Search results for "Estudios Prospectivos"

showing 10 items of 21 documents

Dietary Inflammatory Index and Incidence of Cardiovascular Disease in the PREDIMED Study

2015

Previous studies have reported an association between a more pro-inflammatory diet profile and various chronic metabolic diseases. The Dietary Inflammatory Index (DII) was used to assess the inflammatory potential of nutrients and foods in the context of a dietary pattern. We prospectively examined the association between the DII and the incidence of cardiovascular disease (CVD: myocardial infarction, stroke or cardiovascular death) in the PREDIMED (Prevención con Dieta Mediterránea) study including 7216 high-risk participants. The DII was computed based on a validated 137-item food frequency questionnaire. Multivariate-adjusted hazard ratios (HR) and 95% confidence intervals of CVD risk we…

MaleMediterranean dietmodelos de riesgos proporcionaleshumanosSistema cardiovascular -- Malaltiesestudios de seguimientoDiet MediterraneanDietary inflammatory indexBody Mass Indexcardiovascular diseaseRisk Factorsestudios prospectivosSurveys and QuestionnairesNutsProspective StudiesProspective cohort studymediana edadAged 80 and overancianoNutrition and Dieteticsdietaresultado del tratamientoIncidenceIncidence (epidemiology)Hazard ratioMiddle AgedCardiovascular diseaseInflamaciódeterminación del punto finalCardiovascular diseasesTreatment OutcomeQuartileCardiovascular Diseasesdietary inflammatory indexFemalelcsh:Nutrition. Foods and food supplyPREDIMEDmedicine.medical_specialtyEndpoint DeterminationPromoció de la salutenfermedades cardiovasculareslcsh:TX341-641Context (language use):Ciencias de la Salud::Nutrición y dietética [Materias Investigacion]incidenciaArticleMediterranean cookinginflamaciónInternal medicineCuina mediterràniaingesta energéticamedicinefactores de riesgoHumansanálisis multifactorialOlive OilAgedProportional Hazards ModelsInflammationMalalties cardiovascularsbusiness.industryProportional hazards modelíndice de masa corporalDietSurgerynuecesMultivariate AnalysisHealth promotionEnergy IntakebusinessBody mass indexFollow-Up StudiesFood ScienceNutrients

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Cardiovascular disease, chronic kidney disease, and diabetes mortality burden of cardiometabolic risk factors from 1980 to 2010: A comparative risk a…

2014

High blood pressure, blood glucose, serum cholesterol, and BMI are risk factors for cardiovascular diseases and some of these factors also increase the risk of chronic kidney disease and diabetes. We estimated mortality from cardiovascular diseases, chronic kidney disease, and diabetes that was attributable to these four cardiometabolic risk factors for all countries and regions from 1980 to 2010.

MaleSettore MED/09 - Medicina Internakidney diseaseEndocrinology Diabetes and Metabolismhumanoscoste de las enfermedadesDiseaseGlobal HealthCohort StudiesEndocrinologyCost of Illnesscardiovascular diseaseHealth TransitionRisk Factorstransición sanitariaestudios prospectivosRenal Insufficiency Chronic -- complications -- epidemiology -- mortalityevaluación de riesgosRenal InsufficiencyProspective StudiesChronicestudios de cohortesMetabolic Syndromeeducation.field_of_studydiabetesMortality rateAge Factors; Cardiovascular Diseases; Cohort Studies; Cost of Illness; Diabetes Complications; Female; Health Surveys; Humans; Male; Metabolic Syndrome X; Prospective Studies; Renal Insufficiency Chronic; Risk Assessment; Risk Factors; Sex Factors; Spatio-Temporal Analysis; Global Health; Health Transition; Internal Medicine; Endocrinology Diabetes and Metabolism; EndocrinologyMetabolic Syndrome XCardiovascular Diseases -- complications -- epidemiology -- mortalityAge FactorsCardiovascular diseaseDiabetes Mellitus chronic kidney diseaseDiabetes Complications -- epidemiology -- mortalitySciences bio-médicales et agricolesDiabetes and MetabolismCardiovascular Diseasesencuestas de saludFemaleanálisis temporoespacialRisk assessmentcomplicaciones de la diabetesinsuficiencia renalmedicine.medical_specialtyCardiovascular disease; kidney disease; diabetes mortalityPopulationenfermedades cardiovascularesMetabolic Syndrome X -- complications -- epidemiology -- mortalityRisk AssessmentArticleDiabetes ComplicationsSex FactorsSpatio-Temporal Analysiscardiovascular disease; chronic kidney disease; diabetes; mortalityInternal medicineEnvironmental healthDiabetes mellitusmedicineAge Factors; Cardiovascular Diseases; Cohort Studies; Cost of Illness; Diabetes Complications; Female; Health Surveys; Humans; Male; Metabolic Syndrome X; Prospective Studies; Renal Insufficiency Chronic; Risk Assessment; Risk Factors; Sex Factors; Spatio-Temporal Analysis; Global Health; Health Transition; Endocrinology Diabetes and Metabolism; Internal Medicine; EndocrinologyInternal Medicinefactores de riesgoHumansRisk factorRenal Insufficiency Chroniceducationbusiness.industrydiabetes mortalitymedicine.diseasemortalityHealth SurveysEndocrinologyRelative riskAge Factors; Cardiovascular Diseases/complications; Cardiovascular Diseases/epidemiology; Cardiovascular Diseases/mortality; Cohort Studies; Cost of Illness; Diabetes Complications/epidemiology; Diabetes Complications/mortality; Female; Global Health; Health Surveys; Health Transition; Humans; Male; Metabolic Syndrome X/complications; Metabolic Syndrome X/epidemiology; Metabolic Syndrome X/mortality; Prospective Studies; Renal Insufficiency Chronic/complications; Renal Insufficiency Chronic/epidemiology; Renal Insufficiency Chronic/mortality; Risk Assessment; Risk Factors; Sex Factors; Spatio-Temporal Analysisbusinesschronic kidney diseaseKidney diseaseThe Lancet Diabetes and Endocrinology

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Impact of psychosocial factors on cardiovascular morbimortality: a prospective cohort study

2014

[Background] Whilst it is well known that psychosocial determinants may contribute to cardiovascular diseases (CVD), data from specific groups are scarce. The present study aims to determine the contribution of psychosocial determinants in increasing the risk of cardiovascular events (myocardial infarction and stroke), and death from CVD, in a high risk adult population.

MaleTime Factorsmodelos de riesgos proporcionalesEpidemiologyhumanosdepresiónMyocardial Infarction1471-2261Social supportdisparidades en el estado de saludClinical trialsRisk Factorsestudios prospectivosCause of Deathevaluación de riesgosMedicineLongitudinal StudiesProspective StudiesProspective cohort studyStrokemediana edadHealth inequalitiesCause of deathAged 80 and overeducation.field_of_studyancianoDepressionFactors de risc en les malaltiesHazard ratioMiddle AgedPrognosisStrokepronósticoSocioeconomic positionCardiovascular diseasesEstudi de casosEducational StatusFemaleRisk assessmentCardiology and Cardiovascular MedicinePsychosocialResearch Articlemedicine.medical_specialtyRisk factors in diseasesPopulationAcute myocardial infarctionRisk AssessmentEducational levelfactores de tiempocausas de muerteInternal medicinefactores de riesgoHumansanálisis multifactorialaccidente cerebrovascularcardiovascular diseaseseducationEpidemiologiainfarto de miocardioAgedProportional Hazards Modelsbusiness.industryProportional hazards modelMalalties cardiovascularsHealth Status Disparitiesmedicine.diseaseapoyo socialMorbiditatSpainMultivariate AnalysisPhysical therapyHousingCardiovascular deathestudios longitudinalesCase studiesMorbiditybusinessAssaigs clínics

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Mercury exposure and risk of cardiovascular disease: a nested case-control study in the PREDIMED (PREvention with MEDiterranean Diet) study

2017

Background: Substantial evidence suggests that consuming 1-2 servings of fish per week, particularly oily fish (e.g., salmon, herring, sardines) is beneficial for cardiovascular health due to its high n-3 polyunsaturated fatty acid content. However, there is some concern that the mercury content in fish may increase cardiovascular disease risk, but this relationship remains unclear. Methods: The PREDIMED trial included 7477 participants who were at high risk for cardiovascular disease at baseline. In this study, we evaluated associations between mercury exposure, fish consumption and cardiovascular disease. We randomly selected 147 of the 288 cases diagnosed with cardiovascular disease duri…

Malecompuestos de metilmercurioTime Factorsmodelos logísticosMediterranean diethumanos030204 cardiovascular system & hematologyDiet MediterraneanRecommended Dietary AllowancesDieta mediterrània1471-22610302 clinical medicineRisk Factorsestudios prospectivosevaluación de riesgosOdds RatioOily fishWater Pollutants030212 general & internal medicineProspective StudiesToenail biomarkeruñasmediana edadCiències de la salutAged 80 and overeducation.field_of_studyBioquímica y tecnologíaanciano:Ciencias de la Salud::Salud pública [Materias Investigacion]dietaMALALTIES CARDIOVASCULARSMethylmercury CompoundsMiddle Agedcontaminantes del aguaCardiovascular diseaseCiencias de la saludcociente de probabilidades relativasBiochemistry and technologyCardiovascular DiseasesBody BurdenFemaleCardiology and Cardiovascular Medicinecantidad dietética recomendadaResearch ArticlePREDIMEDmedicine.medical_specialtyPopulationestudios de casos y controlesenfermedades cardiovasculareschemistry.chemical_elementFood ContaminationSistema cardiovascular malaltiesBioquímica i biotecnologiaRisk Assessment03 medical and health sciencesalimentos del marfactores de tiempoEnvironmental healthMediterranean dietmedicineHumansfactores de riesgoMercuri -- Toxicologiaanálisis multifactorialeducationCardivascular diseaseAgedbusiness.industryCase-control studyHealth sciencesOdds ratioMercuryProtective FactorsSurgeryMercury (element)DietLogistic ModelsFishchemistrySeafoodNailsSpainRelative riskCase-Control StudiesNested case-control studyMultivariate AnalysisbusinessWater Pollutants Chemicalcarga corporal

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Dietary Quality Changes According to the Preceding Maximum Weight: A Longitudinal Analysis in the PREDIMED-Plus Randomized Trial

2020

One-year dietary quality change according to the preceding maximum weight in a lifestyle intervention program (PREDIMED-Plus trial, 55–75-year-old overweight or obese adults; n = 5695) was assessed. A validated food frequency questionnaire was used to assess dietary intake. A total of 3 groups were made according to the difference between baseline measured weight and lifetime maximum reported weight: (a) participants entering the study at their maximum weight, (b) moderate weight loss maintainers (WLM), and (c) large WLM. Data were analyzed by General Linear Model. All participants improved average lifestyle. Participants entering the study at their maximum weight were the most susceptible …

Malecumplimiento del pacienteMediterranean diethumanosOverweightDiet Mediterraneanlaw.inventionencuestas sobre dietasClinical trials0302 clinical medicineRandomized controlled trialBehavior TherapyWeight losslawestudios prospectivosWeight managementMedicineLongitudinal StudiesProspective Studies030212 general & internal medicineskin and connective tissue diseasesmediana edadancianoNutrition and Dieteticssobrepesodietaresultado del tratamientoMaximum weightmodelos linealesMiddle AgedWeight Reduction ProgramsTreatment OutcomeBody imageDiet qualityCardiovascular Diseasesestilo de vidaprogramas de reducción de pesoFemaleDietaterapia conductistadietary patternDiet Healthypérdida de pesomedicine.symptommaximum weightlcsh:Nutrition. Foods and food supplybody imageenfermedades cardiovascularesPes corporalDietary patternlcsh:TX341-641030209 endocrinology & metabolismDiet SurveysArticle03 medical and health sciencesMediterranean dietWeight LossHumansObesityLife StyleobesidadAgedGeneral linear modelbusiness.industryPREDIMED-PlusBody weightOverweightPredimedDietLinear ModelsPatient Complianceestudios longitudinalesBody-Weight Trajectorysense organsbusinessAssaigs clínicsFood ScienceDemography

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Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multice…

2018

Background Surgical site infection (SSI) is one of the most common infections associated with health care, but its importance as a global health priority is not fully understood. We quantified the burden of SSI after gastrointestinal surgery in countries in all parts of the world. Methods This international, prospective, multicentre cohort study included consecutive patients undergoing elective or emergency gastrointestinal resection within 2-week time periods at any health-care facility in any country. Countries with participating centres were stratified into high-income, middle-income, and low-income groups according to the UN's Human Development Index (HDI). Data variables from the Globa…

Malehumanosfactores socioeconómicospaíses desarrolladosGlobal Healthglobal suregryincidenciaArticleNOCohort StudiesRisk Factorspaíses en desarrolloestudios prospectivossurgical site infection; global suregry; human development indexfactores de riesgoHumansSurgical Wound Infectiongastrointestinal surgeryProspective Studiesestudios de cohortesDeveloping CountriesPovertyDigestive System Surgical ProceduresCross InfectionDeveloped CountriesIncidencesurgical site infectionssurgical site infectioninfectionprocedimientos quirúrgicos del sistema digestivoInfectious Diseases surgical site infection gastrointestinal surgeryInfectious DiseasesSocioeconomic Factorshuman development indexinfección de la herida operatoriasurgical siteFemaleinfección hospitalaria

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Lysine pathway metabolites and the risk of type 2 diabetes and cardiovascular disease in the PREDIMED study: results from two case-cohort studies

2019

[Background]: The pandemic of cardiovascular disease (CVD) and type 2 diabetes (T2D) requires the identification of new predictor biomarkers. Biomarkers potentially modifiable with lifestyle changes deserve a special interest. Our aims were to analyze: (a) The associations of lysine, 2-aminoadipic acid (2-AAA) or pipecolic acid with the risk of T2D or CVD in the PREDIMED trial; (b) the effect of the dietary intervention on 1-year changes in these metabolites, and (c) whether the Mediterranean diet (MedDiet) interventions can modify the effects of these metabolites on CVD or T2D risk. [Methods]: Two unstratified case-cohort studies nested within the PREDIMED trial were used. For CVD analyses…

Malelcsh:Diseases of the circulatory (Cardiovascular) systemTime FactorsMediterranean dietEndocrinology Diabetes and MetabolismhumanosDiseaseType 2 diabetes030204 cardiovascular system & hematologyDiet Mediterraneanchemistry.chemical_compound0302 clinical medicineRisk Factorsestudios prospectivosevaluación de riesgosMetabolites030212 general & internal medicineProspective Studiesmediana edadOriginal InvestigationPipecolic acidRandomized Controlled Trials as TopicAged 80 and overancianodietaácidos pipecólicosensayos clínicos controlados aleatorizados como asuntoresultado del tratamientoIncidenceType 2 diabetesMiddle AgedCardiovascular disease3. Good healthPrimary PreventionTreatment OutcomeCardiovascular DiseasesPipecolic AcidsFemaleCardiology and Cardiovascular Medicineconducta de reducción del riesgoCohort studymedicine.medical_specialtyenfermedades cardiovascularesácido 2-aminoadípicoRisk Assessmentincidencia03 medical and health sciencesfactores de tiempoInternal medicineDiabetes mellitusmedicineDiabetes Mellitusfactores de riesgoHumansAngiologyAgedProportional hazards modelbusiness.industryLysinemedicine.diseaseDietlisinaDietary interventionchemistryDiabetes Mellitus Type 2lcsh:RC666-701business2-Aminoadipic AcidRisk Reduction BehaviorBiomarkers

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Global variation in anastomosis and end colostomy formation following left-sided colorectal resection

2019

Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods: This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associ…

Malemodelos logísticosmedicine.medical_treatmenthumanossurgial careColorectal Neoplasmpaíses desarrolladosLogistic regressionoutcomesGlobal Healthurgencias médicas0302 clinical medicinepaíses en desarrolloSurgicalestudios prospectivosColostomy80 and overglobalsurg030212 general & internal medicineProspective StudiesProspective cohort studyMultivariate Analysimediana edadCancerAged 80 and overEmergencieancianoAnastomosis colorectal resection colostomyAnastomosis SurgicalColostomyGeneral MedicineMiddle Agedadultocolostomy; colorectal cancer; human developlment index3. Good healthColo-Rectal Cancertraditional healersElective Surgical Procedures030220 oncology & carcinogenesisFemaleColorectal Neoplasms6.4 Surgerylow incomeCohort studyHumanDeveloped CountrieAdultAdult; Aged; Aged 80 and over; Anastomosis Surgical; Colorectal Neoplasms; Colostomy; Elective Surgical Procedures; Emergencies; Female; Global Health; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Developed Countries; Developing Countriesmedicine.medical_specialtyneoplasias colorrectalesLogistic Modelcancer anastomosis surgical income stomas colostomy procedure colorectal resection end colostomy emergency surgical procedure human development indexdelayAnastomosishuman developlment indexPerforation (oil well)lcsh:Surgerycolorectal cancerAnastomosisGlobalSurg CollaborativeNO03 medical and health sciencesCase mix indexClinical ResearchmedicinecancerHumansanálisis multifactorialDeveloping CountriesAgedemergency abdominal surgery low income surgial care traditional healers cancer mortality outcomes delayElective Surgical Procedurebusiness.industryKirurgiDeveloped Countriesleft colon resection anastomosis end colostomyEvaluation of treatments and therapeutic interventionslcsh:RD1-811Odds ratiomortalitySurgeryProspective StudieLogistic ModelsMultivariate AnalysisSurgeryEmergenciesbusinessDigestive Diseasescolostomíaemergency abdominal surgery

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Residential Exposure to Outdoor Air Pollution during Pregnancy and Anthropometric Measures at Birth in a Multicenter Cohort in Spain

2011

Background: A growing body of research suggests that prenatal exposure to air pollution may be harmful to fetal development. We assessed the association between exposure to air pollution during pregnancy and anthropometric measures at birth in four areas within the Spanish Children’s Health and Environment (INMA) mother and child cohort study. Methods: Exposure to ambient nitrogen dioxide (NO2) and benzene was estimated for the residence of each woman (n = 2,337) for each trimester and for the entire pregnancy. Outcomes included birth weight, length, and head circumference. The association between residential outdoor air pollution exposure and birth outcomes was assessed with linear regress…

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Air pollution exposure during pregnancy and reduced birth size: a prospective birth cohort study in Valencia, Spain

2010

Abstract Background Maternal exposure to air pollution has been related to fetal growth in a number of recent scientific studies. The objective of this study was to assess the association between exposure to air pollution during pregnancy and anthropometric measures at birth in a cohort in Valencia, Spain. Methods Seven hundred and eighty-five pregnant women and their singleton newborns participated in the study. Exposure to ambient nitrogen dioxide (NO2) was estimated by means of land use regression. NO2 spatial estimations were adjusted to correspond to relevant pregnancy periods (whole pregnancy and trimesters) for each woman. Outcome variables were birth weight, length, and head circumf…

medicine.medical_specialtyEmbarazoBirth weightHealth Toxicology and MutagenesisNitrogen Dioxidelcsh:RC963-969PregnancyEstudios prospectivosmedicine:Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants::Air Pollutants [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Environmental Pollution::Environmental Exposure::Maternal Exposure [Medical Subject Headings]Birth WeightBody SizeHumansContaminantes del aireProspective StudiesProspective cohort study:Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Reproductive Physiological Phenomena::Reproductive Physiological Processes::Reproduction::Pregnancy [Medical Subject Headings]Vehicle Emissions:Geographicals::Geographic Locations::Europe::Spain [Medical Subject Headings]PregnancyAir PollutantsInhalation Exposurebusiness.industryObstetricslcsh:Public aspects of medicineResearchPublic Health Environmental and Occupational HealthInfant Newbornlcsh:RA1-1270Odds ratioAnthropometrymedicine.disease:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies::Prospective Studies [Medical Subject Headings]Exposición maternaMaternal ExposureSpainCohortInfant Small for Gestational Agelcsh:Industrial medicine. Industrial hygieneSmall for gestational ageFemaleValenciabusinessCohort studyEnvironmental Monitoring

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