Search results for "EuP"
showing 10 items of 423 documents
Phytoplankton assemblages in reservoirs: Is it chemical or physical constraints which regulate their structure?
1998
Data on phytoplankton assemblages and the correspondent environmental variables, collected in a limnological investigation carried out on 21 Sicilian reservoirs between 1987 and 1988, were ordered to clarify which physical (light availability, mixing depth), chemical (nutrient availability) and biological (grazing pressure) parameters modulate the structure of the assemblages. In particular, data sets were analyzed using CANOCO 3.1. The results of the analysis have shown that physical factors are more important in selecting species for those environments subject to pronounced water-level fluctuations. The reasons of such strong influence may be understood in the secondary modifications that…
Winter feeding leads to a shifted phenology in the browntail moth Euproctis chrysorrhoea on the evergreen strawberry tree Arbutus unedo
2010
1 The browntail moth Euproctis chrysorrhoea is a highly polyphagous univoltine forest pest. Although its young larvae usually overwinter in diapause from early autumn to the beginning of spring, winter larval feeding has been reported when this species feeds on the evergreen woody shrub strawberry tree Arbutus unedo. 2 The present study investigated life-history traits of four populations of E. chrysorrhoea feeding on A. unedo, including phenology of the different life stages, larval feeding activity and diapause incidence. By modelling the relationship between larval size and host plant leaf persistence, elevation and mean annual temperature, we also studied larval development in ten popul…
Tell Shiyukh Tahtani on the Euphrates. Highlights of the last excavation seasons
2010
In recent years (2006-09) the University of Palermo Euphrates expedition has continued rescue excavations at Tell Shiyukh Tahtani (the “Lower Hill of Sheikhs”) as part of the Tishreen Dam Salvage Project. Located on the left bank of the River south of Jerablus, in the land that once was the Carchemish district, this small mound has revealed a long occupation sequence from around 3.000 B.C. to Byzantine and early Islamic times. During the last three seasons we mainly concentrated in the investigation of the eastern slope of the upper tell (Area CD), where a continuous Bronze Age occupation has been detected. Apart from the later levels (EB IV, Middle and Late Bronze Age), one of the main goa…
Study of the combined effects of CDK1 inhibitors and senolytic drugs for the clearance of aneuploid-senescent cells
2022
Despite the progresses in discovering new therapeutic drugs and treatments, cancer is still one of the main causes of death. The biggest part of available treatments, moreover, is not always effective against tumour spread and it also has negative effects on the healthy tissues of the individual. For this reason, it is extremely relevant to find new strategies to avoid side effects during the anti-cancer therapies. Aneuploidy, an aberrant number of chromosomes in the cell, is a typical condition of cancer cells caused mainly by segregation errors and chromosomal instability (CIN). CIN is a process by which higher rate of chromosome segregation defects occurs by different mechanisms (chromos…
Exploring natural products-based cancer therapeutics derived from egyptian flora
2020
Abstract Ethnopharmacological relevance Egyptian plants are a rich source of natural molecules, representing considerable biodiversity due to climate variations between the Northern, Southern, Eastern and Western regions of the country. Sinai is considered a precious nature reserves preserving flora, fauna, marine organisms, and historical habitats with ancient origins. Here, traditional medicinal approaches have been used for hundreds of years. Healthy lifestyles, low levels of stress and microbial infections, and a dependence on flora and herbal medicine might in combination explain why the burden of cancer is lower in some regions than in others. Aim of the study The primary aim of this …
The uses of urban fortresses of Burgundy in the modern times
2011
Study the urban fortresses of Burgundy means interesting in the relationships between, on the one hand, these buildings and their occupants and, on the other hand, the society in which they are located. A city with a castle isn’t necessarily a castral town. The castle can generate, move or expand a city. Its representation also reflects its place in society. The genesis of the city often has consequences throughout the modern times on relationships between the castle and the city. In wartime, the castle can be the ruin or the salvation for the city. In peacetime, it’s most often a dead weight : it must be maintained, sometimes its garnison must be maintained too. But in the dialectic cities…
Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-…
2002
This report is focused on the apoptotic effect induced by MG132, an inhibitor of 26S proteasome, in human hepatoma HepG2 cells. The results were compared with those obtained with non-transformed human Chang liver cells. MG132 reduced the viability of HepG2 cells in a time- and dose-dependent manner. The effect was in tight connection with the induction of apoptosis, as indicated by fluorescence microscopy and cytometric analysis, and was accompanied by a remarkable increase in the production of H2O2 and a reduction in mitochondrial transmembrane potential (Deltapsim). In addition cell death was prevented by antioxidants such as GSH, N-acetylcysteine or catalase. Western blot analysis showed…
Tetrasomy 18p de novo: Identification by FISH with conventional and microdissection probes and analysis of parental origin and formation by short seq…
1996
We report a de novo supernumerary isochromosome 18p in a child with tetrasomy 18p, analyzed by a straightforward combination of cytogenetic and molecular cytogenetic methods. The diagnostic procedure consisted of standard banding techniques and fluorescence in situ hybridization (FISH) with centromere and library DNA probes for chromosome 18, and 18p-specific FISH probes prepared by chromosome microdissection and in vitro amplification. The maternal origin as well as the most probable cell stages of formation of the supernumerary isochromosome were determined by typing of short sequence repeats (SSRs). The pattern of allelic distribution suggests a nondisjunction during meiosis followed by …
Pigmentary mosaicism in hypomelanosis of Ito
1998
We report on a female with mental and motor retardation, facial dysmorphism, abnormal pigmentation reminiscent to hypomelanosis of Ito (HI), and karyotypic mosaicism involving a small supernumerary marker chromosome. The marker chromosome was defined by fluorescence in situ hybridisation (FISH) as a ring X chromosome with breakpoints in the juxtacentromeric region. FISH analysis showed that the ring does not include the XIST locus at the X-inactivation centre and, therefore, may not be subject to X inactivation. X-inactivation studies with the HUMARA (human androgen receptor) and FMR1 assay showed a skewed X-inactivation pattern (85:15) with preferential inactivation of the paternal X chrom…
Cell cycle: Aetiology of age-associated aneuploidy: a mechanism based on the 'free radical theory of ageing'
1995
A general model is put forward to explain the mechanism by which age-associated aneuploidies are produced. This is based on the free radical theory of ageing, which assumes a rise in oxidative stress with age. It is proposed that determination of indicators of oxidative stress in oocytes from various sources could be a first step in the testing of this hypothesis.