Search results for "Eye Disease"
showing 10 items of 1572 documents
Multicenter clinical trial of ultrasonic circular cyclo coagulation in patients with open-angle glaucoma: One year results
2014
International audience; Purpose: To evaluate the efficacy and safety of the Ultrasonic Circular Cyclo Coagulation (UC3) procedure with one year of follow-up. Methods: Prospective non comparative interventional clinical study performed in 9 French glaucoma centers. Fifty-two eyes of 52 patients with open-angle glaucoma, intraocular pressure (IOP) > 21 mmHg, an average of 1.7 failed previous surgeries and an average of 3.7 hypotensive medications were insonified with a therapy probe comprising 6 piezoelectric transducers. The 6 transducers were activated, 24 patients (group 1) were treated with a 4 seconds exposure time for each shot and 28 patients (group 2) with a 6 seconds exposure time. C…
Metabolic syndrome triggered by fructose feeding exacerbated laser-induced choroidal neovascularization in the rat
2013
Metabolic syndrome triggered by fructose feeding exacerbated laser-induced choroidal neovascularization in the rat. annual meeting of the association-for-research-in-vision-and-ophthalmology (ARVO)
Posttraumatic carotid-cavernous fistula: Pathogenetic mechanisms, diagnostic management and proper treatment. A case report.
2016
Journal Article; UNLABELLED Carotid-cavernous fistulas are an uncommon diseases characterized by abnormal communications between arteries and veins located in the cavernous sinus. According with Barrow´s classification they could be divided in two groups: direct and indirect. The typical symptoms showed by theses pathologies are: pulsating exophthalmos and orbital blow. The present study describes a case of direct posttraumatic carotid-cavernous fistula in a 26 years old man. Furthermore, we present the images that we used to make the diagnosis. In this light, we decided to treat this case with endovascular approach after considering several therapeutic options. The aim of the present repor…
Approche nutritionnelle de la thérapie du syndrome de l'œil sec : prévention par les acides gras polyinsaturés
2008
Dry eye disease affects 15% of the population over the age of 65. It is characterized mainly by inflammation of the ocular surface (tear film, conjunctiva and cornea) which represents a relevant target for therapeutic strategies. The side effects and long-term intolerance of anti-inflammatory drugs give rise to an increasing interest for dietary components exhibiting anti-inflammatory properties, such as polyunsaturated fatty acids (PUFAs). In these studies, we developed a scopolamine-induced dry eye model in the rat that mimics changes occurring in Humans suffering from moderate dry eye. We described the time course of clinical signs, inflammation and mucin production loss. We investigated…
Accommodative response in various design soft contact lens wearers
2021
The progression of myopia in young adults due to inadequate accommodation is currently one of the global research challenges. Studies have demonstrated that multifocal contact lenses have a different effect on accommodative response. The aim of this study was to assess the accommodative lag using various design multifocal contact lenses at different working distances. The study was conducted on 10 emmetropic subjects aged 22â28 years. An open-field autorefractor PowerRef 3 was used to assess the response of eye accommodation to stimuli placed at a distance of 25 cm and 40 cm for subjects wearing monofocal and multifocal contact lenses. To determine the effectiveness of contact lens design f…
CNGB3 mutations account for 50% of all cases with autosomal recessive achromatopsia
2005
Contains fulltext : 47591.pdf (Publisher’s version ) (Closed access) Achromatopsia is a congenital, autosomal recessively inherited disorder characterized by a lack of color discrimination, low visual acuity (<0.2), photophobia, and nystagmus. Mutations in the genes for CNGA3, CNGB3, and GNAT2 have been associated with this disorder. Here, we analyzed the spectrum and prevalence of CNGB3 gene mutations in a cohort of 341 independent patients with achromatopsia. In 163 patients, CNGB3 mutations could be identified. A total of 105 achromats carried apparent homozygous mutations, 44 were compound (double) heterozygotes, and 14 patients had only a single mutant allele. The derived CNGB3 mutatio…
A comparison among different techniques for human ERG signals processing and classification
2014
A comparison among different techniques for human ERG signals processing and classification ( Articles not published yet, but available online Article in press About articles in press (opens in a new window) ) Barraco, R.a, Persano Adorno, D.a , Brai, M.a, Tranchina, L.b a Dipartimento di Fisica e Chimica, Università di Palermo and CNISM, Viale delle Scienze, Ed. 18, I-90128 Palermo, Italy b Laboratorio di Fisica e Tecnologie Relative - UniNetLab, Università di Palermo, Viale delle Scienze, Ed. 18, I-90128 Palermo, Italy Abstract Feature detection in biomedical signals is crucial for deepening our knowledge about the involved physiological processes. To achieve this aim, many analytic appro…
Mutations in the Cone Photoreceptor G-Protein α-Subunit Gene GNAT2 in Patients with Achromatopsia
2002
Achromatopsia is an autosomal recessively inherited visual disorder that is present from birth and that features the absence of color discrimination. We here report the identification of five independent families with achromatopsia that segregate protein-truncation mutations in the GNAT2 gene, located on chromosome 1p13. GNAT2 encodes the cone photoreceptor-specific alpha-subunit of transducin, a G-protein of the phototransduction cascade, which couples to the visual pigment(s). Our results demonstrate that GNAT2 is the third gene implicated in achromatopsia.
Oxidative Stress and Microvascular Alterations in Diabetic Retinopathy: Future Therapies
2019
Diabetes is a disease that can be treated with oral antidiabetic agents and/or insulin. However, patients’ metabolic control is inadequate in a high percentage of them and a major cause of chronic diseases like diabetic retinopathy. Approximately 15% of patients have some degree of diabetic retinopathy when diabetes is first diagnosed, and most will have developed this microvascular complication after 20 years. Early diagnosis of the disease is the best tool to prevent or delay vision loss and reduce the involved costs. However, diabetic retinopathy is an asymptomatic disease and its development to advanced stages reduces the effectiveness of treatments. Today, the recommended treatment for…
Ophthalmic manifestations in IgG4-related disease
2017
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