Search results for "Experimental"
showing 10 items of 18236 documents
Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity
2014
Objective: Environmental conditions (eg, latitude) play a critical role in the susceptibility and severity of many autoimmune disorders, including multiple sclerosis (MS). Here, we investigated the mechanisms underlying the beneficial effects of immune regulatory processes induced in the skin by moderate ultraviolet B (UVB) radiation on central nervous system (CNS) autoimmunity. Methods: Effects of UVB light were analyzed in a murine model of CNS autoimmunity (experimental autoimmune encephalomyelitis). Additionally, patients with relapsing–remitting MS were treated with narrowband UVB phototherapy. Immunomodulatory effects were examined in skin biopsies, serum samples, and immune cells of …
La emergencia viral como consecuencia de la interacción entre las variabilidades genéticas del virus y huésped
2015
La variabilidad genética en las poblaciones de huéspedes para la susceptibilidad al patógeno es esencial para la propagación de un virus emergente. Los modelos matemáticos predicen que la tasa de difusión del patógeno se frena a medida que aumenta la frecuencia y la diversidad de alelos de resistencia en la población huésped148,230. Sin embargo, las pruebas experimentales de esta hipótesis son escasas. Por ese motivo, este trabajo aborda la cuestión de cuánta heterogeneidad genética del huésped es necesaria para el cambio del destino evolutivo del virus. El modelo de patosistema experimental utilizado en este trabajo está compuesto por el Virus del grabado del tabaco (TEV), aislado At17b (T…
Measurement of Atmospheric Neutrino Oscillations at 6–56 GeV with IceCube DeepCore
2018
We present a measurement of the atmospheric neutrino oscillation parameters using three years of data from the IceCube Neutrino Observatory. The DeepCore infill array in the center of IceCube enables the detection and reconstruction of neutrinos produced by the interaction of cosmic rays in Earth's atmosphere at energies as low as ∼5 GeV. That energy threshold permits measurements of muon neutrino disappearance, over a range of baselines up to the diameter of the Earth, probing the same range of L/Eν as long-baseline experiments but with substantially higher-energy neutrinos. This analysis uses neutrinos from the full sky with reconstructed energies from 5.6 to 56 GeV. We measure Δm322=2.31…
Testing effects of Lorentz invariance violation in the propagation of astroparticles with the Pierre Auger Observatory
2021
The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargüe. We are very grateful to the following agencies and organizations for financial support: Argentina — Comisión Nacional de Energía Atómica; Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT); Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET); Gobierno de la Provincia de Mendoza; Municipalidad de Malargüe; NDM Holdings and Valle Las Leñas; in gratitude for their continuing cooperation over land access; Australia — the Australian Research Council; Be…
Monitoring and data quality assessment of the ATLAS liquid argon calorimeter
2014
The liquid argon calorimeter is a key component of the ATLAS detector installed at the CERN Large Hadron Collider. The primary purpose of this calorimeter is the measurement of electron and photon kinematic properties. It also provides a crucial input for measuring jets and missing transverse momentum. An advanced data monitoring procedure was designed to quickly identify issues that would affect detector performance and ensure that only the best quality data are used for physics analysis. This article presents the validation procedure developed during the 2011 and 2012 LHC data-taking periods, in which more than 98% of the proton-proton luminosity recorded by ATLAS at a centre-of-mass ener…
Exclusive measurement of quasi-free η-photoproduction from deuterium
2003
Quasi-free photoproduction of eta-mesons from the deuteron has been measured at the tagged photon facility of the Mainz microtron MAMI with the photon spectrometer TAPS for incident photon energies from the production threshold at 630 MeV up to 820 MeV. In a fully exclusive measurement eta-mesons and recoil nucleons were detected in coincidence. At incident photon energies above the production threshold on the free nucleon, where final state interaction effects are negligible, an almost constant ratio of sigma(n)/sigma(p)=0.66+/-0.10 was found. At lower incident photon energies the ratio rises due to re-scattering effects. The average ratio agrees with the value extracted from a comparison …
Action-Depicting Gestures and Morphosyntax: The Function of Gesture-Speech Alignment in the Conversational Turn
2021
The current study examines the role of action-depicting gestures in conversational turns by focusing on their semantic characteristics and temporal position in relation to their verbal affiliates (action verbs or more complex verb phrases). The data are video recordings of naturally occurring interactions in multilingual construction sites in Norway. The analysis distinguishes two modes of action depiction: generic depictions, which represent the action as a general type, and contextualized depictions, which in addition include deictic references to the spatio-material environment or iconic representations of the specific manner of action performance. These two modes typically occupy differ…
Measurement of the Fluctuations in the Number of Muons in Extensive Air Showers with the Pierre Auger Observatory
2021
The successful installation, commissioning, and operation of the Pierre Auger Observatory would not have been possible without the strong commitment and effort from the technical and administrative staff in Malargue. We are very grateful to the following agencies and organizations for financial support: Argentina-Comision Nacional de Energia Atomica, Agencia Nacional de Promocion Cientifica y Tecnologica (ANPCyT), Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Gobierno de la Provincia de Mendoza, Municipalidad de Malargue, NDM Holdings and Valle Las Lenas; in gratitude for their continuing cooperation over land access; Australia-the Australian Research Council; Brazil…
An ACT-R Based Humanoid Social Robot to Manage Storytelling Activities
2020
This paper describes an interactive storytelling system, accessible through the SoftBank robotic platforms NAO and Pepper. The main contribution consists of the interpretation of the story characters by humanoid robots, obtained through the definition of appropriate cognitive models, relying on the ACT-R cognitive architecture. The reasoning processes leading to the story evolution are based on the represented knowledge and the suggestions of the listener in critical points of the story. They are disclosed during the narration, to make clear the dynamics of the story and the feelings of the characters. We analyzed the impact of such externalization of the internal status of the characters t…
Beyond the Educational Context: Relevance of Intrinsic Reading Motivation During COVID-19 Confinement in Spain
2021
What role could have intrinsic motivation toward reading in an extraordinary situation like the recent confinement? This research examines the relationship between intrinsic reading motivation (IRM) and reading habits in an adult population considering types of reading (for leisure, work/study, social networks, and news), gender, and distress generated by the coronavirus disease 2019 (COVID-19) pandemic. Participants were 3,849 adults from Spain who were surveyed about their reading practices: before, during the first weeks, and after several weeks of confinement. Linear mixed effects models (LMMs) were used to analyze data. Results showed a three-way interaction between reading frequency, …