Search results for "Extension"
showing 10 items of 534 documents
Character correspondences in blocks with normal defect groups
2014
Abstract In this paper we give an extension of the Glauberman correspondence to certain characters of blocks with normal defect groups.
A bicistronic vector backbone for rapid seamless cloning and chimerization of αβT-cell receptor sequences.
2020
To facilitate preclinical testing of T-cell receptors (TCRs) derived from tumor-reactive T-cell clones it is necessary to develop convenient and rapid cloning strategies for the generation of TCR expression constructs. Herein, we describe a pDONR™221 vector backbone allowing to generate Gateway™ compatible entry clones encoding optimized bicistronic αβTCR constructs. It harbors P2A-linked TCR constant regions and head-to-head-oriented recognition sites of the Type IIS restriction enzymes BsmBI and BsaI for seamless cloning of the TCRα and TCRβ V(D)J regions, respectively. Additional well-established TCR optimizations were incorporated to enhance TCR functionality. This included replacing of…
La Méthode como hermenéutica musical Homenaje a Edgar Morin por su 100º cumpleaños
2021
The present work addresses the principles and properties of the complex thought formulated by the French thinker Edgar Morin and the way in which he was able me to articulate his conception of organizational complexity with one of the most important theories of musical analysis, which emerged at the beginning of the 20th century: the schenkerian analysis. It is a review and extension of a few pages of my doctoral thesis, which are intended to pay tribute to who has been, in addition to my teacher, Honorary President of Itamar since its first issue. His teachings and support has always been the engine for my quest for musical organization. On July 21, 2021, Morin celebrated his 100th birthda…
Are There Essentially Incomplete Knowledge Representation Systems?
2001
A mathematical model of a knowledge representation system (KR-system) is proposed. Its prototype is the concept of an information system in the sense of Z. Pawlak; however, the model is, in fact, a substantial extension of the latter. In our model, attributes may form an arbitrary category, where morphisms represent built-in functional dependencies, and uncertainty of knowledge is treated in terms of category theory via monads. Several notions of simulation are also considered for such KR-systems. In this general setting, the semiphilosophical problem mentioned in the title, still open, is given a precise meaning.
Morrey–Sobolev Extension Domains
2017
We show that every uniform domain of R n with n ≥ 2 is a Morrey-Sobolev W 1, p-extension domain for all p ∈ [1, n), and moreover, that this result is essentially best possible for each p ∈ [1, n) in the sense that, given a simply connected planar domain or a domain of R n with n ≥ 3 that is quasiconformal equivalent to a uniform domain, if it is a W 1, p-extension domain, then it must be uniform. peerReviewed
An integrated architecture for speech-input multi-target machine translation
2007
The aim of this work is to show the ability of finite-state transducers to simultaneously translate speech into multiple languages. Our proposal deals with an extension of stochastic finite-state transducers that can produce more than one output at the same time. These kind of devices offer great versatility for the integration with other finite-state devices such as acoustic models in order to produce a speech translation system. This proposal has been evaluated in a practical situation, and its results have been compared with those obtained using a standard mono-target speech transducer.
Speech-input multi-target machine translation
2007
In order to simultaneously translate speech into multiple languages an extension of stochastic finite-state transducers is proposed. In this approach the speech translation model consists of a single network where acoustic models (in the input) and the multilingual model (in the output) are embedded. The multi-target model has been evaluated in a practical situation, and the results have been compared with those obtained using several mono-target models. Experimental results show that the multi-target one requires less amount of memory. In addition, a single decoding is enough to get the speech translated into multiple languages.
A New Combinatorial Approach to Sequence Comparison
2008
In this paper we introduce a new alignment-free method for comparing sequences which is combinatorial by nature and does not use any compressor nor any information-theoretic notion. Such a method is based on an extension of the Burrows-Wheeler Transform, a transformation widely used in the context of Data Compression. The new extended transformation takes as input a multiset of sequences and produces as output a string obtained by a suitable rearrangement of the characters of all the input sequences. By using such a transformation we give a general method for comparing sequences that takes into account how much the characters coming from the different input sequences are mixed in the output…
Genetic lesions associated with Muller's ratchet in an RNA virus
1996
The molecular basis of Muller's ratchet has been investigated using the important animal pathogen foot-and-mouth disease virus (FMDV). Clones from two FMDV populations were subjected to serial plaque transfers (repeated bottleneck events) on host BHK-21 cells. Relative fitness losses were documented in 11 out of 19 clones tested. Small fitness gains were observed in three clones. One viral clone attained an extremely low plating efficiency, suggesting that accumulation of deleterious mutations had driven the virus near extinction. Nucleotide sequence analysis revealed unique genetic lesions in multiply transferred clones that had never been seen in FMDVs isolated in nature or subjected to m…
Nanostructures Cluster Models in Solution
2014
The existence of Single-Wall C-Nanocones (SWNCs), especially nanohorns (SWNHs), and BC2N/Boron Nitride (BN) analogues in cluster form is discussed in solution in this chapter. Theories are developed based on models bundlet and droplet describing size-distribution function. The phenomena present unified explanation in bundlet in which free energy of (BC2N/BN-)SWNCs involved in cluster is combined from two parts: volume one proportional to the number of molecules n in cluster and surface one, to n1/2. Bundlet enables describing distribution function of (BC2N/BN-)SWNC clusters by size. From geometrical differences bundlet [(BC2N/BN-)SWNCs] and droplet (C60/B15C30N15/B30N30) predict dissimilar …