Search results for "Examination"

Modifiable Lifestyle Factors and Cognitive Function in Older People: A Cross-Sectional Observational Study

2019

Background: The development of evidence-based interventions for delaying or preventing cognitive impairment is an important challenge. Most previous studies using self-report questionnaires face problems with reliability and consistency due to recall bias or misclassification among older people. Therefore, objective measurement of lifestyle components is needed to confirm the relationships between lifestyle factors and cognitive function. Aims: The current study examined the relationship between lifestyle factors collected with wearable sensors and cognitive function among community-dwelling older people using machine learning. Methods: In total, 855 participants (mean age: 73.8 years) wore…

A population-based survey of cognitive performance in a Sicilian elderly community.

2010

<i>Background:</i> The global burden of neurodegenerative diseases is increasing. Previous studies reported differences related to age, gender and socioeconomic status. We calculated the cognitive performances of a Sicilian population aged 65 years or older, by means of a door-to-door population-based survey in Bagheria city, Sicily. <i>Methods:</i> A door-to-door survey was carried out in the city of Bagheria, Sicily (prevalence day September 30, 2006). A cohort of 2,200 persons was randomly stratified, obtaining a 25% sample of the whole population. Cognitive function was assessed by Mini Mental State Examination (MMSE). Percentile distributions by age, gender, edu…

Effects of comprehensive geriatric intervention on physical performance among people aged 75 years and over.

2012

Background and aims: We studied the effects of comprehensive geriatric assessment and multifactorial intervention on physical performance among older people. Methods: In a 3-year geriatric development project with an experimental design, 668 participants aged 75–98 were assigned to intervention (n=348) or control (n=320) groups. The intervention group received comprehensive geriatric assessment with an individually targeted intervention for 2 years. The outcome measures—performance in the Timed Up-and-Go (TUG), 10-meter walking and Berg Balance Scale tests 2 were gathered annually during the intervention and the 1-year follow-up after it. Results: With linear mixed models, over the 2-year i…

Validation of Doloplus-2 among nonverbal nursing home patients : an evaluation of Doloplus-2 in a clinical setting

2010

Published version of an article from the journal: BMC Geriatrics. Also available from the publisher: http://dx.doi.org/10.1186/1471-2318-10-9 BACKGROUND:Pain measurement in nonverbal older adults is best based on behavioural observation, e.g. using an observational measurement tool such as Doloplus-2. The purposes of this study were to examine the use of Doloplus-2 in a nonverbal nursing home population, and to evaluate its reliability and validity by comparing registered nurses' estimation of pain with Doloplus-2 scores.METHOD:In this cross-sectional study, Doloplus-2 was used to observe the pain behaviour of patients aged above 65 years who were unable to self-report their pain. Nurses al…

Low Hemoglobin Levels and the Onset of Cognitive Impairment in Older People: The PRO.V.A. Study

2016

Low hemoglobin (Hb) levels are attracting interest as a risk factor for cognitive impairment, but with contrasting evidence emerging from the current literature. The aim of our work was to investigate the relationship between baseline serum Hb levels and the incidence of cognitive impairment in older people over a follow-up of 4.4 years. Our study considered a sample of 1227 elderly subjects cognitively intact at baseline, enrolled under the Progetto Veneto Anziani (Pro.V.A.) among 3099 screened subjects. For all participants, we measured serum Hb levels on blood samples; incident cognitive impairment was defined as a Mini Mental State Examination (MMSE) score <24 and confirmed by geriat…

2017

Purpose To analyze the effect of birth weight on ocular morphology, refraction and visual function in early adolescents aged 12–15 years. Material and methods We conducted a secondary data analysis using the public use files from the National Health and Nutrition Examination Survey of the period from 1999 to 2008. Study participants aged 12 to 15 years were included with data on birth weight and ophthalmic parameters including presenting distance visual acuity, objective refraction and keratometry. Visual acuity, sphere, astigmatism in power vectors J0 and J45, corneal power and corneal astigmatism were evaluated for an association with birth weight. Linear and logistic regression with adju…

Impact of missing data mechanism on the estimate of change: a case study on cognitive function and polypharmacy among older persons

2015

Piia Lavikainen,1,2 Esko Leskinen,3 Sirpa Hartikainen,1,2 Jyrki Möttönen,4 Raimo Sulkava,5 Maarit J Korhonen6 1Kuopio Research Centre of Geriatric Care, University of Eastern Finland, Kuopio, Finland; 2School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland; 3Department of Mathematics and Statistics, University of Jyväskylä, Jyväskylä, Finland; 4Department of Social Research, University of Helsinki, Helsinki, Finland; 5Department of Geriatrics, Institute of Public Health and Clinical Nutrition, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland; 6Department of Pharmacology, D…

Optimizing prostate cancer screening; prospective randomized controlled study of the role of PSA and PCA3 testing in a sequential manner in an opport…

2014

Abstract Objectives To reduce unnecessary biopsies (Bx) in an opportunistic screening programme of prostate cancer. Material and methods We performed a prospective evaluation of PCA3 as a second-line biomarker in an opportunistic screening for prostate cancer (PCa). From September 2010 until September 2012, 2,366 men, aged 40–74 years and with >10 years life expectancy, were initially screened with PSA/digital rectal examination (DRE). Men with previous Bx or with recent urine infections were excluded. Men with abnormal DRE and/or PSA > 3 ng/ml were submitted for PCA3. All men with PCA3 ≥ 35 underwent an initial biopsy (IBx) —12cores—. Men with PCA3   .5 ng/ml at 4-6months or PSAv > .75 ng/…

Prevalence of Levator Ani Defects in Urogynecological Patients

2016

Introduction: Defects of the levator ani muscle complex could represent a pathophysiological link between vaginal birth trauma and urogynecological symptoms many years later. The aim of our study was to determine the prevalence of levator ani muscle defects using 3D or 4D ultrasound and palpation in urogynecological patients. Material and Methods: Urogynecological patients were retrospectively investigated using 3D or 4D ultrasound. Clinical examination consisted of palpation and 3D or 4D imaging of the levator ani muscle. Results: A total of 319 women were included in the analysis. Mean age was 64.9 years, average parity was 2.1. Stress incontinence was present in 50.8 %, overactive bladde…

Sind wir wirklich so glücklich, wie wir es glauben? Eine kritische Untersuchung der Arbeitszufriedenheit an einer Universitätskinderklinik

2017

Zusammenfassung Ziel der Studie Trotz zahlreich berichteter Defizite und einem zunehmend angespannten Arbeitsumfeld in deutschen Krankenhäusern wird die Arbeitszufriedenheit von den Mitarbeitern regelmäßig als hoch bis sehr hoch einschätzt. Damit fehlen wichtige Argumente zur nachhaltigen Verbesserung von Arbeitsbedingungen gegenüber den Vorständen. Aus dieser Diskrepanz zwischen Arbeitsbedingungen und subjektiver Zufriedenheit ergab sich die Motivation für die vorliegende Arbeit. Methodik Die Datenerhebung erfolgte mittels einer Mitarbeiterbefragung am Kinderzentrum des Universitätsklinikum Leipzig AöR. Unterteilt wurde nach ärztlichem, Pflege- und Funktionsdienst. Gemessen wurde die subje…