Search results for "Excess"
showing 10 items of 225 documents
Mathematical modelling of social obesity epidemic in the region of Valencia, Spain
2010
In this article, we analyse the incidence of excess weight in 24- to 65-year-old residents in the region of Valencia, Spain, and predict its behaviour in the coming years. In addition, we present some possible strategies to prevent the spread of the obesity epidemic. We use classical logistic regression analysis to find out that a sedentary lifestyle and unhealthy nutritional habits are the most important causes of obesity in the 24- to 65-year-old population in Valencia. We propose a new mathematical model of epidemiological type to predict the incidence of excess weight in this population in the coming years. Based on the mathematical model sensitivity analysis, some possible general stra…
Stereoselective Synthesis and Pharmacological Evaluation of 2,4-Bridged Piperidine Derivatives Designed to Activate the κ-Opioid Receptor
2021
Hypersonnia in children affected by migraine whitout aura: a questionnaire-based case-control study
2013
Proposal and validation of a novel quantitative approach (QUEM) for the evaluation of menstrual blood losses. Preliminary implementation for the mana…
2010
Menorrhagiaisaveryprevalentbleedingsymptomincongenitalbleedingdisorders(from60to100%)and in patients on OralAnticoagulants(OA),but no prospective studies are available. We here describe the validation of a new and simple method for determination of menstrual blòood losses
Asymmetric Synthesis of Fluorinated Isoindolinones through Palladium-Catalyzed Carbonylative Amination of Enantioenriched Benzylic Carbamates
2015
The asymmetric synthesis of fluorinated isoindolinones has been achieved by a palladium-catalyzed aminocarbonylation reaction of the corresponding -fluoroalkyl o-iodobenzylamines. A base-mediated anti -hydride elimination process was suggested to explain the partial erosion of the optical purity observed in some cases. This mechanistic rationale enabled the minimization of this partial racemization by fine-tuning the pK(a) of the base.
Review of Particle Physics
2020
The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 2,143 new measurements from 709 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as supersymmetric particles, heavy bosons, axions, dark photons, etc. Particle properties and search limits are listed in Summary Tables. We give numerous tables, figures, formulae, and reviews of topics such as Higgs Boson Physics, Supersymmetry, Grand Unified Theories, Neutrino Mixing, Dark Energy, Dark Matter, Cosmology, Particle Detectors, Colliders, …
A model of dunnian flow at hillslope scale
2005
The development of a thin stream above the soil surface (overland flow) is associated to two mechanism of runoff generation on the hillslope: the infiltration excess (hortonian flow) and saturation excess (dunnian flow) mechanism. The first one is typical of arid and semi-arid regions, usually characterised by high rainfall intensities on soil exhibiting low permeability. The second one, firstly introduced by Hewlett and Hibbert, constitutes the main mechanism of runoff generation in humid regions, characterised by high groundwater table. In the last mechanism runoff is produced by contributing areas of restricted extent that expands with time, where near to the bottom of the hillslope a hi…
Epidemiology, diagnosis and management of hirsutism: a consensus statement by the Androgen Excess and Polycystic Ovary Syndrome Society.
2012
Background Hirsutism, defined by the presence of excessive terminal hair in androgen-sensitive areas of the female body, is one of the most common disorders in women during reproductive age. Methods We conducted a systematic review and critical assessment of the available evidence pertaining to the epidemiology, pathophysiology, diagnosis and management of hirsutism. Results The prevalence of hirsutism is ~10% in most populations, with the important exception of Far-East Asian women who present hirsutism less frequently. Although usually caused by relatively benign functional conditions, with the polycystic ovary syndrome leading the list of the most frequent etiologies, hirsutism may be th…
From Overstoichiometric to Substoichiometric Enantioselective Protonation with 2-Sulfinyl Alcohols: A View in Perspective
2005
A general study of the enantioselective protonation of prochiral enolates with 2-sulfinyl alcohols is reported. The modification of reaction conditions to reduce drastically the amount of chiral proton source needed to obtain a good enantiomeric excess is reported. The effects of the different factors controlling the stereoselectivity are clearly established. Different protocols for enolate generation are compared.
Lipase-catalyzed resolution of β-hydroxy selenides
2006
Abstract Eleven β-hydroxy selenides were kinetically resolved using an immobilized lipase (Amano PS-C II) in toluene in the presence of vinyl acetate at 30 °C. This approach provided, in several cases, both enantiomers in high enantiomeric excess. The role of the size of substituents and the behaviour of cyclic β-hydroxy selenides is also discussed. Enantiopure β-hydroxy selenides are useful building blocks. As an application of this chemistry, enantiopure (1 S ,2 R )-indene oxide was obtained in one step from the proper enantiopure β-hydroxy selenide.