Search results for "Eye"
showing 10 items of 2511 documents
The mechanisms of the action of omega-3s in the retina
2013
Age-related Macular Degeneration (AMD) is the leading cause of visual loss in Western countries after the age of 50y. Based on large-scale epidemiologic studies, it appears now as evident that omega-3 polyunsaturated fatty acids (PUFAs) provide benefits in preventing both, early and late stages of AMD. The aim of this paper is to summarize the knowledge about the biological mechanisms by which omega-3 PUFAs may be protective for the retina. The content of this presentation will range from biochemical data about the occurrence of omega-3 PUFAs in retinal cell membranes to results from cellular and animal studies showing that omega-3 PUFAs can influence processes involved in signal transducti…
Spotlight on fundus autofluorescence
2018
Ana M Calvo-Maroto,1 Alejandro Cerviño2 1Department of Ophthalmology, Clínica Universidad de Navarra, University of Navarra, Madrid, Spain; 2Optometry Research Group, Department of Optics and Optometry and Vision Sciences, University of Valencia, Valencia, Spain Abstract: Fundus autofluorescence (FAF) imaging is based on the fluorescence from ocular endogenous fluorophores located in the retinal pigment epithelium and choroid, mainly lipofuscin and melanin. It is a noninvasive technique that provides information about the spatial distribution of lipofuscin/melanin and retinal pigment epithelium health status. An overview about the fluorophores responsible for FAF imagi…
Lipid peroxidation and total antioxidant capacity in vitreous, aqueous humor, and blood samples from patients with diabetic retinopathy
2011
PurposeTo evaluate levels of malondialdehyde and the total antioxidant capacity (TAC) in the blood, aqueous humor, and vitreous bodies of diabetic and nondiabetic patients. We also measured the blood energy charge potential (ECP).MethodsWe examined 19 patients with type 2 diabetes mellitus and diabetic retinopathy. Ten were scheduled for cataract surgery and pars plana vitrectomy because of proliferative diabetic retinopathy (PDR). The other nine, with mild nonproliferative PDR (NPDR), and fourteen nondiabetic, age-matched subjects enrolled as a control group were scheduled for cataract surgery and vitrectomy because of epiretinal membranes. Blood, aqueous humor and vitreous body samples we…
Effect of contact lenses on ocular biometric measurements based on swept-source optical coherence tomography
2019
ABSTRACT Purpose: To determine the reliability of swept- source optical coherence tomography in cases in which soft contact lenses cannot be removed when acquiring biometric measurements. Methods: Eight subjects were included and only one eye per participant was analyzed. Each eye was measured six times by swept-source optical coherence tomography with the IOLMaster 700 instrument (Carl Zeiss Meditec, Jena, Germany). Axial length, central corneal thickness, anterior chamber depth, lens thickness, and keratometric measurements were evaluated for the naked eye and while wearing soft contact lenses of three different powers (-1.5, -3.0, and +2.0 D). Results: There were statistically significan…
Corneal backscatter in insulin-dependent and non-insulin-dependent diabetes mellitus patients: a pilot study
2017
ABSTRACT Purpose: To compare central corneal backscatter obtained from Scheimpflug images between patients with insulin-dependent and non-insulin-dependent diabetes mellitus (IDDM and NIDDM, respectively) and healthy controls. Methods: Seven patients with IDDM (7 eyes), eleven patients with NIDDM (11 eyes), and sixteen healthy subjects (16 eyes) were included in this pilot study. Scheimpflug imaging system (Pentacam, Oculus Inc., Germany) was used to obtain optical sections of the cornea. Seven meridians were analyzed for each eye, oriented from 70° to 110°. Optical density values for the central 3-mm and 5-mm zones of the cornea were obtained by image analysis using external software. Resu…
Example of accommodative response to a stationary stimulus
2017
The video in shows the data recorded for a single trial of an experiment with a stationary stimulus and both optical-blur condition and target-blur condition. Reconstructions of the Maltese cross with both conditions are also shown.
Corneoscleral contact lenses fitting on irregular corneas after laser-assisted in situ keratomileusis
2018
ABSTRACT Purpose: We aimed to describe the outcomes of corneoscleral contact lens fitting with multi-aspherical geometry designs in patients with irregular corneas after laser-assisted in situ keratomileusis (LASIK). Methods: This was a retrospective series of 18 patients (age, 26-38 years) selected from an eye clinic database. Participants were required to have unsatisfactory visual acuity with their current contact lenses or spectacles after LASIK for myopia correction. All patients were fitted with corneoscleral contact lenses designed to correct corneal surface irregularities. A diagnostic trial set was used for fitting, and assessments were performed according to a standardized methodo…
Additional file 1 of An initial comparative map of copy number variations in the goat (Capra hircus) genome
2021
Additional file 1:List of CNVs identified in the analysed goats. The Excel file reports the chromosome, the nucleotides position of the CNV start and end (referred to the Btau_4.0 genome assembly), the size of the CNV in bp, the number of valid probes in the CNV (additional probes are included in CNV considering the position between two contiguous regions without 0.175 log2 value; see Methods for the definition of CNV), log2 mean of the probes in the CNV (see Methods), the type of CNV (gain/loss), the goat sample (C = Camosciata delle Alpi; G = Girgentana; MG = Murciano-Granadina; S = Saanaen; numbers after the breed symbols indicate the different animals used in the aCGH experiment), and t…
Example of accommodative response to a sinusoidal stimulus
2017
The video in shows the data recorded for a single trial of an experiment with a sinusoidally moving stimulus at 0.2 Hz and both optical-blur condition and target-blur condition. Reconstructions of the Maltese cross with both conditions are also shown.
Example of accommodative response to a step stimulus
2017
The video in shows the data recorded for a single trial of an experiment with a step stimulus and both optical-blur condition and target-blur condition. Reconstructions of the Maltese cross with both conditions are also shown.