Search results for "Exercise"

showing 10 items of 3151 documents

Sestrins: Novel antioxidant and AMPK-modulating functions regulated by exercise?

2013

Oxidative stress results from damage to tissues caused by free radicals and is increased by exercise. Peroxiredoxins (PRXs) maintain the cellular reducing environment by scavenging intracellular hydrogen peroxide. It has been recently noted that physical exercise has a positive effect on the PRX system, exerting a protective effect against oxidative stress-induced damage. However, other compounds, such as sestrins (SESNs), a stress-inducible protein family with antioxidant properties, should also be considered in the function of PRXs. SESNs are clearly involved in the regeneration process of PRXs and therefore may also be modulated by physical exercise. In addition, SESNs are clearly involv…

medicine.medical_specialtyPhysiologyClinical BiochemistryNeurodegenerationAMPKPhysical exerciseCell BiologyOxidative phosphorylationBiologymedicine.diseasemedicine.disease_causeCell biologyInsulin resistanceEndocrinologySarcopeniaInternal medicinemedicineSignal transductionOxidative stressJournal of Cellular Physiology
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Antidepressant Effects of Exercise: A Role for the Adiponectin-PGC-1α-kynurenine Triad?

2015

It is well-recognized that exercise improves mental health, e.g., by decreasing depressive behaviors, improving hippocampal-dependent learning and neurogenesis, and increasing dendritic plasticity. Yet how exercise influences the brain at the molecular level is not clearly understood. Yau et al recently reported that the antidepressant effects of physical exercise are mainly mediated by adiponectin, an adipocyte-secreted hormone ('adipocytokine') with neuroprotective effects at the central nervous system level (Yau et al., 2014). 4.155 JCR (2015) Q1, 12/83 Physiology; Q2, 63/187 Cell biology UEM

medicine.medical_specialtyPhysiologyClinical BiochemistrySaludchemistry.chemical_compoundTriad (sociology)Internal medicinemedicineAnimalsHumansExercise physiologyMuscle SkeletalEducación físicaExerciseKynurenineAdiponectinbusiness.industryKynurenine metabolismCell BiologyEjercicio físicoEndocrinologychemistryAntidepressantAdiponectinbusinessKynurenineTranscription FactorsJournal of Cellular Physiology
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Corrected whole blood biomarkers - the equation of Dill and Costill revisited.

2018

Abstract An exercise bout or a dehydration often causes a reduction in plasma volume, which should be acknowledged when considering the change in biomarkers before and after the plasma changing event. The classic equation from Dill and Costill (1974, J. Appl. Physiol., 37, 247–248) for plasma volume shift is usually utilized in such a case. Although this works well with plasma and serum biomarkers, we argue in this note that this traditional approach gives misleading results in the context of whole blood biomarkers, such as lactate, white cells, and thrombocytes. In this study, we demonstrate that to calculate the change in the total amount of circulating whole blood biomarker, one should u…

medicine.medical_specialtyPhysiologyContext (language use)030204 cardiovascular system & hematologyPlasma volumeta311103 medical and health sciencesHemoglobins0302 clinical medicineSerum biomarkersPhysiology (medical)Internal medicineMembrane PhysiologymedicineHumansplasma changePlasma Volumeta315Exercisecorrection formulaWhole bloodOriginal ResearchDehydrationbusiness.industryEndurance and PerformanceDill and Costill equationveri030229 sport sciencesBiomarkerEndocrinologymarkkeritBiomarker (medicine)veriplasmaHemoglobinsense organsCellular PhysiologybusinessAlgorithmsBiomarkersPhysiological reports
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Changes induced by eccentric training on force-velocity relationships of the elbow flexor muscles.

1995

The aim of this study was to examine the effects of a short term eccentric training period on force-velocity relationships of the elbow flexor muscles. From a muscle model, the maximal shortening velocity Vo(x) and the af parameter which varies according to the curvature of the force-velocity relationship of the muscle were determined. Sixteen volunteer subjects divided into 2 groups participated in this study (Group Eccentric GE, n = 8; Group Control GC, n = 8). The subjects performed, on an isokinetic ergometer, 2 maximal concentric elbow flexions at different angular velocities (60, 120, 180, 240, 300, 360 degrees s-1) and held maximal and submaximal isometric actions at an elbow flexion…

medicine.medical_specialtyPhysiologyElbowIsometric exerciseElectromyographyConcentricBicepsModels BiologicalPhysical medicine and rehabilitationPhysiology (medical)Isometric ContractionmedicineElbowEccentricHumansOrthopedics and Sports MedicineExercisemedicine.diagnostic_testbusiness.industryElectromyographyMusclesPublic Health Environmental and Occupational HealthGeneral MedicineAnatomymusculoskeletal systemmedicine.anatomical_structureEccentric trainingUpper limbbusinessEuropean journal of applied physiology and occupational physiology
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Greater Strength Gains after Training with Accentuated Eccentric than Traditional Isoinertial Loads in Already Strength-Trained Men

2016

As training experience increases it becomes more challenging to induce further neuromuscular adaptation. Consequently, strength trainers seek alternative training methods in order to further increase strength and muscle mass. One method is to utilize accentuated eccentric loading, which applies a greater external load during the eccentric phase of the lift as compared to the concentric phase. Based upon this practice, the purpose of this study was to determine the effects of 10 weeks of accentuated eccentric loading vs. traditional isoinertial resistance training in strength-trained men. Young (22 ± 3 years, 177 ± 6 cm, 76 ± 10 kg, n = 28) strength-trained men (2.6 ± 2.2 years experience) w…

medicine.medical_specialtyPhysiologyIsometric exerciseConcentriclcsh:PhysiologyMuscle hypertrophy03 medical and health sciences0302 clinical medicinePhysiology (medical)Internal medicineCross-sectional areaMedicineEccentricta315Leg pressOriginal Researcheccentric-overloadlcsh:QP1-981business.industryWork (physics)Resistance trainingResistance Trainingvoluntary activationTwitch interpolationHypertrophy030229 sport sciencesM-wavecross-sectional areaCardiologyPhysical therapyresistance traininghypertrophybusiness030217 neurology & neurosurgeryFrontiers in Physiology
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Response of Bone Metabolism Markers to Ice Swimming in Regular Practitioners

2021

Objective: Both exercise and cold exposure cause physiological stress and they often occur in combination. However, the effects of exercise during severe cold on variation in bone metabolism in humans have remained elusive. The aim of this study was to investigate the variations in circulating bone metabolism markers after ice swimming (IS).Methods: Eighty-seven women and men aged 42–84 years old were recruited to perform regular IS activities. Serum parathyroid hormone (PTH), total calcium (Ca2+), total phosphorus (Pi), total magnesium (Mg2+), N-terminal osteocalcin (N-MID), total propeptide of procollagen 1 (TPINP), and C-terminal telopeptide of type 1 collagen (β-CTX) were measured 30 mi…

medicine.medical_specialtyPhysiologyOsteoporosiscold exposureParathyroid hormoneparathyroid hormone (PTH)bone (re)modeling markersBone remodelingHyperphosphatemiaN-terminal telopeptideInternal medicinePhysiology (medical)medicineQP1-981Femoral neckOriginal ResearchBone mineralbiologyexercisebusiness.industrymedicine.diseaseEndocrinologymedicine.anatomical_structureOsteocalcinbiology.proteinbusinessbone mineral densityFrontiers in Physiology
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Knee extension strength and walking speed in relation to quadriceps muscle composition and training in elderly women.

1994

Summary. Knee extension strength, walking speed, quadriceps muscle mass and composition of the muscle compartment were studied in 66 to 85-year-old female athletes and controls. Maximal voluntary knee extension force, force/body mass, extension torque, torque/body mass and walking speed were higher for the athletes than the controls. A muscle index indicating intramuscular fat and connective tissue measured using ultrasonography was lower for the athletes than the controls. There were no differences between the study groups in knee extension force related either to cross-sectional area (CSA) or lean tissue area (CSAL) of the quadriceps. Within the subgroups, there was no significant correla…

medicine.medical_specialtyPhysiologyPhysical exerciseIsometric exerciseWalkingKnee extensionIsometric ContractionmedicineHumansKneeMuscle SkeletalAgedUltrasonographyAged 80 and overPhysical Education and TrainingbiologyAthletesbusiness.industryBody WeightQuadriceps muscleGeneral Medicinebiology.organism_classificationBody HeightPreferred walking speedAdipose TissuePhysical therapyBody CompositionFemaleIntramuscular fatUltrasonographybusinessTomography X-Ray Computedhuman activitiesClinical physiology (Oxford, England)
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Inter-individual different responses to continuous and interval training in recreational middle-aged women runners

2020

A crucial subject in sports is identifying the inter-individual variation in response to training, which would allow creating individualized pre-training schedules, improving runner’s performance. We aimed to analyze heterogeneity in individual responses to two half-marathon training programs differing in running volume and intensity in middle-aged recreational women. 20 women (40 ± 7 years, 61 ± 7 kg, 167 ± 6 cm, and VO2max = 48 ± 6 mL⋅kg–1⋅min–1) underwent either moderate-intensity continuous (MICT) or high-intensity interval (HIIT) 12-week training. They were evaluated before and after training with maximal incremental tests in the laboratory (VO2max) and in the field (time to exhaustion…

medicine.medical_specialtyPhysiologyRunners (Sports)responderhigh intensity interval trainingexercise and sportPhysical education and traininglcsh:PhysiologyInterval trainingmiddle-aged women03 medical and health sciences0302 clinical medicinePhysiology (medical)Dones esportistesMedicine030212 general & internal medicineTime to exhaustionlcsh:QP1-981business.industryWomen athletes030229 sport sciencesBrief Research ReportHIIT-High-intensity interval trainingShort intervalmoderate intense endurance exercise trainingCorredors (Esports)non-responderHomogeneoushalf-marathon runnersPhysical therapyEducació físicabusinessHigh-intensity interval training
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The metabolic syndrome in hypertension: European society of hypertension position statement.

2008

The metabolic syndrome considerably increases the risk of cardiovascular and renal events in hypertension. It has been associated with a wide range of classical and new cardiovascular risk factors as well as with early signs of subclinical cardiovascular and renal damage. Obesity and insulin resistance, beside a constellation of independent factors, which include molecules of hepatic, vascular, and immunologic origin with proinflammatory properties, have been implicated in the pathogenesis. The close relationships among the different components of the syndrome and their associated disturbances make it difficult to understand what the underlying causes and consequences are. At each of these …

medicine.medical_specialtyPhysiologySodium Chloride Symporter InhibitorsAdrenergic beta-AntagonistsPhysical exerciseAngiotensin-Converting Enzyme InhibitorsType 2 diabetesBioinformaticsInsulin resistanceWeight lossInternal medicineInternal MedicinemedicineHumansThiazideAntihypertensive AgentsMetabolic Syndromebusiness.industrymedicine.diseaseCalcium Channel BlockersObesityExercise TherapyEndocrinologyBlood pressureHypertensionmedicine.symptomMetabolic syndromeCardiology and Cardiovascular MedicinebusinessAngiotensin II Type 1 Receptor BlockersRisk Reduction Behaviormedicine.drugDiet TherapyJournal of hypertension
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Cardiorespiratory Coordination after Training and Detraining. A Principal Component Analysis Approach

2016

Our purpose was to study the effects of different training modalities and detraining on cardiorespiratory coordination (CRC). Thirty-two young males were randomly assigned to four training groups: aerobic (AT), resistance (RT), aerobic plus resistance (AT + RT), and control (C). They were assessed before training, after training (6 weeks) and after detraining (3 weeks) by means of a graded maximal test. A principal component (PC) analysis of selected cardiovascular and cardiorespiratory variables was performed to evaluate CRC. The first PC (PC1) coefficient of congruence in the three conditions (before training, after training and after detraining) was compared between groups. Two PCs were …

medicine.medical_specialtyPhysiologySpeech recognitioneducationphysiological variableslcsh:PhysiologyMalalties de l'aparell respiratori03 medical and health sciences0302 clinical medicinePhysiology (medical)MedicineCardiorespiratory exercise testingTraining programmeYoung maleOriginal Researchcomplex adaptive systemsTraining periodPrincipal Component AnalysisCoordinative variableslcsh:QP1-981business.industryCardiorespiratory fitnessRespiratory organs diseases030229 sport sciencesStrength variablesPrincipal component analysisPhysical therapybusiness030217 neurology & neurosurgerytraining effects
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