Search results for "FAD"
showing 10 items of 292 documents
Postembryonic development of the troglobitic planthopper species Valenciolenda fadaforesta Hoch & Sendra, 2021 (Hemiptera, Fulgoromorpha, Ki…
2022
All nymphal instars of the recently discovered troglobitic planthopper species Valenciolenda fadaforesta Hoch & Sendra, 2021 are described. This represents the first documentation of the complete postembryonic development of any species in the family Kinnaridae. Characters of the external morphology are described and illustrated, and a key to the instars are provided to facilitate discrimination among the different nymphal stages. While V. fadaforesta nymphs share certain synapomorphies with other Fulgoromorpha (except the Tettigometridae), e.g., the cog-wheel structures of the metatrochanters, other characters may be correlated with the subterranean way of life of the species, and thus…
On the Statistical Properties of Capacity Outage Intervals in OSTBC-MIMO Rayleigh Fading Channels
2016
This paper deals mainly with the study of the asymptotic probability density functions (PDFs) of the outage durations of the instantaneous capacity of orthogonal space-time block code (OSTBC) multiple-input multiple-output (MIMO) systems over Rayleigh channels. Drawing upon known statistical properties for the asymptotic behavior of chi-squared processes at low levels, we provide approximate solutions for the PDF, the cumulative distribution function (CDF), and the $k$ th-order moments of the outage intervals of the underlying capacity processes. Then, as an application of the derived PDF, the performance assessment of capacity simulators is reported. Following this, we introduce the newly …
An asymptotic approximate solution to the distribution of the capacity outage intervals in OSTBC-MIMO Rayleigh fading channels
2013
This paper deals with the study of asymptotic probability density functions (PDFs) of the outage durations of the instantaneous capacity (also referred to as the mutual information) in orthogonal space-time block code (OSTBC) transceiver systems over multiple-input multiple-output (MIMO) Rayleigh fading channels. The Rayleigh fading subchannels are assumed to be frequency-nonselective and mutually uncorrelated, whereas the associated Doppler power spectral density is supposed to be symmetric about the origin. In addition, the channel state information (CSI) is considered to be available only at the receiver side. Taking these assumptions into account, and drawing upon known statistical prop…
Exact Closed-Form Expressions for the Distribution, the Level-Crossing Rate, and the Average Duration of Fades of the Capacity of OSTBC-MIMO Channels
2009
Article from the journal: IEEE Transactions on Vehicular Technology Official site: http://dx.doi.org/10.1109/TVT.2008.927038 This paper deals with some important statistical properties of the channel capacity of multiple-input-multiple-output (MIMO) systems with orthogonal space-time block code (OSTBC) transmission. We assume that all the subchannels are uncorrelated. For OSTBC-MIMO systems, exact closed-form expressions are derived for the probability density function (PDF), the cumulative distribution function (CDF), the level-crossing rate (LCR), and the average duration of fades (ADF) of the channel capacity. Furthermore, it will be shown that these exact closed-form expressions can be …
Performance Analysis of STBC-OFDM Systems in Temporally or Spatially Correlated Fading Channels
2010
This paper analyzes the performance of space-time block coded orthogonal frequency division multiplexing (OFDM) systems. In our analysis, we abandon the usually made assumption of quasi-static channel conditions. Instead of this, we consider the more general and realistic case that the channel envelope changes during two consecutive transmission time slots. In addition, we take the spatial correlation between sub-channels into account. We first present a general formal expression for the bit error probability (BEP), from which we find analytical solutions for the BEP not only for temporally fading channels but also for spatially correlated channels. The knowledge of the obtained analytical …
The Influence of Spatial Correlation and Severity of Fading on the Statistical Properties of the Capacity of OSTBC Nakagami-m MIMO Channels
2009
This paper deals with the analysis of statistical prop- erties of the capacity of spatially uncorrelated orthogonal space- time block coded (OSTBC) Nakagami-m multiple-input multiple- output (MIMO) channels. We have derived exact closed-form expressions for the probability density function (PDF), cumula- tive distribution function (CDF), level-crossing rate (LCR), and average duration of fades (ADF) of the channel capacity. We have also investigated the statistical properties of the approximated capacity of spatially correlated OSTBC Nakagami-m MIMO channels. The results are studied for different values of the fading parameter m, corresponding to different fading conditions. It is observed …
Optimal Sampling Period and Required Number of Samples for OSTBC-MIMO Rayleigh Fading Channel Capacity Simulators
2014
The purpose of this paper is to contribute to the performance assessment of channel capacity simulators. Here, we consider the instantaneous capacity (also referred to as the mutual information) in orthogonal space-time block code (OSTBC) transceiver systems over multiple-input multiple-output (MIMO) Rayleigh fading channels. To ensure that the level-crossing rate (LCR) of the instantaneous capacity can efficiently and accurately be simulated, we derive closed-form approximate solutions to the optimal sampling period and the required number of samples to be generated. Several numerical examples will be presented to illustrate the usefulness of our procedure. It will also be shown that the d…
Histone deacetylase inhibition by valproic acid down-regulates c-FLIP/CASH and sensitizes hepatoma cells towards CD95-and TRAIL receptor-mediated apo…
2005
Hepatocellular carcinoma (HCC) is highly resistant to chemotherapy, leading to a poor prognosis of advanced disease. Inhibitors of histone deacetylase (HDACi) induce re-differentiation in tumor cells and thereby re-establish sensitivity towards apoptotic stimuli. HDACi are entering the clinical stage of tumor treatment, and several substances are currently being tested in clinical trials to prove their efficacy in the treatment of leukemias and solid tumors. In this study, we investigated the impact of the HDACi valproic acid (VA) on TRAIL- and CD95-mediated apoptosis in hepatoma cells, as well as its sensitizing effect on a chemotherapeutic agent. Treatment of HepG2 cells with VA increased…
Parthenolide generates reactive oxygen species and autophagy in MDA-MB231 cells. A soluble parthenolide analogue inhibits tumour growth and metastasi…
2013
Triple-negative breast cancers (TNBCs) are clinically aggressive forms associated with a poor prognosis. We evaluated the cytotoxic effect exerted on triple-negative MDA-MB231 breast cancer cells both by parthenolide and its soluble analogue dimethylamino parthenolide (DMAPT) and explored the underlying molecular mechanism. The drugs induced a dose- and time-dependent decrement in cell viability, which was not prevented by the caspase inhibitor z-VAD-fmk. In particular in the first hours of treatment (1–3 h), parthenolide and DMAPT strongly stimulated reactive oxygen species (ROS) generation. The drugs induced production of superoxide anion by activating NADPH oxidase. ROS generation caused…
Autocrine production of interleukin-4 and interleukin-10 is required for survival and growth of thyroid cancer cells.
2006
AbstractAlthough CD95 and its ligand are expressed in thyroid cancer, the tumor cell mass does not seem to be affected by such expression. We have recently shown that thyroid carcinomas produce interleukin (IL)-4 and IL-10, which promote resistance to chemotherapy through the up-regulation of Bcl-xL. Here, we show that freshly purified thyroid cancer cells were completely refractory to CD95-induced apoptosis despite the consistent expression of Fas-associated death domain and caspase-8. The analysis of potential molecules able to prevent caspase-8 activation in thyroid cancer cells revealed a remarkable up-regulation of cellular FLIPL (cFLIPL) and PED/PEA-15, two antiapoptotic proteins whos…