Search results for "Exercise intensity"

showing 10 items of 46 documents

Exercise intensity and markers of inflammation during and after (neo-) adjuvant cancer treatment.

2021

Exercise training has been hypothesized to lower the inflammatory burden for patients with cancer, but the role of exercise intensity is unknown. To this end, we compared the effects of high-intensity (HI) and low-to-moderate intensity (LMI) exercise on markers of inflammation in patients with curable breast, prostate and colorectal cancer undergoing primary adjuvant cancer treatment in a secondary analysis of the Phys-Can randomized trial (NCT02473003). Sub-group analyses focused on patients with breast cancer undergoing chemotherapy. Patients performed 6 months of combined aerobic and resistance exercise on either HI or LMI during and after primary adjuvant cancer treatment. Plasma taken …

0301 basic medicineMaleCancer Researchmedicine.medical_specialtyColorectal cancerEndocrinology Diabetes and Metabolismmedicine.medical_treatmentBreast NeoplasmsGastroenterologylaw.invention03 medical and health sciences0302 clinical medicineEndocrinologyBreast cancerRandomized controlled triallawProstateInternal medicinemedicineHumansExerciseInflammationChemotherapybiologybusiness.industryC-reactive proteinCancermedicine.diseaseExercise Therapy030104 developmental biologymedicine.anatomical_structureOncology030220 oncology & carcinogenesisExercise intensitybiology.proteinFemalebusinessBiomarkersEndocrine-related cancer
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Expression Pattern of Angiogenic Factors in Healthy Heart in Response to Physical Exercise Intensity

2019

Recently, many studies showing the regeneration potential of both cardiac and hematopoietic stem cells in adult heart following injury were definitively retracted by the literature. Therefore, stimulating myocardial angiogenesis becomes to be important for preventing cardiovascular diseases. Regular endurance exercise has been reported to induce capillary growth in healthy and diseased myocardium resulting in cardioprotective phenotype. Previously, we demonstrated a significantly increased capillary proliferation in mouse hearts following 30 and 45 days of endurance training. In the present study, we examined the localization and expression pattern of vascular endothelial growth factor rece…

0301 basic medicinemedicine.medical_specialtyAngiogenesisPhysiologyPhysical exercisecapillary growthheart030204 cardiovascular system & hematologylcsh:Physiology03 medical and health sciencesParacrine signallingchemistry.chemical_compoundangiogenesis0302 clinical medicineexercise intensityendurance trainingEndurance trainingphysical exercisePhysiology (medical)Internal medicineMedicineskeletal muscleOriginal ResearchSettore M-EDF/02 - Metodi E Didattiche Delle Attivita' Sportivebiologylcsh:QP1-981business.industryhypoxiaHypoxia (medical)Vascular endothelial growth factorNitric oxide synthase030104 developmental biologyEndocrinologychemistryExercise intensitybiology.proteincardiovascular systemmedicine.symptomheart skeletal muscle endurance training angiogenesis physical exercise capillary growth hypoxia exercise intensitybusinessSettore M-EDF/01 - Metodi E Didattiche Delle Attivita' Motorie
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Physical Exercise and DNA Injury

2017

Regular, low-intensity physical activity is currently advocated for lowering the risk of developing many acute and especially chronic diseases. However, several lines of evidence attest that strenuous exercise may enhance inflammation and trigger the generation of free radical-mediated damage, thus overwhelming the undisputable benefits of regular, medium-intensity physical activity. Since reactive oxygen species are actively generated during high-intensity exercise, and these reactive compounds are known to impact DNA stability, we review here the current evidence about strenuous exercise and DNA injury. Despite the outcome of the various studies cannot be pooled due to considerable variat…

0301 basic medicinemedicine.medical_specialtybusiness.industryDNA damageStrenuous exercisePhysical activityPhysical exercise030229 sport sciences03 medical and health sciences030104 developmental biology0302 clinical medicinePhysical medicine and rehabilitationDNA stabilitymedicineExercise intensityExertionIntensive care medicinebusinessDNA injury
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2019

A poor preoperative functional capacity increases the perioperative risk. Therefore, a web-based exercise approach has been initiated for a careful supervision and individual support of patients during their perioperative cancer therapy. Here, we present the data of a 57-year-old patient, scheduled for esophagectomy. Beside a five-week neoadjuvant chemoradiotherapy (CRT), the patient performed 10 weeks of a web-based prehabilitation exercise training (preconditioning) and continued the exercise program for 14 weeks after surgery. The patient performed 42 of 44 recommended training sessions in the preconditioning period in his home environment. This corresponds to a mean of 131 (±38) min of …

0301 basic medicinemedicine.medical_specialtybusiness.industrymedicine.medical_treatmentPrehabilitationPerioperativeEsophageal cancermedicine.disease03 medical and health sciences030104 developmental biology0302 clinical medicineOncologyEsophagectomy030220 oncology & carcinogenesismedicineCarcinomaPhysical therapyExercise intensityWeb applicationbusinessNeoadjuvant therapyCase Reports in Oncology
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5 Effects Of Low-intensity Concentric Combined With Blood Flow Restriction On Achilles Tendon

2014

Introduction Weight training is a useful tool in order to achieve muscular hypertrophy. However, the American College of Sports Medicine (ACSM) recommends intensities of 70% of one repetition maximum (1-RM). Those intensities may not be suitable for everyone because of the high mechanical stresses placed upon the joints [Loenneke, 2012]. Nowadays, it is common to combine low-intensity exercise (20–30% 1-RM) with blood flow restriction (BFR) because of the beneficial effects in increased muscular strength, hypertrophy, localised endurance and cardiorespiratory endurance [Pope, 2013]. Despite there is not many papers about the beneficial of this training, it is know that the tendon suffers so…

Achilles tendonmedicine.medical_specialtySports medicineStrength trainingbusiness.industryPhysical Therapy Sports Therapy and RehabilitationGeneral MedicinePhysical strengthTendonmedicine.anatomical_structureOne-repetition maximummedicinePhysical therapyExercise intensityOrthopedics and Sports MedicinebusinessLeg pressBritish Journal of Sports Medicine
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Exercise Effects on Erythrocyte Deformability in Exercise-induced Arterial Hypoxemia

2014

Exercise-induced arterial hypoxemia (EIAH) is often found in endurance-trained subjects at high exercise intensity. The role of erythrocyte deformability (ED) in EIAH has been scarcely explored. We aimed to explore the role of erythrocyte properties and lactate accumulation in the response of ED in EIAH. ED was determined in 10 sedentary and in 16 trained subjects, both before and after a maximal incremental test, and after recovery, along with mean corpuscular volume (MCV) and red blood cell lactate concentrations. EIAH was found in 6 trained subjects (∆SaO2=-8.25±4.03%). Sedentary and non-EIAH trained subjects showed reduced ED after exercise, while no effect on ED was found in EIAH train…

AdultErythrocyte IndicesMalemedicine.medical_specialtyErythrocytesCell volumeArterial hypoxemiaPhysical Therapy Sports Therapy and RehabilitationErythrocyte DeformabilityInternal medicinemedicineHumansErythrocyte deformabilityOrthopedics and Sports MedicineLactic AcidExercise physiologyHypoxiaExerciseMean corpuscular volumemedicine.diagnostic_testbusiness.industryIncremental testOxygenHemoglobinometryExercise intensityCardiologyPhysical therapybusinessPerfusionInternational Journal of Sports Medicine
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The relation between cycling time to exhaustion and anaerobic threshold.

1990

This study investigated whether the anaerobic threshold (AnT) could be used to predict prolonged work capacity measured as cycling time to exhaustion (= endurance time) and which factors, in addition to relative exercise intensity, could explain variation in endurance time. Theoretical exercise intensities corresponding to certain endurance times were also calculated. The hyperbolic and exponential functions between cycling time and relative work rate (WR[%]), as well as between cycling time and relative oxygen uptake (VO2[%]) were fitted to the pooled data (n = 45) of 17 subjects. The WR(%) and VO2(%) were expressed as a percentage of the subject's own AnT- and maximum-values. At WR corres…

AdultMaleGlycogenAnaerobic ThresholdWork Capacity EvaluationPhysical Therapy Sports Therapy and RehabilitationHuman Factors and ErgonomicsWork rateMiddle AgedExponential functionchemistry.chemical_compoundAnimal scienceOxygen ConsumptionchemistryReference ValuesExercise intensityBlood lactateExercise TestPhysical EnduranceHumansCyclingAnaerobic exerciseSimulationTime to exhaustionErgonomics
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Reliability of different models to assess heart rate recovery after submaximal bicycle exercise.

2011

Abstract Objectives : Different models to assess HR recovery have been developed but knowledge of their reliability is poor at different submaximal exercise intensities and recovery durations. Our aim was to determine the reliability of HR recovery after a test on a cycle ergometer. Design : Twenty-one healthy individuals performed a submaximal exercise at 65% and 80% HR max followed by passive recovery. The exercise was repeated (retest) within 2 weeks to assess reliability. Method : HR recovery was assessed by 8 models, based on monoexponential kinetics or absolute recovery (recovered HR at fix time points). Intraclass correlation coefficient (ICC) and standard error of measurement (SEM, …

AdultMalemedicine.medical_specialtyAdolescentIntraclass correlationPassive recoveryPhysical Therapy Sports Therapy and RehabilitationSubmaximal exerciseModels BiologicalYoung AdultHeart RateInternal medicineHeart ratemedicineHumansOrthopedics and Sports MedicineExerciseReliability (statistics)SimulationExercise Tolerancebusiness.industryRepeatabilityRecovery of FunctionBicyclingStandard errorSpainCardiologyExercise intensityExercise TestLinear ModelsPhysical EnduranceFemalebusinessJournal of science and medicine in sport
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Plasma catecholamine and serum testosterone responses to four units of resistance exercise in young and adult male athletes.

1998

The plasma noradrenaline (NA) and adrenaline (A) concentration responses of seven young male athletes [15 (SD 1) years] and seven adult male athletes [25 (SD 6) years] were investigated together with the serum testosterone (Tes) concentration responses in four different half-squatting exercises. The loads, number of repetitions, exercise intensity and recovery between the sets were manipulated such that different types of metabolic demand could be expected. However, the amount of work done was kept equal in each kind of exercise. After the most exhausting unit of exercise (E3; two sets of 30 repetitions with 50% of 1 repetition maximum and with 2-min recovery between the sets) the plasma NA…

AdultMalemedicine.medical_specialtyAgingSympathetic Nervous SystemSports medicineAdolescentEpinephrineWeight LiftingPhysiologymedicine.drug_classPhysical exerciseNorepinephrineHeart RatePhysiology (medical)Internal medicinemedicineHumansOrthopedics and Sports MedicineTestosteroneLactic AcidExercise physiologyExerciseTestosteronebiologyAthletesbusiness.industryPublic Health Environmental and Occupational HealthGeneral Medicinebiology.organism_classificationAndrogenEndocrinologyMuscle FatigueCatecholamineExercise intensityExercise Testbusinessmedicine.drugEuropean journal of applied physiology and occupational physiology
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Effects of endurance exercise on serum concentration of calcitonin gene-related peptide (CGRP): A potential link between exercise intensity and heada…

2020

Abstract Background Calcitonin gene-related peptide (CGRP) is a powerful neuropeptide that is strongly involved in headache pain pathogenesis by triggering vasodilation, mast cell degranulation and neurogenic inflammation. This evidence has prompted us to investigate the acute influence of endurance exercise on CGRP concentration in blood. Methods The study population consisted of 48 male amateur runners, who ran a half-marathon distance at 75%–85% of maximal oxygen uptake. Blood was drawn before the run (pre-run) and immediately after each runner ended his trial (post-run). The serum concentration of CGRP was measured with a commercial enzyme-linked immunosorbent assay (ELISA) technique. R…

AdultMalemedicine.medical_specialtyAnti-calcitonin gene-related peptide agentsCalcitonin Gene-Related PeptideClinical BiochemistryVasodilationCalcitonin gene-related peptideRunning03 medical and health sciences0302 clinical medicineEndurance trainingInternal medicinemedicineHumansExerciseMigraineanti-calcitonin gene-related peptide agents ; headache ; migraine ; neuropeptide ; physical activity ; runningNeurogenic inflammationbusiness.industryPhysical activityBiochemistry (medical)HeadacheVO2 max030229 sport sciencesGeneral MedicineMiddle Agedmedicine.diseaseNeuropeptideEndocrinologyMigraineCalcitoninPhysical EnduranceExercise intensityAnti-calcitonin gene-related peptide agents; Headache; Migraine; Neuropeptide; Physical activity; Runningbusiness030217 neurology & neurosurgery
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