corticosteroids, single or in combination with ephedrine. Material and Methods The retrospective study included pacients admitted in our clinic with viral pneumonia during 2011. From 167 cases, 78 cases were selected according to specific criteria: patients having received cortisone (hydrocortisone hemisuccinate and/or fluticasone propionate) associated or not with ephedr…