Search results for "Examination"

showing 10 items of 563 documents

Extreme thrombocytosis as a sign of coeliac disease in the elderly: case report

2002

Increase in the number of blood platelets to over 1 000 000/mm 3 in elderly patients is generally considered secondary to a myeloproliferative or neoplastic disease. To report the case of an elderly woman hospitalized for extreme thrombocytosis associated with severe anaemia, who was found to be suffering from coeliac disease. The patient, aged 83 years, was hospitalized presenting with fatigue. Laboratory tests showed microcytic hypochromic anaemia (haemoglobin 4 g/dl) and extreme thrombocytosis (platelet count 1 400 000/mm 3 ). Physical examination was normal, with the exception of marked thinness. There was no evidence of macroscopic bleeding from the gastrointestinal or genitourinary tr…

Pathologymedicine.medical_specialtySettore MED/09 - Medicina InternaAtrophic gastritisPhysical examinationRisk AssessmentSeverity of Illness IndexCoeliac diseaseDiagnosis DifferentialHumanscoeliac disease thrombocytosis iron-deficiency anaemia elderlyMedicineIntestinal MucosaAgedAged 80 and overThrombocytosisLamina propriaHepatologymedicine.diagnostic_testThrombocytosisPlatelet Countbusiness.industryGastroenterologyPrognosismedicine.diseaseCeliac Diseasemedicine.anatomical_structureIron-deficiency anemiaSerum ironAbdomenFemalebusinessEuropean Journal of Gastroenterology & Hepatology
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Papulo-purpuric dermatitis of childhood: a distinct PLEVA-like eruption associated to SARS-CoV-2 infection. Clinical, histopathological and immunohis…

2021

Abstract We observed ten children with a papular eruption with purpuric features during the SARS‐CoV‐2 pandemic in Northern Italy (May‐December 2020). Histological examination showed signs of SARS‐CoV‐2‐related dermatosis. Evidence of nucleocapsid viral proteins using SARS‐CoV‐2 (2019‐nCoV) nucleocapsid antibody revealed cuticular staining of the deep portion of the eccrine glands in all cases.

Pathologymedicine.medical_specialtySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)virusesdermatopathology pediatric PLEVA SARS-CoV-2 skin histopathology Humans Pandemics SARS-CoV-2 COVID-19 Dermatitis PurpuraDermatitisDermatologySARS‐CoV‐2Eccrine glandMedicineHumansskin and connective tissue diseasesdermatopathologyPandemicsPurpuraHistological examinationbiologybusiness.industrySARS-CoV-2fungiskin histopathologyCOVID-19Original ArticlesNorthern italyStainingrespiratory tract diseasesbody regionspediatricPLEVAPediatrics Perinatology and Child Healthbiology.proteinImmunohistochemistryOriginal ArticleDermatopathologyAntibodybusiness
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Prognostic Role of CSF β-amyloid 1–42/1–40 Ratio in Patients Affected by Amyotrophic Lateral Sclerosis

2021

The involvement of β-amyloid (Aβ) in the pathogenesis of amyotrophic lateral sclerosis (ALS) has been widely discussed and its role in the disease is still a matter of debate. Aβ accumulates in the cortex and the anterior horn neurons of ALS patients and seems to affect their survival. To clarify the role of cerebrospinal fluid (CSF) Aβ 1–42 and Aβ 42/40 ratios as a potential prognostic biomarker for ALS, we performed a retrospective observational study on a cohort of ALS patients who underwent a lumbar puncture at the time of the diagnosis. CSF Aβ 1–40 and Aβ 1–42 ratios were detected by chemiluminescence immunoassay and their values were correlated with clinical features. We found a signi…

Pathologymedicine.medical_specialtybeta amyloidArticlelcsh:RC321-571Pathogenesis03 medical and health sciences0302 clinical medicineCerebrospinal fluidmedicineAmyotrophic lateral sclerosislcsh:Neurosciences. Biological psychiatry. Neuropsychiatry030304 developmental biology0303 health sciencesMini–Mental State Examinationmedicine.diagnostic_testLumbar puncturebusiness.industryGeneral Neurosciencebiomarker.Retrospective cohort studymedicine.diseaseCortex (botany)Biomarker (medicine)biomarkerALSbusiness030217 neurology & neurosurgeryBrain Sciences
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Ultrasonic demonstration of small pancreatic islet cell tumors.

1982

In three patients real-time sonography successfully localized small pancreatic islet cell tumors measuring 7, 8, and 17 mm in size. Ultrasound is suggested as the initial radiologic examination for localization of endocrine pancreatic tumors. If ultrasound is negative or equivocal, computerized tomography, arteriography, and pancreatic venous sampling are indicated.

Pathologymedicine.medical_specialtybusiness.industryRadiologic examinationUltrasoundMiddle Agedmedicine.diseaseAdenoma Islet CellPancreatic venous samplingPancreatic Neoplasmsmedicine.anatomical_structureEndocrinologyInternal medicinePancreatic islet cell tumorsMedicineHumansRadiology Nuclear Medicine and imagingUltrasonic sensorFemaleInsulinomaEndocrine pancreatic tumorsbusinessPancreasInsulinomaUltrasonographyJournal of clinical ultrasound : JCU
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Teksta autentiskums lasīšanas pārbaudes darbos

2016

Diplomdarbā ir iztirzāts valsts eksāmena 12. klasēm angļu valodā lasīšanas daļas tekstu autentiskums. Pētījuma mērķis ir izpētīt lasīšanas daļas tekstus un apkopot pierādījumus gan situatīvajam autentiskumam, gan interaktīvajam autentiskumam. Tēmas aktualitāti nosaka tas fakts, ka autentiskums ir viena no svarīgākajām komunikatīvo valodas pārbaudes darbu īpatnībām. Diplomdarbā ir apskatīts autentiskums un tā svarīgums lasīšanas pārbaudes darbos. Tā kā tekstu autentiskums ir cieši saistīts ar uzdevumu autentiskumu un kārtotāju autentiskumu, visiem šiem veidiem tika pievērsta uzmanība sakopojot pierādījumus gan situatīvajam, gan interaktīvajam autentiskumam. Teorētiskās pamatotības pierādījum…

Pedagoģijareading test of year 12 English examinationsituational authenticityinteractioanal authenticitytext authenticity
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Oropharyngeal dysphagia in elderly population suffering from mild cognitive impairment and mild dementia: Understanding the link

2020

Abstract Purpose To evaluate the prevalence of oropharyngeal dysphagia in elderly patients suffering from minimal or mild cognitive decline. Patients and methods We retrospectively collected the data of patients suffering from mild cognitive impairment or mild dementia and were undergoing management for suspected oropharyngeal dysphagia, in our department. All our patients were subjected to Mini Mental State Examination test, MD Anderson dysphagia inventory and caregiver mealtime and dysphagia questionnaire. We performed a mealtime observation study and endoscopic evaluation of swallowing in all our patients. Following evaluation, we then analysed the data statistically. Results Out of 708 …

Pediatricsmedicine.medical_specialtyFEESComorbidity03 medical and health sciences0302 clinical medicineSwallowingAlzheimer Diseaseotorhinolaryngologic diseasesmedicineHumansCognitive DysfunctionCognitive decline030223 otorhinolaryngologyCognitive impairmentMD Anderson Dysphagia InventoryAgedRetrospective StudiesAged 80 and overMini–Mental State Examinationmedicine.diagnostic_testbusiness.industryDysphagiaSwallowingAlzheimer'sDysphagiaDeglutitionCognitive impairmentOtorhinolaryngology030220 oncology & carcinogenesisMild dementiaDementiamedicine.symptomDeglutition DisordersbusinessOropharyngeal dysphagiaAmerican Journal of Otolaryngology
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Extensive Antibiotic and Antimalarial Prescription Rate among Children with Acute Febrile Diseases in the Lake Victoria Region, Tanzania

2021

Abstract Objectives Acute mosquito-borne febrile diseases pose a threat to children in the Sub-Saharan-Africa with ∼272 000 children dying worldwide from malaria in 2018. Although the awareness for malaria in this area has increased due to improved health education, the apparent decline of actual malaria cases has not affected clinical practice significantly. This study collected clinical and epidemiologic data of children presenting with acute febrile diseases in order delineate their diagnostic and therapeutic management. Methods A hospital-based cross-sectional clinical study was conducted at the Sekou Toure Regional Referral Hospital in Tanzania. Children between 1 month and 12 years of…

Pediatricsmedicine.medical_specialtyReferral030231 tropical medicinePhysical examinationTanzaniaAntimalarials03 medical and health sciences0302 clinical medicineHealth caremedicineAnimalsHumansOutpatient clinic030212 general & internal medicineMedical prescriptionChildbiologymedicine.diagnostic_testbusiness.industryInfantmedicine.diseasebiology.organism_classificationAnti-Bacterial AgentsLakesCross-Sectional StudiesPrescriptionsInfectious DiseasesTanzaniaPediatrics Perinatology and Child HealthHealth educationbusinessMalariaJournal of Tropical Pediatrics
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Prevalence of cardiovascular late sequelae in long-term survivors of childhood cancer: A systematic review and meta-analysis

2017

Background Cardiovascular diseases are well-known late effects of childhood cancer and research on these late effects is a highly important emerging field. We conducted a systematic review with a meta-analysis to give an overview of the current evidence and the prevalence of late cardiovascular events. Procedure We included publications in which the study populations were children and adolescents who survived cancer. Outcome was defined as all cardiovascular clinical and subclinical endpoints or diagnoses appearing at least one year after cancer diagnosis. A systematic overview is presented for all included studies. A quantitative meta-analysis was conducted for hypertension and stroke. Res…

Pediatricsmedicine.medical_specialtybusiness.industryChildhood cancerCancer therapyCancerHematology030204 cardiovascular system & hematologymedicine.diseaseExamination method03 medical and health sciences0302 clinical medicineOncology030220 oncology & carcinogenesisMeta-analysisPediatrics Perinatology and Child HealthmedicinePhysical therapyMedical diagnosisbusinessStrokeSubclinical infectionPediatric Blood & Cancer
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Wilms tumours diagnosed by routine physical examinations.

1988

Sir: The prognosis of stage I and -II Wilms tumours with favourable histology is good, reaching 97% (stage I) and 92% (stage II) 5 year disease-free survival rates [1]. With these figures in mind the question arises whether the overall prognosis of Wilms tumours could be improved by presymptomatic routine physical examinations in an attempt to avoid stage III to V primary diagnoses. In the Federal Republic of Germany six routine physical examinations (RPE) are offered to infants, and two additional ones to children between 12 and 48 months. The 1980-1987 German Wilms tumour study [1] listed 313 patients, 29 of whom (9%) were diagnosed by such routine examinations. As shown in Table 1, the R…

Pediatricsmedicine.medical_specialtybusiness.industryWilms tumourFederal republic of germanyInfantStage iiWilms TumorKidney NeoplasmsChild PreschoolPediatrics Perinatology and Child HealthmedicinePhysical therapyHumansStage (cooking)Detection ratebusinessPhysical ExaminationEuropean journal of pediatrics
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Ocular Motor Paroxysmal Events in Neonates and Infants: A Review of the Literature

2021

Abstract Background Ocular paroxysmal events can accompany a variety of neurological disorders. Particularly in infants, ocular paroxysmal events often represent a diagnostic challenge. Distinguishing between epileptic and nonepileptic events or between physiological and pathologic paroxysmal events can be challenging at this age because the clinical evaluation and physical examination are often limited. Continuous polygraphic video-electroencephalography (EEG) monitoring can be helpful in these situations. Methods We review ocular paroxysmal events in newborns and infants. The aim is to improve clinical recognition of ocular paroxysmal events and provide a guide to further management. Usin…

Pediatricsmedicine.medical_specialtygenetic structuresOcular motorSocio-culturaleEpileptic phenomenaPhysical examinationNystagmusElectroencephalographyOpsoclonus.NystagmuDiagnosis DifferentialNystagmus03 medical and health sciencesEpileptic phenomena; Newborn; Nonepileptic phenomena; Nystagmus; Opsoclonus0302 clinical medicineOcular Motility DisordersDevelopmental NeuroscienceNeuroimaging030225 pediatricsmedicineHumansNonepileptic phenomenaEpilepsymedicine.diagnostic_testbusiness.industryInfant NewbornInfantMultimodal therapyElectroencephalographyOpsoclonusNewborneye diseasesNeurologyPediatrics Perinatology and Child HealthEtiologyNeurology (clinical)medicine.symptombusinessClinical evaluation030217 neurology & neurosurgery
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