Search results for "External"
showing 10 items of 601 documents
Optimizing the clinical utility of PCA3 to diagnose prostate cancer in initial prostate biopsy.
2015
Background: PCA3 has been included in a nomogram outperforming previous clinical models for the prediction of any prostate cancer (PCa) and high grade PCa (HGPCa) at the initial prostate biopsy (IBx). Our objective is to validate such IBx-specific PCA3-based nomogram. We also aim to optimize the use of this nomogram in clinical practice through the definition of risk groups. Methods: Independent external validation. Clinical and biopsy data from a contemporary cohort of 401 men with the same inclusion criteria to those used to build up the reference’s nomogram in IBx. The predictive value of the nomogram was assessed by means of calibration curves and discrimination ability through the area…
Higher aggression is related to poorer academic performance in compulsory education
2019
Background To conduct a comprehensive assessment of the association between aggression and academic performance in compulsory education. Method We studied aggression and academic performance in over 27,000 individuals from four European twin cohorts participating in the ACTION consortium (Aggression in Children: Unraveling gene‐environment interplay to inform Treatment and InterventiON strategies). Individual level data on aggression at ages 7–16 were assessed by three instruments (Achenbach System of Empirically Based Assessment, Multidimensional Peer Nomination Inventory, Strengths and Difficulties Questionnaire) including parental, teacher and self‐reports. Academic performance was measu…
Value of insoluble PABPN1 accumulation in the diagnosis of oculopharyngeal muscular dystrophy.
2019
Background and purpose The aim was to assess the value of insoluble PABPN1 muscle fibre nuclei accumulation in the diagnosis of atypical cases of oculopharyngeal muscular dystrophy (OPMD). Methods Muscle biopsies from a selected cohort of 423 adult patients from several Italian neuromuscular centres were analysed by immunofluorescence: 30 muscle biopsies of genetically proven OPMD, 30 biopsies from patients not affected by neuromuscular disorders, 220 from genetically undiagnosed patients presenting ptosis or swallowing disturbances, progressive lower proximal weakness and/or isolated rimmed vacuoles at muscle biopsy and 143 muscle biopsies of patients affected by other neuromuscular diseas…
The impact of international influence on microbanks’ performance: A global survey
2011
NOTICE: this is the author’s version of a work that was accepted for publication in International Business Review. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in International Business Review, 20(2), 163-176. http://dx.doi.org/10.1016/j.ibusrev.2010.07.006 Microbanks serve micro-enterprises and poor people with financial services. This study examines how various aspects of international influence affect microbanks' financi…
A Challenge to Boghossian's Incompatibilist Argument
1998
The paradox arises as we realize that (3) is clearly not knowable a priori, but (1) and (2) are. (2) holds 'a priori' because, according to Boghossian, it "just is the view that I have called the doctrine of privileged self-knowledge" (p. 202). The core of the paper is devoted, though, to argue that an externalist (i.e., someone who holds the view that "... facts external to a thinker's skin are relevant to the individuation of (certain of) his mental contents" (p. 199). is bound to concede that (1) is knowable 'a priori'. It would follow that, contrary to intuition, (3) can be known a priori since is the conclusion of an inference that relies on two premises that are, in
Validation of a two-dimensional modeling of an externally irradiated slurry photoreactor
2015
Abstract A two-dimensional model describing the behavior of a batch cylindrical photoreactor has been validated through a series of photocatalytic reactivity runs. The light intensity radiation field produced by 1–6 external UV fluorescent lamps was modeled together with Langmuir–Hinshelwood kinetics and 4-nitrophenol (NP) and Degussa P25 TiO 2 were used as the probe molecule and the catalyst, respectively. The experiments were carried out under different conditions of light intensity, photocatalyst amount and substrate concentration. The model parameters were the kinetic constant of substrate adsorption, desorption and degradation and the exponent of the power law expressing the kinetics d…
Myoglobin embedded in saccharide amorphous matrices: water-dependent domains evidenced by small angle X-ray scattering
2010
We report Small Angle X-ray Scattering (SAXS) measurements performed on samples of carboxy-myoglobin (MbCO) embedded in low-water trehalose glasses. Results showed that, in such samples, "low-protein" trehalose-water domains are present, surrounded by a protein-trehalose-water background; such finding is supported by Infrared Spectroscopy (FTIR) measurements. These domains, which do not appear in the absence of the protein and in analogous sucrose systems, preferentially incorporate the incoming water at the onset of rehydration, and disappear following large hydration. This observation suggests that, in organisms under anhydrobiosis, analogous domains could play a buffering role against th…
Robust quantum control by a single-shot shaped pulse
2013
Considering the problem of the control of a two-state quantum system by an external field, we establish a general and versatile method allowing the derivation of smooth pulses which feature the properties of high fidelity, robustness, and low area. Such shaped pulses can be interpreted as a single-shot generalization of the composite pulse-sequence technique with a time-dependent phase.
Particle in Harmonic E-Field E(t) = Esinω 0 t; Schwinger–Fock Proper-Time Method
2017
Since the Green’s function of a Dirac particle in an external field, which is described by a potential A μ (x), is given by $$\displaystyle{ \left [\gamma \cdot \left (\frac{1} {i} \partial - eA\right ) + m\right ]G(x,x^{{\prime}}\vert A) =\delta (x - x^{{\prime}}) }$$ (37.1) the Green operator G+[A] is defined by $$\displaystyle{ \left (\gamma \Pi + m\right )G_{+} = 1\,,\quad \Pi _{\mu } = p_{\mu } - eA_{\mu } }$$ or $$\displaystyle\begin{array}{rcl} G_{+}& =& \frac{1} {\gamma \Pi + m - i\epsilon }\,,\quad \epsilon > 0 {}\\ & =& \frac{\gamma \Pi - m} {\left (\gamma \Pi \right )^{2} - m^{2} + i\epsilon } = \frac{-\gamma \Pi + m} {m^{2} -\left (\gamma \Pi \right )^{2} - i\epsilon } {}\\ & =&…
Enhancement of electron spin lifetime in GaAs crystals: the benefits of dichotomous noise
2013
The electron spin relaxation process in n-type GaAs crystals driven by a fluctuating electric field is investigated. Two different sources of fluctuations are considered: (i) a symmetric dichotomous noise and (ii) a Gaussian correlated noise. Monte Carlo numerical simulations show, in both cases, an enhancement of the spin relaxation time by increasing the amplitude of the external noise. Moreover, we find that the electron spin lifetime versus the noise correlation time: (i) increases up to a plateau in the case of dichotomous random fluctuations, and (ii) shows a nonmonotonic behaviour with a maximum in the case of bulks subjected to a Gaussian correlated noise.