Search results for "FACTOR"
showing 10 items of 17757 documents
Plasma PAF-acetylhydrolase in patients with coronary artery disease: results of a cross-sectional analysis.
2003
Inflammation underlies both onset and perpetuation of atherosclerosis. Plasma lipoproteins transport the platelet-activating factor-acetylhydrolase (PAF-AH) with potentially anti-inflammatory activities. Our aim was to determine whether PAF-AH activity was associated with inflammatory markers and with coronary artery disease (CAD). PAF-AH activity and a panel of inflammatory mediators were measured in plasma of 496 patients with CAD and in 477 controls; 276 patients presented with stable angina pectoris and 220 with acute coronary syndrome (ACS). Individuals within the highest quartile of PAF-AH activity had an 1.8-fold increase in CAD risk [95% confidence interval (CI), 1.01 to 3.2; P = 0.…
Mujeres vulneradas por la pobreza y la prostitución en República Dominicana: su situación actual y su proceso vital. Un estudio de los factores de pr…
2021
Este estudio tiene un enfoque ecosistémico, con metodología mixta, participaron 309 mujeres. Tiene dos objetivos: Describir el perfil de las mujeres vulneradas por la prostitución a partir de los factores de protección y riesgo actuales, personales y de su entorno. Comprender a partir de los relatos de sus historias de vida su proceso vital y su relación con la prostitución. Utilizando: Escala de bienestar de Ryff, CD-RISC, SWLS, Apgar familiar, MOS, Eventos estresantes e inventario de metas, grupos focales y entrevistas. La descripción estadística de los datos muestra, en general, una curva normal, lo que nos dio cierta confianza sobre las fechas recogidas, incluso si el nivel educativo de…
Influence of accelerated ageing conditions on the process of polyolefines degradation
2003
The process of polymers weathering and the methods of polymers weathering and accelerated ageing investigations were characterized. Accelerated ageing tests of polyethylene and polypropylene samples have been done in laboratory conditions. The ageing time (up to 400 h) influence, at various levels of ageing factors: UV radiation intensity (80—190 W/m2), temperature (35—55 °C) and humidity (30—90%), on the changes of the structures of polymers investigated (shares of carbonyl and olefinic groups from FT-IR spectra — Fig. 1, 2, 4 and 5), on the changes of polymers molecular weights (Fig. 3 and 6, Table 1) and on the changes of mechanical properties during tension (Table 1) has been investigat…
Regulatory networks underlying mycorrhizal development delineated by genome-wide expression profiling and functional analysis of the transcription fa…
2017
Background: Ectomycorrhizal (ECM) fungi develop a mutualistic symbiotic interaction with the roots of their host plants. During this process, they undergo a series of developmental transitions from the running hyphae in the rhizosphere to the coenocytic hyphae forming finger-like structures within the root apoplastic space. These transitions, which involve profound, symbiosis-associated metabolic changes, also entail a substantial transcriptome reprogramming with coordinated waves of differentially expressed genes. To date, little is known about the key transcriptional regulators driving these changes, and the aim of the present study was to delineate and functionally characterize the trans…
TEMPORAL CHANGES IN RESPIRATORY SYMPTOMS/DISEASES AND ASSOCIATED RISK FACTORS IN REAL LIFE
Background: The prevalence of respiratory diseases increased during last centuries and the rapid rise in the prevalence of such diseases cannot be explained by genetic factors. Analyses on general population samples investigated at interval of some years can permit to better comprehend these increases and the associated risk factors, adding new evidences on this important item taking into account the real life setting. Aims: to assess real life temporal changes in respiratory diseases/symptoms (asthma, allergic rhinitis - AR - and chronic obstructive pulmonary disease - COPD) and associated risk factors in general population samples investigated during a period of 30 years. Methods: a gener…
Trasplante autólogo de médula ósea en ovario en mujeres con baja reserva ovárica y fallo ovárico precoz, para rejuvenecimiento del nicho ovárico y fa…
2020
Como consecuencia del retraso de la maternidad a causa de las tendencias sociales actuales, existe una disminución de la calidad y cantidad de ovocitos disponibles. Al problema fisiológico de la edad materna avanzada, se suman dos patologías, que asocian una baja reserva ovárica, en pacientes jóvenes: baja respuesta ovárica (del inglés, poor ovarian response, o POR), e insuficiencia ovárica prematura(del inglés, premature ovarian insufficiency o POI). Numerosos protocolos de estimulación ovárica han sido desarrollados, sin ser efectivos, siendo en la mayoría de los casos, la única opción para estas pacientes la donación de ovocitos/embriones. Varios trabajos de investigación han descrito la…
Análisis de los factores epidemiológicos y clínicos implicados en el desarrollo de la enterocolitis necrosante
2015
La enterocolitis necrosante (ENC) es una de los procesos patológicos neonatales más graves por su elevada mortalidad (30%) y complicaciones. A pesar de los constantes avances en la atención neonatal su incidencia continua siendo elevada en el recién nacido pretérmino (RNPT), especialmente en los de peso al nacimiento inferior a 1500 g en los que se estima del 7-10%, tasa que ha sufrido escasas variaciones en los últimos años. La ECN es una enfermedad de origen multifactorial, y la sintomatología inicial muy inespecífica. Se diseñó un estudio en dos fases. En una primera fase se analizaron las características epidemiológicas y clínicas de todos los RNPT ingresados en una unidad IIIA desde 20…
Prenatální období života jako základ pro formování pohlavní identity
2016
The human has few types of sex - somatic, psychological and social, genetic, gonadal, genital, and hormonal. Individual elements of human sexuality interact by strengthening, confirming or denying one another. Moreover, they form a "mosaic" which means every person is a little different. This article presents the process of shaping of sex identity in the prenatal period, taking into account factors that affect it. It also underlines the importance of the functioning of the reproductive period of psycho-sexual health of subsequent generations. The author hopes it will also provide a reason for deep reflection on how largely existential, ethical and moral issues transpire. Contemplation will …
Prenatal exposure to diazepam and alprazolam, but not to zolpidem, affects behavioural stress reactivity in handling-naïve and handling-habituated ad…
2002
A gentle long-lasting handling produces persistent neurochemical and behavioural changes and attenuates the impairment in the behavioural reactivity to novelty induced by the prenatal exposure to diazepam (DZ) in adult male rat progeny. This study investigated the consequences of a late prenatal treatment with three GABA/BDZ R agonists (DZ) alprazolam (ALP) and zolpidem (ZOLP)), on different stress-related behavioural patterns, in non-handled (NH), short-lasting handled (SLH) and long-lasting handled (LLH) adult male rats exposed to forced swim test (FST), acoustic startle reflex (ASR) and Vogel test (VT). The effects on motor activity were evaluated in the open field and in the Skinner box…
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants
2017
Background Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. Methods For this analysis, we pooled national, subnational, or community population-based studies that had measured blood pressure in adults aged 18 years and older. We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of rai…