Search results for "EuP"
showing 10 items of 423 documents
Efficiency of antidepressant drugs as monoamine reuptake inhibitors: analysis of the hydrophobicity influence using biopartitioning micellar chromato…
2004
The reuptake blockade of biogenic amines by antidepressants is related not only to their therapeutics effects, but also to their side effects and potential drug-drug interactions. As an alternative to classical quantitative structure-activity relationships studies, in this work we propose different quantitative retention-activity relationships (QRAR) models that are able to describe the monoamine reuptake inhibition by antidepressants. The retention of compounds is measured using a biopartitioning micellar chromatography (BMC) system that can simulate the same hydrophobic, electronic and steric molecular interactions as those that condition drug activity. Since all the compounds considered …
North Mesopotamian Comb-Incised and Comb-Impressed Pottery
2014
Tis contribution focuses on a distinctive kind of pottery decoration, geometric in nature and characterised by multiple parallel line incisions and/or impressions obtained before fring by means of a comb-like toothed tool operating on the potter’s wheel; therefore, in the archaeological literature it is usually referred to as “Comb-incised Ware” or, more generally, “Combed Ware”.
Elecciones primarias en España. 1993-2015
2015
“Elecciones primarias en España. 1993-2015 ” analiza la intro¬ducción y desarrollo de las elecciones primarias de los partidos políti¬cos en España, y como una forma de participación típica de la política de los EE.UU., va consiguiendo arraigar en los partidos españoles. Será el PSOE el primero que implante el sistema de primarias (Con¬ferencia Política del PSPV en 1993); después en las elecciones pri¬marias para elegir candidato a la Presidencia del Gobierno de España (Almunia-Borrell), por elección directa entre todos los afiliados socia¬listas (1998); y a través de primarias abiertas a simpatizantes en la elección del candidato socialista a la Presidencia de la Generalitat Valenciana (20…
Primarias en la Comunitat Valenciana. 2014-2015. Partidos valencianos y primarias para la elección de candidato a la Presidencia de la Generalitat en…
2015
A lo largo de 2014 y principios de 2015, casi todos los partidos políticos que se van a presentar a las elecciones de 2015 (locales, autonómicas y generales) van a realizar algún tipo de primarias para la selección de sus candidatos, a excepción del PP. Los partidos que celebran primarias abiertas en la Comunidad Valenciana -CV- son el PSPV - presenciales-, EUPV, Compromís y Podemos, estos tres admiten también voto por Internet y correo. Solo votaban en primarias los afiliados en UPyD (sin avales) y C´s (aval 10% censo). Sin primarias el PP. El candidato lo decide el dedo de Mariano Rajoy.
Comparative Analysis of the Vascular Actions of Diterpenes Isolated from Euphorbia canariensis
1998
Abstract We have analysed the effects of 2,3-diepiingol 7,12-diacetate-8-isobutyrate (compound 1), ingenol-3-angelate-17-benzoate (compound 2), ingenol-3-angelate-17-benzoate-20-acetate (compound 3) and 3,5,7,8,9,15-hexahydroxyjatropha-6(17),11-dien-14-one-5,8-bis(2-methylbutyrate)-7-(2-methylpropionate) (compound 4), four diterpenes isolated from E. canariensis, on the isometric tension developed by isolated rabbit basilar and carotid arteries. Concentration-response curves to these compounds were obtained cumulatively in both arteries at resting tension and active tone (KCl, 50 mM). At resting tension a concentration-dependent contraction was induced by the four compounds. In the basilar …
Violence Through Words: Cultural Aspects and Performative Agency
2020
This chapter aims at describing the ways and ploys used by words (in the various public and private contexts where they define relations) conveying a form of symbolic violence aimed at classifying genders as they play out their respective identity roles. To this end, the author refers to “euphemized discourse” (Bourdieu, 1993) and the concept of “agency” (Duranti, Etnopragmatica. La forza nel parlare. Carocci Editore, Rome, Italy, 2007) in order to describe the process of naturalization of discursive practices geared towards affirmation of the androcentric system of language. Here, a variant of Mediterranean culture which remains patriarchal and sexist is examined by means of discourse anal…
"Per via di levare". Scavare e sottrarre in architettura
2014
Scavare, dal latino excavare (ex-cavare), possiede etimologicamente il significato di “rendere cavo” mediante l’azione del subtrahĕre (sottrarre). Tuttavia il significato del termine all’interno della sua necessaria disambiguazione non può essere inteso limitatamente alla luce dell’etimologia latina. Si dirà allora che la tecnica dello scavo è opposta e complementare alla tecnica dell’accumulazione. È un procedere per sottrazione di volumi, un operare in negativo per asportazione di materiale, erodendo, cavando ed estraendo. Il saggio indaga, attraverso un intenso per quanto lacunoso excursus tra le esperienze della contemporaneità l'emergere del archetipico della dimensione ipogea dell’arc…
Du rap, du peuple et du populaire – essais de définitions
2019
International audience; No abstract.
Aneuploid IMR90 cells induced by depletion of pRB, DNMT1 and MAD2 show a common gene expression signature
2019
Chromosome segregation defects lead to aneuploidy which is a major feature of solid tumors. How diploid cells face chromosome mis-segregation and how aneuploidy is tolerated in tumor cells are not completely defined yet. Thus, an important goal of cancer genetics is to identify gene networks that underlie aneuploidy and are involved in its tolerance. To this aim, we induced aneuploidy in IMR90 human primary cells by depleting pRB, DNMT1 and MAD2 and analyzed their gene expression profiles by microarray analysis. Bioinformatic analysis revealed a common gene expression profile of IMR90 cells that became aneuploid. Gene Set Enrichment Analysis (GSEA) also revealed gene-sets/pathways that are …
DNA integrity, growth pattern, spindle formation, chromosomal constitution and imprinting patterns of mouse oocytes from vitrified pre-antral follicl…
2010
Cryopreservation of follicles for culture and oocyte growth and maturation in vitro provides an option to increase the number of fertilizable oocytes and restore fertility in cases where transplantation of ovarian tissue poses a risk for malignant cell contamination. Vitrification for cryopreservation is fast and avoids ice crystal formation. However, the influences of exposure to high concentrations of cryoprotectants on follicle development, oocyte growth and maturation, and particularly, on the DNA integrity and methylation imprinting has not been studied systematically. Follicle survival and development, DNA damage, oocyte growth patterns, maturation, spindle formation and chromosomal c…