Search results for "Erk"
showing 10 items of 2599 documents
Determining hydraulic properties of a loam soil by alternative infiltrometer techniques
2015
Testing infiltrometer techniques to determine soil hydraulic properties is necessary for specific soils. For a loam soil, the water retention and hydraulic conductivity predicted by the BEST (Beerkan Estimation of Soil Transfer parameters) procedure of soil hydraulic characterization was compared with data collected by more standard laboratory and field techniques. Six infiltrometer techniques were also compared in terms of saturated soil hydraulic conductivity, Ks. BEST yielded water retention values statistically similar to those obtained in the laboratory and Ks values practically coinciding with those determined in the field with the pressure infiltrometer (PI). The unsaturated soil hyd…
DETERMINING THE SATURATED HYDRAULIC CONDUCTVITY OF A LOAM SOIL WITH DIFFERENT INFILTROMETER TECHNIQUES
2015
The saturated soil hydraulic conductivity, Ks, is one of the most important soil hydraulic properties since it controls many hydrological processes. This hydrodynamic parameter depends on soil texture and structure and it is very difficult to measure. Infiltrometer techniques are becoming very popular to determine Ks in the field but testing alternative approaches is necessary for specific soil types. For a loam soil, the estimated Ks values with six infiltrometer techniques were compared. The so-called BEST procedure of soil hydraulic characterization, the pressure infiltrometer (PI), single head experiments with both the tension infiltrometer (TI) and the mini disk infiltrometer (MDI), th…
Intestinal CD36 : A long chain fatty acid receptor which controls post prandial hypertriglyceridemia, endotoxemia and intestinal epithelium integrity
2014
Post prandial hypertriglyceridemia represents a risk factor for cardio-vascular diseases and it is associated with metabolic syndrom, obesity, and insulino-resistance. The intestine influences lipid bioavailibility and post prandial hypertriglyceridemia. It controls the quantity and the quality of secreted chylomicrons by adapting its metabolism according to the lipid content of the diet. Nevertheless, the mechanism of dietary lipid detection by the enterocyte is not understood. Our work demonstrates that the transmembrane glycoprotein CD36 is a Long Chain Fatty Acid (LCFA) receptor which triggers ERK1/2 activation. This activation is responsible for the induction of mRNA rate of 3 key prot…
Anti-inflammatory properties of lemon-derived extracellular vesicles are achieved through the inhibition of ERK/NF-κB signalling pathways
2022
Chronic inflammation is associated with the occurrence of several diseases. However, the side effects of anti-inflammatory drugs prompt the identification of new therapeutic strategies. Plant-derived extracellular vesicles (PDEVs) are gaining increasing interest in the scientific community for their biological properties. We isolated PDEVs from the juice of Citrus limon L. (LEVs) and characterized their flavonoid, limonoid and lipid contents through reversed-phase high-performance liquid chromatography coupled to electrospray ionization quadrupole time-of-flight mass spectrometry (RP-HPLC-ESI-Q-TOF-MS). To investigate whether LEVs have a protective role on the inflammatory process, murine a…
Using stage theorizing to make anti-phishing recommendations more effective
2018
Purpose This paper aims to review the behavioral phishing literature to understand why anti-phishing recommendations are not very effective and to propose ways of making the recommendations more effective. The paper also examines how the concept of stages from health communication and psychology can be used to make recommendations against phishing more effective. Design/methodology/approach This literature review study focused on the behavioral phishing literature that has relied on human subjects. Studies were excluded for reasons that included lacking practical recommendations and human subjects. Findings The study finds that phishing research does not consider where victims are residing…
Mental health service users' and professionals' relationship with games and gaming
2017
Background Games and elements of gamification can be utilized in mental healthcare to provide customized interventions for the service users. However, very little evidence exists as to what kind of experiences service users and professionals have towards games and gaming, and what their perceptions of the phenomenon are. This sort of information is needed to help professionals put game-based interventions actively into practice in mental health services. Research objectives The objective is to describe the experiences and perceptions of digital games and gaming from the perspectives of mental health service users and mental health professionals. Methods In this qualitative study, data consi…
Negative Engagement
2018
Negative engagement has steeply increased on the scholarly agenda along with the introduction of real time and social media, though negative experiences and emotions are as such not new phenomena. This chapter takes a future perspective and focuses on negative stakeholder engagement online in the context of organizations and brands, which increasingly face visible forms of negative stakeholder emotions or even fierce "shit storms". It begins by defining what negative stakeholder engagement refers to in the context of organizations and brands. The chapter introduces the development of negative engagement via related concepts. After introducing the concepts, the process and the outcomes of ne…
Korkeakouluohjauksen mahdollisuudet verkossa : Jyväskylän yliopiston kasvatustieteellisen tiedekunnan ensimmäisen vuoden opiskelijoiden verkkotottumu…
2011
Ohjausalalla on herätty sosiaalisen median ja verkko-ohjauksen tutkimukseen. Tutkimuksen tarve onkin ilmeinen sillä, jos ohjaus haluaa olla ihmisten elämän kannalta relevanttia, tulee sen olla valmis muuttumaan ja mukautumaan tietoyhteiskunnan vaatimuksiin. Jyväskylässä tutkitaan sosiaalisen median hyödyntämistä korkea-asteen ohjauksen ja työelämätaitojen kehittämisessä osana ESR-hanketta ”Ohjauksen ja työelämätaitojen kehittäminen korkea-asteella”. Tämän pro gradu -tutkielman aineisto on osa tätä sosiaalista mediaa ja ohjausalaa koskevaa tutkimushanketta. Tutkimuksessani pyrin kvantitatiivisesti selvittämään ESR-hankkeesta saadun aineiston avulla Jyväskylän yliopiston kasvatustieteellisen …
Vuorovaikutteiset leikit Pikku Kakkosen netissä
2013
Tämän pro gradu -tutkielman pyrkimyksenä oli ymmärtää ja analysoida Pikku Kakkosen nettiä ja erityisesti sen vuorovaikutteisia leikkejä. Pikku Kakkosen nettiä ja sen sisältöjä tarkastellaan kokonaisuutena. Tämän gradun muoto onkin työnäytegradu. Projektin tavoitteena oli tuottaa tietoa siitä, miten uudenlainen verkkoympäristö ja -sisällöt aktivoivat lapsia sekä miten sivuston vuorovaikutuksellisia elementtejä pystyttäisiin kehittämään edelleen. Projektiin sisältyy myös tutkimus lasten osallistumisesta juontajan simuloimaan vuorovaikutuskäyttäytymiseen. Projektin tutkimus toteutettiin havainnoimalla kuutta 3-5-vuotiasta tutkimushenkilöä. Havainnoinnissa virikkeenä käytetyt vuorovaikutteiset …
Motivational drivers of behavioral online brand engagement in content consumption context : examining brand commitment and trust in online content as…
2015
The Internet has become increasingly important for companies in recent years. However, online environment possesses many challenges for both managers and researchers. Moreover, it is not until recently engagement concept has begun to emerge in the marketing literature. However, it is known that engagement has a strong influence on many favorable customer outcomes. Thus, engagement is a fruitful research topic in online environment. The purpose of this explanatory study is to examine behavioral dimension of online brand engagement in context of content consumption. This study examines the effects of five motivational drivers (community, information, entertainment, identity, and remuneration)…