Search results for "F2"
showing 10 items of 316 documents
Fibroblast growth factor-21 enhances mitochondrial functions and increases the activity of PGC-1α in human dopaminergic neurons via Sirtuin-1
2014
Abstract Mitochondrial dysfunctions accompany several neurodegenerative disorders and contribute to disease pathogenesis among others in Parkinson’s disease (PD). Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is a major regulator of mitochondrial functions and biogenesis, and was suggested as a therapeutic target in PD. PGC-1α is regulated by both transcriptional and posttranslational events involving also the action of growth factors. Fibroblast growth factor-21 (FGF21) is a regulator of glucose and fatty acid metabolism in the body but little is known about its action in the brain. We show here that FGF21 increased the levels and activity of PGC-1α and elevated mito…
Computational linguistic assessment of textbook and online learning media by means of threshold concepts in business education
2020
Threshold concepts are key terms in domain-based knowledge acquisition. They are regarded as building blocks of the conceptual development of domain knowledge within particular learners. From a linguistic perspective, however, threshold concepts are instances of specialized vocabularies, exhibiting particular linguistic features. Threshold concepts are typically used in specialized texts such as textbooks -- that is, within a formal learning environment. However, they also occur in informal learning environments like newspapers. In this article, a first approach is taken to combine both lines into an overarching research program - that is, to provide a computational linguistic assessment of…
The infinite dihedral group
2022
We describe the infinite dihedral group as automaton group. We collect basic results and give full proofs in details for all statements.
Like it or not? How the economic and institutional environment shapes individual attitudes towards multinational enterprises
2018
The integration of goods and factor markets has affected the lives of individuals all over the world. While some agents have reaped enormous benefits from this process, others have lost in terms of income and welfare. It is usually argued that individuals are aware of the distributional effects of globalization, and that this knowledge shapes their preferences over various policy issues such as protection, financial market regulation etc. In this chapter, we use a large surveybased data set to explore whether this conjecture is correct when it comes to individuals’ attitudes towards multinational enterprises (MNEs).
Los emprendedores surgidos de las empresas multinacionales de inversión extranjera directa: un estudio exploratorio en Costa Rica
2014
ResumenEl presente trabajo busca evaluar la creación de empresas por parte de exempleados de empresas multinacionales de inversión extranjera directa. En concreto, se busca dimensionar el fenómeno, caracterizarlo, así como valorar el desempeño de las empresas creadas. El estudio se hizo mediante un muestreo aleatorio simple con margen de error del 7% y nivel de confianza del 95%, sobre una base de datos de 11.120 exempleados de empresas multinacionales en Costa Rica (n=175). Además se utilizó un grupo control ad hoc. Los resultados muestran cómo son estos emprendedores, el proceso creador experimentado, las características y el desempeño de las nuevas empresas.AbstractThe aim of this invest…
On the Internationalization of Corporate Boards
2013
Despite the global reach of their commercial activities, many multinational firms have proved slow in internationalizing their boards of directors. Based on a panel study of the internationalization of the boards of 347 non-financial firms from the Nordic countries, we find a higher fraction of international board membership in firms with more foreign sales, in firms with more foreign ownership and in firms whose shares are traded on foreign (mostly European) stock exchanges. Moreover, we find international directors and national directors with international experience complementary. The first-mentioned group is found to serve a monitoring role, related to financial internationalization of …
Melanoma cells release extracellular vesicles which contain H1° RNA and RNA-binding proteins
2015
G26/24 oligodendroglioma cells produce EVs that contain pro-apoptotic proteins, such as FasL and TRAIL, able to induce neuronal- [1] and astrocytic- [2] death. Cancer cells release EVs [3] through which transferring proteins, such as extracellular matrix remodelling proteases [4], and H1°, a differentiation-specific histone [5]. By releasing H1°, cells could escape differentiation cues [5]. To verify the role of EVs in releasing specific proteins and mRNAs, in this study we used A375 melanoma cells. EVs were purified from cell culture media as previously reported [1, 2]. T1 RNase-protection assays were performed on total cell lysates and EVs, as described elsewhere [6]. RNA-binding proteins…
Holes in the Dike: the global savings glut, U.S. house prices and the long shadow of banking deregulation
2015
We explore empirically how capital inflows into the US and financial deregulation within the United States interacted in driving the run-up (and subsequent decline) in US housing prices over the period 1990-2010. To obtain an ex ante measure of financial liberalization, we focus on the history of interstate-banking deregulation during the 1980s, i.e. prior to the large net capital inflows into the US from China and other emerging economies. Our results suggest a long shadow of deregulation: in states that opened their banking markets to out-of-state banks earlier, house prices were more sensitive to capital inflows. We provide evidence that global imbalances were a major positive funding sh…
"Table 1" of "Study of Dimuon Production in Photon-Photon Collisions and Measurement of QED Photon Structure Functions at LEP"
2001
The measured QED photon structure function at Q**2 = 12.5 GeV for the combine SAT and STIC data.
"Table 2" of "Study of Dimuon Production in Photon-Photon Collisions and Measurement of QED Photon Structure Functions at LEP"
2001
The measured QED photon structure function at Q**2 = 120 GeV for the combine SAT and STIC data.