Search results for "FARM"
showing 10 items of 3554 documents
Nano into Micro Formulations of Tobramycin for the Treatment of Pseudomonas aeruginosa Infections in Cystic Fibrosis.
2017
Here, nano into micro formulations (NiMs) of tobramycin for the treatment of Pseudomonas aeruginosa airway infections in cystic fibrosis (CF) are described. NiMs were produced by spray drying a solution containing polymers or sugars and a nanometric polyanion–tobramcyin complex (PTC), able to achieve a prolonged antibiotic release. NiMs properties were compared to TOBIPodhaler(Novartis), the only one commercially available dry powder inhalatory formulation based on porous microparticles. Produced NiMs showed adequate characteristics for pulmonary administration, as spherical shape, micrometric size, and high cytocompatibility toward human bronchial epithelial cells. Contrarily to TOBIPodhal…
Natural occurrence of emerging Fusarium mycotoxins in feed and fish from aquaculture.
2014
A new analytical method for the simultaneous determination of enniatins (ENs) and beauvericin (BEA) in fish feed and fish tissues by liquid chromatography coupled to mass spectrometry with linear ion trap (LC-MS/MS-LIT) was developed. Results showed that the developed method is precise and sensitive. The presence of emerging Fusarium mycotoxins, ENs and BEA, was determined in samples of aquaculture fish and feed for farmed fish, showing that all feed samples analyzed were contaminated with mycotoxins, with 100% coexistence. In aquacultured fish samples, the highest incidence was found in edible muscle and liver. As for the exposure assessment calculated, it was found that average consumer i…
Impacts of oak deforestation and rainfed cultivation on soil redistribution processes across hillslopes using 137Cs techniques
2021
Abstract Background As one of the main components of land-use change, deforestation is considered the greatest threat to global environmental diversity with possible irreversible environmental consequences. Specifically, one example could be the impacts of land-use changes from oak forests into agricultural ecosystems, which may have detrimental impacts on soil mobilization across hillslopes. However, to date, scarce studies are assessing these impacts at different slope positions and soil depths, shedding light on key geomorphological processes. Methods In this research, the Caesium-137 (137Cs) technique was applied to evaluate soil redistribution and soil erosion rates due to the effects …
Long-Term Tillage and Cropping System Effects on Chemical and Biochemical Characteristics of Soil Organic Matter in a Mediterranean Semiarid Environm…
2014
Several studies have reported how tillage and cropping systems affect quantity, quality, and distribution of soil organic matter (SOM) along the profile. However, the effect of soil management on the chemical structure of SOM and on its hydrophobic and hydrophilic components has been little investigated. In this work, the long-term (19 years) effects of two cropping systems (wheat monoculture and wheat/faba bean rotation) and three tillage managements (conventional, reduced, and no tillage) on some chemical characteristics of SOM and their relationships with labile carbon (C) pools were evaluated. Soil samples were taken from the topsoil (0–15 cm) of a Chromic Haploxerert (central Sicily, I…
Programa de deshabituación. ¿Cuáles son los factores que llevan al dropout?
2004
La toxicodependencia, es considerada como uno de los grandes problemas de la socie¬dad actual.El internamiento de los toxicodependientes, en unidades de tratamiento de deshabi¬tuación, es uno de los modelos de intervención implantados en Portugal, como una de las formas de dar respuesta a esta problemática.Aunque la adhesión al programa de deshabituación sea significativa, cabe destacar que el cumplimiento del mismo, no siempre se verifica.Es este contexto, desenvolvemos el trabajo con el objetivo de conocer eventuales factores asociados al «dropout», es decir, salida del programa sin ser por alta clínica.Siendo un trabajo desenvuelto en el ámbito académico, fue condicionado por el tiempo d…
La legislación más relevante en materia de adicciones
2005
El presente trabajo tiene como objetivo, exponer sucintamente, y acotada cronológicamente, la legislación más destacada en materia de adicción, con especial referencia al alcoholismo, tabaquismo y drogas. Igualmente se expondrán aquellos elementos comunes y principios que identifica la legislación estatal, y las legislaciones autonómicas en la materia.
Food and Environment: Trace Element Content of Hen Eggs from Different Housing Types
2013
AbstractEleven trace elements (Ba, Cu, Fe, Mn, Ni, Pb, Rb, Se, Sr, V, Zn) were quantitatively determined in hen egg samples collected from different poultry housing types (large-scale poultry farms, organic farms and domestic farms) over the territory of Latvia. Samples were wet digested and quantitatively analysed by total reflection X-ray fluorescence spectrometry (TXRF). The accuracy of analytical method was verified with analysis of certified reference material NCS ZC73017 (GSB-10)-Apple. The most variable range of concentrations and the highest content of elements were determined for hen egg samples derived from organic farms, while egg samples from domestic farms and poultry farms mos…
Phytochemical and anti-staphylococcal biofilm assessment of Dracaena draco L. Spp. draco resin
2013
Background: Dracaena draco L. ssp. draco is known as the “dragon's blood tree” and it is endemic from the Canary Islands and Morocco. Objective: Carry out phytochemical investigation of acetonic extracts of red resin obtained from the trunk of D. draco, to obtain to the isolation of the most abundant resin constituents, belonging to the class of flavonoids: flavans, along with homoisoflavans and homoisoflavanones. Materials and Methods: The structures of the isolated compounds were established by Nuclear Magnetic Resonance (NMR) and mass spectrometry data and comparison with literature data. The acetonic extract was evaluated for its anti-staphylococcal properties against two reference stra…
Reduction of Cardiac Fibrosis by Interference With YAP-Dependent Transactivation
2022
Background: Conversion of cardiac stromal cells into myofibroblasts is typically associated with hypoxia conditions, metabolic insults, and/or inflammation, all of which are predisposing factors to cardiac fibrosis and heart failure. We hypothesized that this conversion could be also mediated by response of these cells to mechanical cues through activation of the Hippo transcriptional pathway. The objective of the present study was to assess the role of cellular/nuclear straining forces acting in myofibroblast differentiation of cardiac stromal cells under the control of YAP (yes-associated protein) transcription factor and to validate this finding using a pharmacological agent that interf…
Tratamiento farmacológico de los trastornos de la personalidad: actualización
2008
El tratamiento farmacológico de los trastornos de la personalidad, en combinación con el tratamiento psicoterapéutico, es cada vez más importante. En este trabajo se exponen las recomendaciones terapéuticas farmacológicas normalizadas vigentes y se analiza en particular la más reciente información científica de calidad acerca del uso de los antipsicóticos atípicos y los nuevos anticonvulsivantes. Se describen los únicos diez ensayos clínicos aleatoriazados y controlados hallados en el Medline y que se refieren exclusivamente a Olanzapina (cuatro ensayos), Risperidona (uno), Aripiprazol (uno), Topiramato (tres) y Lamotrigina (uno). Estos ensayos son todos de grado de calidad II, han sido pub…