Search results for "Epos"

showing 10 items of 1649 documents

The ISTH bleeding assessment tool as predictor of bleeding events in inherited platelet disorders: Communication from the ISTH SSC Subcommittee on Pl…

2021

Background: The ISTH Bleeding Assessment Tool (ISTH-BAT) has been validated for clinical screening of suspected von Willebrand disease (VWD) and for bleeding prediction. Recently it has been validated for subjects with inherited platelet disorders (IPD) (BAT-VAL study). Objectives: To determine whether the ISTH-BAT bleeding score (BS) predicts subsequent bleeding events requiring treatment in IPD patients. Methods: Patients with IPD, type 1 VWD (VWD-1) and age- and sex-matched healthy controls enrolled in the BAT-VAL study were prospectively followed-up for 2 years and bleeding episodes requiring treatment were recorded. Results: Of the 1098 subjects initially enrolled, 955 were followed-up…

medicine.medical_specialtyanimal structuresmild&#8208Platelet Function TestsPlatelet disorderinherited platelet disorderHemorrhage030204 cardiovascular system & hematologyHemorrhage/diagnosis03 medical and health sciences0302 clinical medicineVon Willebrand factorhemic and lymphatic diseasesInternal medicinevon Willebrand FactorVon Willebrand diseaseMedicineHumansPlateletBleeding prediction Bleeding score Blood platelet disorders Child Communication Hemorrhage Humans Inherited platelet disorders Mild-moderate bleeding disorders Platelet Function Tests von Willebrand diseases von Willebrand FactorChildBlood Platelet Disordersddc:616mild-moderate bleeding disordersbiologybusiness.industrymild-moderate bleeding disorderIncidence (epidemiology)CommunicationSettore MED/09 - MEDICINA INTERNAbleeding predictionvon Willebrand Diseases/diagnosis/genetics[SDV.MHEP.HEM]Life Sciences [q-bio]/Human health and pathology/HematologyHematologymedicine.diseaseBlood Platelet Disorders/diagnosis/genetics3. Good healthbleeding scoreInstitutional repositoryvon Willebrand Diseasesmoderate bleeding disordersinherited platelet disordersQuartilebiology.proteinBlood Platelet Disordersvon Willebrand diseasebusinessJournal of thrombosis and haemostasis : JTHREFERENCES
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Improved Radio-Cesium Detection Using Quantitative Real-Time Autoradiography

2023

Cesium-134 and -137 are prevalent, long-lived, radio-toxic contaminants released into the environment during nuclear accidents. Large quantities of insoluble, respirable Cs-bearing microparticles (CsMPs) were released into the environment during the Fukushima Daiichi nuclear accident. Monitoring for CsMPs in environmental samples is essential to understand the impact of nuclear accidents. The current detection method used to screen for CsMPs (phosphor screen autoradiography) is slow and inefficient. We propose an improved method: real-time autoradiography that uses parallel ionization multiplier gaseous detectors. This technique permits spatially resolved measurement of radioactivity while …

microparticlesmathematical methodshärmistyminenmatemaattiset menetelmätelectrical energypaksuuspienhiukkasetdepositionthicknesssähköenergia
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Influence of B content on microstructure, phase composition and mechanical properties of CVD Ti(B,N) coatings

2022

Within this work the effect of the B content on the microstructure, phase composition and mechanical properties of CVD Ti(B,N) coatings is investigated. Ti(B,N) coatings with B contents from 0 (fcc-TiN) to ∼5, ∼15, ∼30, ∼45 and 66 (h-TiB2) at.% have been deposited by CVD. The elemental composition of the coatings was confirmed by ERDA and their microstructure was investigated using XRD and SEM. With increasing B content, a transition from a fcc to a h-dominated structure via dual-phase fcc/h-Ti(B,N) was observed, which was accompanied by a decreasing grain size from the µm to nm range. Combinatorial use of Raman spectroscopy, XPS and APT measurements indicated B-rich grain boundary segregat…

mikrorakenteetmicromechanicskemiallinen kaasufaasipinnoitusTi(BN)chemical vapor deposition (CVD)boridestitaaniboriditGeneral Materials Scienceatom probe tomography (APT)pinnoitteetfysikaaliset ominaisuudet
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Chemical, mineralogical and isotopic observations on hypersaline surficial deposits from Trapani evaporation ponds.

2010

mineralogy isotopic ratio hypersaline surficial depositsSettore GEO/08 - Geochimica E Vulcanologia
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Late Pleistocene vertebrate - bearing deposits at San Teodoro Cave (North-Eastern Sicily): Preliminary data on faunal diversification and chronology

2008

Abstract This paper deals with the chronology and the possible correlations among levels of different excavated areas in the Pleistocene vertebrate-bearing deposits at the large San Teodoro Cave (North-Eastern Sicily). Two trenches have been excavated along the eastern side of the cave, located at a distance from the entrance, respectively, of 8 m ( α trench) and 28 m ( β trench) and at different depths. Lithological features, biometrical data from small mammals and ecological data from molluscs point to similar environmental conditions for the α trench deposits and those located along the eastern wall of the cave in the eastern part of the β trench. The same evidence, and the taphonomic fe…

molluscslate pleistocenegeographyTaphonomygeography.geographical_feature_categoryPleistocenebiologyVertebrateSettore GEO/01 - Paleontologia E PaleoecologiaArchaeologylate pleistocene; molluscs; sicily; vertebratesPaleontologyCavebiology.animalTrenchsicilyLate Pleistocene Sicily Vertebrates Chronology Cave depositsvertebratesMediterranean IslandsGeologyEarth-Surface ProcessesStratumChronology
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Myotonic dystrophy: candidate small molecule therapeutics

2017

Myotonic dystrophy type 1 (DM1) is a rare multisystemic neuromuscular disorder caused by expansion of CTG trinucleotide repeats in the noncoding region of the DMPK gene. Mutant DMPK transcripts are toxic and alter gene expression at several levels. Chiefly, the secondary structure formed by CUGs has a strong propensity to capture and retain proteins, like those of the muscleblind-like (MBNL) family. Sequestered MBNL proteins cannot then fulfill their normal functions. Many therapeutic approaches have been explored to reverse these pathological consequences. Here, we review the myriad of small molecules that have been proposed for DM1, including examples obtained from computational rational …

musculoskeletal diseases0301 basic medicineTherapeutic gene modulationcongenital hereditary and neonatal diseases and abnormalitiesMutantComputational biologyBiologyMyotonic dystrophyMyotonin-Protein Kinase03 medical and health sciences0302 clinical medicineTrinucleotide RepeatsDrug DiscoveryGene expressionmedicineAnimalsHumansMyotonic DystrophyGenePharmacologyRegulation of gene expressionGeneticsDrug RepositioningRational designmedicine.diseaseSmall moleculeHigh-Throughput Screening Assays030104 developmental biologyGene Expression RegulationDrug Design030217 neurology & neurosurgeryDrug Discovery Today
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Checklist of the Mammal Collection Preserved at the University of Palermo under the Framework of the National Biodiversity Future Center

2023

The latest reorganization of the Vertebrate collections preserved at the “Pietro Doderlein” Museum of Zoology of the University of Palermo (Italy) has made it possible to draw up a check-list of the Mammal taxa present in the stuffed (M), fluid-preserved (ML) and anatomical (AN) collections. The intervention was planned under the National Biodiversity Future Center (NBFC) agenda, focused on the enhancement of Italian natural history museums. The growing interest in museum collections strongly demands databases available to the academic and policy world. In this paper, we record 679 specimens belonging to 157 specific taxa arranged in 58 families and 16 orders. Most of the species (75.1%) co…

museomicEcologyEcological Modelingzoological collectionSettore BIO/05 - Zoologiatissue repositoriemammaliacollection-holding universitienatural history museum; zoological collections; collection-holding universities; mammalia; museomics; tissue repositories; biodiversitynatural history museumAgricultural and Biological Sciences (miscellaneous)biodiversityNature and Landscape ConservationDiversity
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Erratum: De Teresa, J.M. et al. Comparison between Focused Electron/Ion Beam-Induced Deposition at Room Temperature and under Cryogenic Conditions. M…

2020

In Section 3 [...]

n/aMaterials scienceIon beamControl and Systems Engineeringlcsh:Mechanical engineering and machineryMechanical EngineeringAnalytical chemistrylcsh:TJ1-1570ElectronElectrical and Electronic EngineeringDeposition (chemistry)Micromachines
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Review on the Processing and Properties of Polymer Nanocomposites and Nanocoatings and Their Applications in the Packaging, Automotive and Solar Ener…

2017

For the last decades, nanocomposites materials have been widely studied in the scientific literature as they provide substantial properties enhancements, even at low nanoparticles content. Their performance depends on a number of parameters but the nanoparticles dispersion and distribution state remains the key challenge in order to obtain the full nanocomposites’ potential in terms of, e.g., flame retardance, mechanical, barrier and thermal properties, etc., that would allow extending their use in the industry. While the amount of existing research and indeed review papers regarding the formulation of nanocomposites is already significant, after listing the most common applications, this r…

nanodepositNanocompositenanocompositebarrier improvementNanodepositelectrosprayingReviewNanostructured materials:Enginyeria dels materials [Àrees temàtiques de la UPC]light-weight materialslcsh:ChemistryBarrier improvementlcsh:QD1-999self-cleaning surfacesLight-weight materialsMaterials nanoestructuratsElectrosprayingSelf-cleaning surfaces
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Raw data for the publication "Effect of graphene substrate type on formation of Bi2Se3 nanoplates", Sci. Rep. 9, 4791, 2019. https://doi.org/10.1038/…

2020

This dataset contains the raw AFM and SEM measurement data used for the study of stages of formation of Bi2Se3 nanoplates on different substrates and for the statistical analysis of sizes and thicknesses of the nanoplates. The results are published in Sci. Rep. 9, 4791, 2019. https://doi.org/10.1038/s41598-019-41178-1

nanoplatesHiTIMegraphenebismuth selenidephysical vapour deposition
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